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A possible genetic method for the control of insect pests, with special reference to tsetse flies (Glossina spp.)

Published online by Cambridge University Press:  10 July 2009

C. F. Curtis
C. F. Curtis
Affiliation:
Tsetse Rescarch Laboratory, University of Bristol, School of Veterinary Science, Langford, near Bristol, England
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Extract

The use of chromosome translocations for the control of pests, with particular reference to Glossina, is proposed. A translocation arises if two non-homologous chromosomes in the same cell undergo breakage and the fragments re-join with the wrong partners. At meiosis in an individual heterozygous for a translocation, gamete nuclei with several different combinations of chromosomes are produced. Some of these are diploid for one part and lack completely another part of the normal chromosome set; when such unbalanced gametes fertilise normal gametes inviable embryos are produced. It has been found in a number of organisms that about half the gametes of translocation heterozygotes are of the unbalanced type and such heterozygotes are described as semi-sterile. If an individual inherits the same translocation from both parents it is described as a translocation homozygote; this is often inviable but, if not, its fertility is usually normal.

Adult males of G. austeni Newst. have been irradiated and each of their progeny are being screened for the occurrence of semi-sterility. Any individuals found to be semi-sterile would probably be translocation heterozygotes and their progeny will be inbred to try to produce a viable stock, homozygous for a translocation. If this can be done, large numbers of such translocation homozygotes could be reared and released into a wild population, where matings with wild types would produce heterozygotes, and hence a reduction in the fertility of the population.

Using simple assumptions, the effects of releasing translocation homozygotes were computed. Provided the numbers released were such that the translocation frequency approached the optimum value of 50 per cent., the reduction in population fertility would be prolonged for many generations after the releases had finished. It is shown that it would be more efficient to release the translocation homozygotes at successive generations rather than all at once and that the homozygotes released could with advantage be of both sexes. For this reason, and because of the prolonged effect of releases of translocations, it is concluded that the number of individuals that would have to be reared to achieve a given result by the translocation method might be considerably less than if the sterile-male method was used. However, the reduction in population fertility at each generation that can be achieved with the translocation method is limited, and the method would therefore be ineffective against populations whose size was strongly buffered by density-dependent factors.

Type
Research Paper
Information
Bulletin of Entomological Research , Volume 57 , Issue 4 , June 1968 , pp. 509 - 523
Copyright
Copyright © Cambridge University Press 1968

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References

Burnham, C. R. (1962). Discussion in Cytogenetics, Chapter IV.—Minneapolis, Burgess.Google Scholar
Buxton, P. A. (1955). The natural history of tsetse flies.—Mem. Lond. Sch. Hyg. trop. Med. no. 10, 816 pp. London, H. K. Lewis.Google Scholar
Carter, T. C., Lyon, M. F. & Phillips, R. J. S. (1955). Gene-tagged chromosome translocations in eleven stocks of mice.—J. Genet. 53 pp. 154–166.CrossRefGoogle Scholar
Dame, D. A., Dean, G. J. W. & Ford, J. (1965). Investigations of the sterile male technique with Glossina morsitans.—10th Mtg. int. sci. Comm. Trypanosom. Res. 1964. pp. 93–96.Google Scholar
Dame, D. A. & Ford, H. R. (1966). Effect of the chemosterilant tepa on Glossina morsitans Westw.—Bull. ent. Res. 56 pp. 649–658.Google Scholar
Dobzhansky, T. (1951). Genetics and the origin of species. 3rd edn, 364 pp.—New York, Columbia Univ. Pr.Google Scholar
Glasgow, J. P. (1963). The distribution and abundance of tsetse.—241 pp. Oxford &c., Perg amon Pr.Google Scholar
Glass, H. B. (1935). A study of factors influencing chromosomal segregation in translocations of Drosophila melanogaster.—Univ. of Missouri Coll. of Agric. Res. Bull. 231, 28 pp.Google Scholar
Herskowitz, I. H. (1957). A relationship between translocation frequency and age at fertilization for sperm X-rayed in females of D. melanogaster.—Genetics 42 pp. 375–376.Google Scholar
Hocking, K. S., Parr, H. C. M., Yeo, D. & Anstey, D. (1953). Aircraft applications of insecticides in East Africa. IV.—Bull. ent. Res. 44 pp. 627–631.Google Scholar
Jordan, A. M., Nash, T. A. M. & Boyle, J. A. (1967). The rearing of Glossina austeni Newst., with lop-eared rabbits as hosts. I.—Efficacy of the method.—Ann. trop. Med. Parasit. 61 pp. 182–188.CrossRefGoogle ScholarPubMed
Knipling, E. F. (1960). Control of screwworm fly by atomic radiation. [In] American Association for the Advancement of Science. Section O on Agriculture Biological and chemical control of plant and animal pests; a symposium, pp. 169–182.Google Scholar
Knipling, E. F. (1963). Potential role of the sterility principle for tsetse fly eradication.—W.H.O/Vector Control/27, 17 pp.Google Scholar
LaChance, L. E. & Knipling, E. F. (1962). Control of insect populations through genetic manipulations.—Ann. ent. Soc. Am. 55 pp. 515–520.Google Scholar
Potts, W. H. (1958). Sterilization of tsetse flies (Glossina) by gamma irradiation.—Ann. trop. Med. Parasit. 52, pp. 484–499.CrossRefGoogle ScholarPubMed
Snell, G. D. (1946). An analysis of translocations in the mouse.—Genetics 31 pp. 157–180.CrossRefGoogle ScholarPubMed
Wright, S. (1941). On the probability of fixation of reciprocal translocations.—Am. Nat. 75 pp. 513–522.Google Scholar