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Canadian Association of Emergency Physicians Sepsis Guidelines: the optimal management of severe sepsis in Canadian emergency departments

Published online by Cambridge University Press:  21 May 2015

Robert S. Green ,
Dennis Djogovic ,
Sara Gray ,
Daniel Howes ,
Peter G. Brindley ,
Robert Stenstrom ,
Edward Patterson ,
David Easton  and
Jonathan S. Davidow
Robert S. Green*
Affiliation:
Department of Emergency Medicine and the Division of Critical Care Medicine, Department of Internal Medicine, Dalhousie University, Halifax, NS
Dennis Djogovic
Affiliation:
Department of Emergency Medicine, University of Alberta, Edmonton, Alta.
Sara Gray
Affiliation:
Division of Emergency Medicine, University of Toronto, and Emergency Medicine & Intensive Care Medicine, St. Michael's Hospital, Toronto, Ont.
Daniel Howes
Affiliation:
Emergency Medicine and Critical Care, Queen's University, and the Department of Emergency Medicine, Kingston General Hospital, Kingston, Ont.
Peter G. Brindley
Affiliation:
Department of Emergency Medicine, University of Alberta, Edmonton, Alta.
Robert Stenstrom
Affiliation:
Providence Health Care and the Department of Emergency Medicine, St. Paul's Hospital, Vancouver, BC
Edward Patterson
Affiliation:
Departments of Internal Medicine and Emergency Medicine, Regina Qu'Appelle Health Region and the University of Saskatchewan, Regina, Sask.
David Easton
Affiliation:
Department of Emergency Medicine, Health Sciences Centre, Winnipeg, Man.
Jonathan S. Davidow
Affiliation:
Department of Emergency Medicine, University of Alberta, Edmonton, Alta.
*
CAEP Critical Care Interest Group; 1278 Tower Rd., Rm. 349, Bethune Bldg., Halifax NS B3H 2Y9; [email protected]

Abstract

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Introduction:

Optimal management of severe sepsis in the ED has evolved rapidly. The purpose of these guidelines is to review key management principles for Canadian emergency physicians, utilizing an evidence-based grading system.

Methods:

Key areas in the management of septic patents were determined by members of the CAEP Critical Care Interest Group (C4). Members of C4 were assigned a question to be answered after literature review, based on the Oxford grading system. After completion, each section underwent a secondary review by another member of C4. A tertiary review was conducted by additional external experts, and modifications were determined by consensus. Grading was based on peer-reviewed publications only, and where evidence was insufficient to address an important topic, a “practice point” was provided based on group opinion.

Results:

The project was initiated in 2005 and completed in December 2007. Key areas which were reviewed include the definition of sepsis, the use of invasive procedures, fluid resuscitation, vasopressor/inotrope use, the importance of culture acquisition in the ED, antimicrobial therapy and source control. Other areas reviewed included the use of corticosteroids, activated protein C, transfusions and mechanical ventilation.

Conclusion:

Early sepsis management in the ED is paramount for optimal patient outcomes. The CAEP Critical Care Interest Group Sepsis Position Statement provides a framework to improve the ED care of this patient population.

Keywords

sepsissevere sepsisseptic shockemergency medicineguidelinesresuscitation
Type
CAEP Update • Mise à jour de l’ACMU
Information
Canadian Journal of Emergency Medicine , Volume 10 , Issue 5 , September 2008 , pp. 443 - 459
Copyright
Copyright © Canadian Association of Emergency Physicians 2008

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