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Noradrenergic Function and Depression, Too Much or Too Little?

Published online by Cambridge University Press:  18 September 2015

J.W. Maas  and
Y. Huang
J.W. Maas*
Affiliation:
Department of Psychiatry, School of Medicine, Yale University, New Haven, Connecticut
Y. Huang
Affiliation:
Department of Psychiatry, School of Medicine, Yale University, New Haven, Connecticut
*
Dept. of Psychiatry, School of Medicine, Yale University, New Haven, Connecticut, U.S.A. 06516
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Summary:

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Antithetical hypotheses as to CNS noradrenergic function in depressed patients can be constructed from results of pharmacological studies of the effects of antidepressant drugs. The experimental data supporting each of these opposing propositions is briefly reviewed in this paper. Finally, the results of clinical studies of noradrenergic function in depressed patients are noted and discussed in terms ofthese disparate hypotheses.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 7 , Issue 3 , August 1980 , pp. 267 - 268
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

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