P.121 Ruptured intracranial infectious aneurysms: single Canadian center experience

Abstract

Background: Ruptured Intracranial Infected Aneurysms (IIAs) are relatively rare, but they portend high mortality. To our knowledge, there are no Canadian case-series on IIA, as well there is a relative paucity of international published experiences. Our purpose is to share the experience of a single Canadian tertiary centre in managing ruptured IIA and to conduct a systematic review. Methods: We did a retrospective case review series of adult patients with ruptured IIA treated at our institution. Secondly, we conducted a systematic review of literature on ruptured IIA between 2011-2021 inclusive. Results: At our institution, of a total 8 cases with ruptured IIA, 4 were treated endovascularly and 2 by surgical bypass. For the systematic review, we included 9 non-comparative studies with a total of 509 patients (318 males) and at least 437 ruptured IIA aneurysms. Favourable outcome was specified for 63.3% of patients (n=57). Regarding ruptured IIA, favourable clinical outcome was described in 59.3% (n=16). Conclusions: This study highlights a single Canadian tertiary centre experience in the management of IIA and compares it to the global trends of the last 10 years in a systematic review.