Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-23T20:57:02.743Z Has data issue: false hasContentIssue false
  • English
  • Français

Mixed Dementia in Clinical Trials of Alzheimer's Disease

Published online by Cambridge University Press:  02 December 2014

Fadi Massoud
Fadi Massoud*
Affiliation:
Department de Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorial
Information
Canadian Journal of Neurological Sciences , Volume 39 , Issue 5 , September 2012 , pp. 566 - 567
Copyright
Copyright © The Canadian Journal of Neurological 2012

References

1.Langa, KM, Foster, NL, Larson, EB.Mixed dementia - emerging concepts and therapeutic implications. JAMA. 2004;292:2901–8.Google Scholar
2.Zekry, D, Hauw, JJ, Gold, G.Mixed dementia: epidemiology, diagnosis, and treatment. J Am Geriatr Soc. 2002;50:1431–8.CrossRefGoogle ScholarPubMed
3.Korczyn, A.Mixed dementia - the most common cause of dementia. Ann NY Acad Sci. 2002;977:129–34.CrossRefGoogle ScholarPubMed
4.Roman, GC, Tatemichi, TK, Erkinjuntti, T, et al.Vascular dementia: diagnostic criteria for research studies: report of the NINDSAIREN International Workshop. Neurology. 1993;43:250–60.CrossRefGoogle ScholarPubMed
5.Chui, H, Victoroff, J, Margolin, D, et al.Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer’s Disease Diagnostic and Treatment Centers. Neurology. 1992;42:473–80.Google Scholar
6.Gorelick, PB, Scuteri, A, Black, SE, et al.Vascular contributions to cognitive impairment and dementia - a statement for healthcare professionals from the American Heart Association / American Stroke Association. Stroke. 2011; 42:2672–713.Google Scholar
7.Feldman, H, Levy, AR, Hsiung, G-Y, et al.A Canadian cohort study of cognitive impairment and related dementias (ACCORD): study methods and baseline results. Neuroepidemiology. 2003; 22:265–74.Google Scholar
8.Lopez, OL, Kuller, LH, Becker, JT, et al.Classification of vascular dementia in the Cardiovascular Health Study Cognition Study. Neurology. 2005:64:1539–47.Google Scholar
9.Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Pathological correlates of late-onset dementia in a multicentre, communitybased population in England and Wales. Lancet. 2001:357: 169–75.Google Scholar
10.Schneider, JA, Arvanitakis, Z, Bang, W, Bennet, DA.Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology. 2007;69:2197–204.CrossRefGoogle ScholarPubMed
11.Wang, BW, Lu, E, Mackenzie, IRA, et al.Multiple pathologies are common in Alzheimer patients in clinical trials. Can J Neurol Sci. 2012;39(5):592–9.CrossRefGoogle ScholarPubMed
12.Zekry, D, Duyckaerts, C, Moulias, R, et al.Degenerative and vascular lesions of the brain have synergistic effects in dementia of the elderly. Acta Neuropath. 2002;103:481–7.CrossRefGoogle ScholarPubMed
13.Hampel, H, Wilcock, G, Andrieu, S, et al.Biomarkers for Alzheimer’s disease therapeutic trials. Prog Neurobiol. 2011;95:579–93.CrossRefGoogle ScholarPubMed
14.Moorhouse, P, Rockwood, K.Vascular cognitive impairment: current concepts and clinical developments. Lancet Neurol. 2008;7:246–55.Google Scholar
15.Deschaintre, Y, Richard, F, Leys, D, Pasquier, F.Treatment of vascular risk factors is associated with slower decline in Alzheimer disease. Neurology. 2009;73:674–80.Google Scholar