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Environmental Exposures in Elderly Canadians With Parkinson’s Disease

Published online by Cambridge University Press:  18 September 2015

S. Chaturvedi ,
T. Østbye ,
A.J. Stoessl ,
H. Merskey  and
V. Hachinski
S. Chaturvedi
Affiliation:
Department of Clinical Neurological Sciences, University of Western Ontario, London
T. Østbye*
Affiliation:
Department of Epidemiology and Biostatistics, University of Western Ontario, London
A.J. Stoessl
Affiliation:
Department of Clinical Neurological Sciences, University of Western Ontario, London
H. Merskey
Affiliation:
Department of Psychiatry, Faculty of Medicine, University of Western Ontario, London
V. Hachinski
Affiliation:
Department of Epidemiology and Biostatistics, University of Western Ontario, London
*
Department of Epidemiology and Biostatistics, Kresge Building, University of Western Ontario, London. Ontario, Canada N6A 5CI
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Abstract

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Background

Etiologic hypotheses for Parkinson’s disease have implicated environmental factors, genetic factors, or a combination of the two.

Methods

Data from a survey of elderly Canadians (n = 10,263) with regard to their history of Parkinson’s disease and previous environmental exposures were analyzed. Exposure to various environmental factors was compared between 87 patients with Parkinson’s disease and 2070 elderly controls without Parkinson’s disease.

Results

Exposure to plastic resins (OR (odd ratio) = 8.79), epoxy resins (OR = 6.94), glues (OR = 4.26), paints (OR = 3.84), and petroleum (OR = 2.30) products was significantly (p < 0.05) associated with Parkinson’s disease.

Conclusion

These substances deserve further exploration with respect to the possible development of parkinsonism.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 22 , Issue 3 , August 1995 , pp. 232 - 234
Copyright
Copyright © Canadian Neurological Sciences Federation 1995

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