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The Carbohydrate and Caloric Content of Concomitant Medications for Children with Epilepsy on the Ketogenic Diet

Published online by Cambridge University Press:  02 December 2014

Denis Lebel ,
Caroline Morin ,
Nathalie Achim ,
Micheline Laberge  and
Lionel Carmant
Denis Lebel
Affiliation:
Department of Pharmacy, Hôpital Ste-Justine, University of Montreal, Montreal, QC Canada
Caroline Morin
Affiliation:
Department of Pharmacy, Hôpital Ste-Justine, University of Montreal, Montreal, QC Canada
Nathalie Achim
Affiliation:
Department of Pharmacy, Hôpital Ste-Justine, University of Montreal, Montreal, QC Canada
Micheline Laberge
Affiliation:
Department of Pediatrics, Hôpital Ste-Justine, University of Montreal, Montreal, QC Canada
Lionel Carmant
Affiliation:
Department of Pediatrics, Hôpital Ste-Justine, University of Montreal, Montreal, QC Canada
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Abstract

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Background:

The ketogenic diet for children with refractory epilepsy requires a strict control of the amount of ingested carbohydrates. This can be altered by medication prescribed for the epileptic syndrome or for intercurrent illnesses. The goal of this paper is to compile the carbohydrate and caloric content of commonly used medications in this population.

Methods:

We compiled a list of frequently used medications with the help of Canadian manufacturers and the Compendium of Pharmaceuticals and Specialties. We also tested a worst case scenario calculation based on the weight of the tablet.

Results:

We list the carbohydrate and caloric content of 790 medications studied. Our worst case scenario gives an over-estimate in all cases, making adjustments based on this calculation in an emergency setting safe.

Conclusion:

We propose this list as a tool for physicians, dietitians, nurses and pharmacists. The list can easily be adjusted, based on local practices and reviewed periodically.

Résumé:

RÉSUMÉ:

Le contenu en hydrates de carbone et en calories des médicaments concomitants chez les enfants épileptiques suivant la diète cétogène.

Introduction:

La diète cétogène chez les enfants dont l'épilepsie est résistante au traitement demande un contrôle strict de la quantité d'hydrates de carbone ingérée qui peut être influencée par la médication prescrite pour le syndrome épileptique ou pour une maladie intercurrente. Le but de cet article est de compiler le contenu en hydrates de carbone et en calories de médicaments d'usage courant dans cette population.

Méthodes:

Nous avons compilé une liste des médicaments d'usage courant avec l'aide de manufacturiers Canadiens et du Compendium des produits et spécialités pharmaceutiques. Nous avons également testé un calcul basé sur le poids du comprimé qui tenait compte de la pire situation possible.

Résultats:

Nous avons dressé une liste du contenu en hydrates de carbone et en calories de 790 médicaments. Notre calcul selon la pire situation surestime dans tous les cas, ce qui assure la sécurité de l'ajustement basé sur ce calcul en situation d'urgence.

Conclusions:

Nous proposons cette liste comme outil pour les médecins, les diététistes, les infirmières et les pharmaciens. La liste peut facilement être ajustée selon les pratiques locales et révisée périodiquement.

Type
Original Article
Information
Canadian Journal of Neurological Sciences , Volume 28 , Issue 4 , November 2001 , pp. 322 - 340
Copyright
Copyright © The Canadian Journal of Neurological 2001

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