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Isolated Angiitis of the Central Nervous System in Childhood

Published online by Cambridge University Press:  18 September 2015

D.G. Matsell ,
D.L. Keene ,
C. Jimenez  and
P. Humphreys
D.G. Matsell
Affiliation:
Department of Pediatrics, Neurology Service, and Department of Pathology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa
D.L. Keene*
Affiliation:
Department of Pediatrics, Neurology Service, and Department of Pathology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa
C. Jimenez
Affiliation:
Department of Pediatrics, Neurology Service, and Department of Pathology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa
P. Humphreys
Affiliation:
Department of Pediatrics, Neurology Service, and Department of Pathology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa
*
Children's Hospital of Eastern Ontario, Neurology Service, 401 Smyth Road, Ottawa, Ontario, Canada K1H 8L1
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Abstract:

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Isolated angiitis of the central nervous system, a rare inflammatory condition of the nervous system, characterized by vasculitis of the small vessels, has not, to the best of our knowledge, been described in childhood. It usually presents with a diversity of neurological symptoms in the fifth to eighth decades of life. We reviewed the case of an 8 year old male with autopsy proven isolated cerebral angiitis, to encourage the consideration of this disorder in children; and to emphasize the lack of sensitivity of present modalities of neurological investigation in the diagnosis.

Résumé:

RÉSUMÉ:

L'angéite isolée du système nerveux central, une affection inflammatoire rare du système nerveux, caractérisée par une vasculite des petits vaisseaux, n'a jamais, au meilleur de notre connaissance, été décrite dans l'enfance. Elle se présente avec divers symptômes neurologiques entre la cinquième et la huitième décade de vie. Nous avons revu le cas d'un jeune garçon de 8 ans avec angéite cérébrale isolée prouvée à l'autopsie, pour inciter les cliniciens à considérer cette maladie chez les enfants et pour souligner le manque de sensibilité des modalités actuelles d'investigation neurologique dans ce diagnostic.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 17 , Issue 2 , May 1990 , pp. 151 - 154
Copyright
Copyright © Canadian Neurological Sciences Federation 1990

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