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CSF Electrophoresis: An Adaptation Using Cellulose Acetate for the Identification of Oligoclonal Banding

Published online by Cambridge University Press:  18 September 2015

D.W. Paty ,
M. Donnelly  and
M.E. Bernardo
D.W. Paty*
Affiliation:
Departments of Clinical Neurological Sciences, Instructional Resources and Clinical Biochemistry, University Hospital, University of Western Ontario, London, Ontario
M. Donnelly
Affiliation:
Departments of Clinical Neurological Sciences, Instructional Resources and Clinical Biochemistry, University Hospital, University of Western Ontario, London, Ontario
M.E. Bernardo
Affiliation:
Departments of Clinical Neurological Sciences, Instructional Resources and Clinical Biochemistry, University Hospital, University of Western Ontario, London, Ontario
*
Department of Clinical Neurological Sciences, University Hospital, P.O. Box 5339, H3A 2B4, Postal Station A., London, Ontario N6A 5A5, Canada.
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Summary:

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An adaptation of cellulose acetate electrophoresis for studying concentrated cerebrospinal fluid is described. Two hundred and twenty-one patients have been studied, and the specificity for multiple sclerosis and sub-acute sclerosing panencephalitis is discussed. This has been positive for oligoclonal banding (OB) in 79% of patients with clinically definite multiple sclerosis.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 5 , Issue 3 , August 1978 , pp. 297 - 299
Copyright
Copyright © Canadian Neurological Sciences Federation 1978

References

REFERENCES

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