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Effects of Venesection on Cerebral Function in Chronic Lung Disease

Published online by Cambridge University Press:  18 September 2015

R. Bornstein ,
D. Menon ,
E. York ,
B. Sproule  and
C. Zak
R. Bornstein*
Affiliation:
Division of Psychology, University of Alberta Hospital and the Divisions of Biomedical Engineering and Pulmonary Medicine, University of Alberta, Edmonton, Canada
D. Menon
Affiliation:
Division of Psychology, University of Alberta Hospital and the Divisions of Biomedical Engineering and Pulmonary Medicine, University of Alberta, Edmonton, Canada
E. York
Affiliation:
Division of Psychology, University of Alberta Hospital and the Divisions of Biomedical Engineering and Pulmonary Medicine, University of Alberta, Edmonton, Canada
B. Sproule
Affiliation:
Division of Psychology, University of Alberta Hospital and the Divisions of Biomedical Engineering and Pulmonary Medicine, University of Alberta, Edmonton, Canada
C. Zak
Affiliation:
Division of Psychology, University of Alberta Hospital and the Divisions of Biomedical Engineering and Pulmonary Medicine, University of Alberta, Edmonton, Canada
*
Division of Psychology, University of Alberta Hospital, 112 Street and 83 Avenue, Edmonton, Alberta, Canada, T6G 2B7
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Summary:

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Regional cerebral blood flow measurements and neuropsychological testing were conducted before and after venesection on 6 patients with polycythemia secondary to chronic obstructive pulmonary disease. Venesection resulted in lowered viscosity and hematocrit, and an accompanying improvement in cerebral perfusion and mental function. Blood flow was significantly increased in the left cerebral hemisphere following phlebotomy, and there was significant improvement in sensory I mental function. Cerebral function would appear to be related to blood flow alterations influenced by the viscosity of the blood.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 7 , Issue 4 , November 1980 , pp. 293 - 296
Copyright
Copyright © Canadian Neurological Sciences Federation 1980

References

REFERENCES

Bornstein, R.A., Benoit, B.G. and Trites, R.L. (in preparation). The effects of hematocrit on changes in neuropsychological performance following carotid endarterectomy.Google Scholar
Dormandy, J.A. (1970). Clinical significance of blood viscosity. Ann. R. Coll. Surg. Engl. 47: 211–218.Google ScholarPubMed
Grant, I., Heaton, R.K. and McSweeney, A.J.et al (1980). Brain dysfunction in COPD. Chest 77: 2 (Suppl.): 308–309.Google Scholar
Gur, R.C., Packer, I.K. and Hungerbuhler, J.P.et al (1980). Differences in the distribution of gray and white matter in human cerebral hemispheres. Science 207: 1226–1228.CrossRefGoogle ScholarPubMed
Menon, D. and Weir, B. (1979). Evaluation of cerebral blood flow in arteriovenous malformations by the Xenon 133 inhalation method. Can. J. Neurol. Sci. 6: 411–417.CrossRefGoogle ScholarPubMed
Reitan, R.M. and Davison, L.A. (1974). Clinical Neuropsychology: Current Status and Applications. John Wiley and Sons, New York.Google Scholar
Risberg, J., Ali, Z. and Wilson, E.M.et al (1975). Regional cerebral blood flow by 133Xenon inhalation. Stroke 6: 142–148.CrossRefGoogle Scholar
Thomas, D.J., Duboulay, G.H. and Marshall, J.et al (1977). Effects of hematocrit on cerebral blood flow in man. Lancet 2: 941–943.CrossRefGoogle ScholarPubMed
Willison, J.R., Thomas, D.J. and Duboulay, G.H.et al (1980). Effect of high hematocrit on alertness. Lancet 2: 846–848.CrossRefGoogle Scholar
Wintrobe, M.M. (1974). Clinical Hematology. Lea and Febiger, Phil.Google Scholar
York, E.L., Jones, R.L. and Menon, D.et al (1980). Effects of secondary polycythemia on cerebral blood flow in chronic obstructive pulmonary disease, (in press) Amer. Rev. Respirât. Dis. 121: 813–818.Google ScholarPubMed