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Absence of HTLV-I and HTLV-II Proviral Genome in the Brains of Patients with Multiple Sclerosis and Amyotrophic Lateral Sclerosis

Published online by Cambridge University Press:  18 September 2015

G.A. Dekaban ,
A.J. Hudson  and
G.P.A. Rice
G.A. Dekaban
Affiliation:
Department of Clinical Neurological Sciences, University of Western Ontario, London
A.J. Hudson
Affiliation:
Department of Clinical Neurological Sciences, University of Western Ontario, London
G.P.A. Rice*
Affiliation:
Department of Clinical Neurological Sciences, University of Western Ontario, London
*
INS Department, University Hospital, 339 Windermere Road, London, Ontario, Canada N6A 5A5
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Abstract:

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Previous studies have failed to provide serological evidence to incriminate a retroviral infection in the cause of multiple sclerosis. Gene amplification techniques have also failed to identify retroviral footprints in DNA from peripheral blood leukocytes. Here we provide evidence that proviral DNA of HTLV-I and HTLV-II is not found in the central nervous system tissues of patients with multiple sclerosis, patients with amyotrophic lateral sclerosis and controls.

Type
Articles
Information
Canadian Journal of Neurological Sciences , Volume 19 , Issue 4 , November 1992 , pp. 458 - 461
Copyright
Copyright © Canadian Neurological Sciences Federation 1992

References

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