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Tissue plasminogen activator for acute ischemic stroke: Is the CAEP Position Statement too negative?

Published online by Cambridge University Press:  21 May 2015

Jerome R. Hoffman
Jerome R. Hoffman*
Affiliation:
Professor of Medicine/Emergency Medicine, UCLA School of Medicine, Los Angeles, Calif
*
UCLA Emergency Medicine Center, 924 Westwood Blvd., Ste. 300, Los Angeles CA 90077; [email protected]

Extract

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Adapting information from research to clinical practice can be difficult, and we are often forced to decide whether benefits reported in selected trials are adequate to justify widespread application of the intervention studied. This is particularly problematic when the “evidence” is scanty, the degree of benefit apparently small (if real), and the treatment potentially dangerous. In addition, it is always important to consider whether community physicians can replicate the success described in research studies, which are typically performed by experts working in the controlled setting of a well-funded study.

Type
Controversies • Controverses
Information
Canadian Journal of Emergency Medicine , Volume 3 , Issue 3 , July 2001 , pp. 183 - 185
Copyright
Copyright © Canadian Association of Emergency Physicians 2001

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