Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-26T21:14:31.137Z Has data issue: false hasContentIssue false

Measures of association: an overview with examples from Canadian emergency medicine research

Published online by Cambridge University Press:  21 May 2015

Andrew Worster*
Affiliation:
Research Division of Emergency Medicine, Hamilton Health Sciences Corporation, and McMaster University, Hamilton, Ont
Brian H. Rowe
Affiliation:
Division of Emergency Medicine and Department of Public Health Sciences, University of Alberta, and Capital Health Authority, Edmonton, Alta
*
Department of Emergency Medicine, Hamilton Health Sciences Corporation, 237 Barton St. E, Hamilton ON L8N 3Z5; 905 521-2100 x73136, fax 905 527-7051, [email protected]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The authors of studies often report their results using abbreviated terms such as RR, OR, ARR, RRR and NNT. These terms are quantities that express the strength of association between the dependent and independent variables and are collectively referred to as measures of association. The similarity between these measures and the multiple terms by which each is referred can be confusing. The purpose of this article is to explain in a straightforward manner the purpose, derivation, and limitations of some of the more commonly used categorical measures of association, including relative risk, odds ratio, absolute and relative risk reduction and number needed to treat, using results from recent emergency medicine studies published by Canadian researchers.

Type
Methodology: The Science of EM • Méthodologie: Science de la MU
Copyright
Copyright © Canadian Association of Emergency Physicians 2001

References

1.Rowe, BH, Bota, GW, Fabris, L, Therrien, SA, Milner, RA, Jacono, J.Inhaled budesonide in addition to oral steroids to prevent asthma relapse following discharge from the emergency department: a randomized controlled trial. JAMA 1999;281:211926.CrossRefGoogle ScholarPubMed
2.Last, JM.A dictionary of epidemiology. 3rd ed. New York: Oxford University Press; 1995.Google Scholar
3.McKibbon, A, Eady, A, Marks, S.PDQ: Evidence-based principles and practice. Hamilton (ON): BC Decker Inc.; 1999.Google Scholar
4.Streiner, DL, Norman, GR.PDQ: Epidemiology. 2nd ed. St. Louis: Mosby; 1996.Google Scholar
5.Jaeschke, R, Guyatt, G, Shannon, H, Walter, S, Cook, D, Heddle, N.Basic statistics for clinicians. 3. Assessing the effects of treatment: measures of association. CMAJ 1995;152(3):3517.Google ScholarPubMed
6.Laupacis, A, Sackett, DL, Roberts, RR.An assessment of clinically useful measures of the consequences of treatment. N Engl J Med 1988;318(26):172833.CrossRefGoogle ScholarPubMed
7.Jaeschke, R, Guyatt, GH, Sackett, DL.Users’ guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA 1994;271(1):5963.Google Scholar
8.Lang, TA, Secic, M.How to report statistics in medicine: annotated guidelines for authors, editors, and reviewers. Philadelphia: American College of Physicians; 1997.CrossRefGoogle Scholar
9.Stiell, IG, Wells, GA, Field, BJ, Spaite, DW, De Maio, VJ, Ward, R, et al, for the OPALS Study Group. Improved out-of-hospital cardiac arrest survival through the inexpensive optimization of an existing defibrillation program: OPALS study phase II. Ontario Prehospital Advanced Life Support. JAMA 1999;281:117581.CrossRefGoogle ScholarPubMed
10.Morrison, LJ, Verbeek, PR, McDonald, A, Sawadsky, B: A metaanalysis of prehospital thrombolysis and the effect on mortality in acute myocardial infarction. JAMA 2000;283:268692.Google Scholar
11.Linde, K, Jobst, KA.Homeopathy for chronic asthma [Cochrane review]. In: The Cochrane Library, Issue 1, 2001. Oxford: Update Software.Google Scholar