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Avermectins in insect control and biology: a review

Published online by Cambridge University Press:  10 July 2009

L. Strong  and
T. A. Brown
L. Strong
Affiliation:
Department of Zoology, The University, Bristol, BS8 1UG, UK
T. A. Brown
Affiliation:
Department of Zoology, The University, Bristol, BS8 1UG, UK
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Abstract

In a variety of laboratory and field experiments, avermectins have been tested against some 84 species of insects in ten orders, most of which are pests of livestock or horticultural crops or are of general nuisance value. This work is reviewed, comparing doses used, methods of application, and responses of the insects. Avermectins (abamectin and ivermectin) are toxic to almost all insects examined, although tolerance varies and death can be uncommonly slow, taking 24 h to 30 days. There is a marked absence of information on physiological processes that are affected by the pesticides, although at the cellular level they are thought to disrupt receptors for y-aminobutyric acid and glutamic acid in the central nervous system and muscular system. At high doses, treated insects are progressively immobilized, and although initially many can move when stimulated, this ability becomes lost. Some show a disturbed water balance and become distended with fluid, while others show disruption of moulting and metamorphosis. Feeding inhibition is commonly observed at sub-lethal doses. Avermectins affect many aspects of reproduction including mating behaviour, egg development, oviposition and egg hatching. The possibility is raised that these diverse disturbances are not all due to disruption of neuromuscular or central nervous system synapses, and the need for work in this area is stressed. Field studies have shown ivermectin to be most valuable in eradicating insect pests of livestock, but the use of abamectin against horticultural pests has produced less impressive results. The limited work on non-target species is discussed, and attention is drawn to some possible environmental consequences of excreted ivermectin on dung-breeding insects.

Type
Review Article
Information
Bulletin of Entomological Research , Volume 77 , Issue 3 , September 1987 , pp. 357 - 389
Copyright
Copyright © Cambridge University Press 1987

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References

Agee, H. R. (1985 a). Neurobiology of the bollworm moth: effects of abamectin on neural activity and on sensory systems.—J. agric. Ent. 2, 325–336.Google Scholar
Agee, H. R. (1985 b). Neurobiology of the bollworm moth: responses of neurons in the central nervous system to abamectin.—J. agric. Ent. 2, 337–344.Google Scholar
Ali, A. & Nayar, J. K. (1985). Activity of an avermectin insecticide, abamectin (MK-936), against mosquitoes and chironomid midges in the laboratory.—J. Am. Mosquito Control Ass. 1, 384–386.Google ScholarPubMed
Alva-Valdes, R., Wallace, D. H., Holste, J. E., Eggerton, J. R., Cox, J. L., Wooden, J. W. & Barrick, R. A. (1986). Efficacy of ivermectin in a topical formulation against induced gastrointestinal and pulmonary nematode infections, and naturally acquired grubs and lice in cattle.—Am. J. vet. Res. 47, 2389–2392.Google Scholar
Anderson, J. R. (1966). Recent developments in the control of some arthropods of public health and veterinary importance.—Bull. ent. Soc. Am. 12, 342–348.Google Scholar
Anderson, J. R., Merritt, R. W. & Loomis, E. C. (1984). The insect-free cattle dropping and its relationship to increased dung fouling of rangeland pastures.—J. econ. Ent. 77, 133–141.CrossRefGoogle Scholar
Anderson, T. E., Babu, J. R., Dybas, R. A. & Mehta, H. (1986). Avermectin B1: ingestion and contact toxicity against Spodoptera eridania and Heliothis virescens (Lepidoptera: Noctuidae) and potentiation by oil and piperonyl butoxide.—J. econ. Ent. 79, 197–201.CrossRefGoogle Scholar
Apperson, C. S., Powell, E. E. & Browne, M. (1984). Efficacy of individual mound treatments of MK-936 and Amdro against the red imported fire ant (Hymenoptera: Formicidae).—J. Georgia entomol. Soc. 19, 508–516.Google Scholar
Argenté, G. & Hillion, E. (1984). Utilisation de petites doses d'ivermectine pour le traitement préventif de l'hypodermose bovine.—Point Vétérinaire 16, 614–618.Google Scholar
Badiola, C., Schindler, P. & Tassi, P. (1982). Control de la hipodermosis bovina con ivermectina.—Revta ibér. Parasit. Vol. Extra, 555–558.Google Scholar
Baker, T. C., van Vorhis Key, S. E. & Gaston, L. K. (1985). Bait-preference tests for the Argentine ant (Hymenoptera: Formicidae).—J. econ. Ent. 78, 1083–1088.CrossRefGoogle Scholar
Bariola, L. A. (1984). Pink bollworms (Lepidoptera: Gelechiidae): effects of low concentrations of selected insecticides on mating and fecundity in the laboratory.—J. econ. Ent. 77, 1278–1282.CrossRefGoogle Scholar
Bariola, L. A. & Lingren, P. D. (1984). Comparative toxicities of selected insecticides against pink bollworm (Lepidoptera: Gelechiidae) moths.—J. econ. Ent. 77, 207–210.CrossRefGoogle Scholar
Barth, D. (1983). Ivomec, ein neues Antiparasitikum mit endo- und ektoparasitizider Wirkung.—pp. 95–100a in Symposium Parasitosen der Wiederkauer, Techlenburg.Google Scholar
Barth, D. & Brokken, E. S. (1980). The activity of 22,23-dihydroavermectin B1 against the pig louse, Haematopinus suis (L.).—Vet. Rec. 106, 388.CrossRefGoogle Scholar
Barth, D. & Preston, J. M. (1985). Efficacy of ivermectin against the sucking louse Solenopotes capillatus.—Vet. Rec. 116, 267.CrossRefGoogle ScholarPubMed
Barth, D. & Sutherland, I. H. (1980). Investigations of the efficacy of ivermectin against ectoparasites in cattle.—Zentbl. Bakt. ParasitKde Abt. No. 57, 267–319.Google Scholar
Beach, R. M. & Todd, J. W. (1985). Toxicity of avermectin to larva and adult soybean looper (Lepidoptera: Noctuidae) and influence on larva feeding and adult fertility and fecundity.—J. econ. Ent. 78, 1125–1128.CrossRefGoogle Scholar
Bello, T. R. & Norfleet, C. M. (1981). Critical antiparasitic efficacy of ivermectin against equine parasites.—Equine vet. Sci. 1, 14–17.CrossRefGoogle Scholar
Benz, G. W. (1985). Animal health applications of ivermectin.—Southwestern Entomologist Suppl. No. 7, 43–50.Google Scholar
Bry, R. E. & Lang, J. H. (1984). Avermectin B1a: effectiveness against three species of fabric insects.—J. Georgia entomol. Soc. 19, 523–532.Google Scholar
Bull, D. L. (1985). Environmental fate of ivermectin.—Southwestern Entomologist Suppl. No. 7, 2–10.Google Scholar
Bull, D. L. (1986). Toxicity and pharmacodynamics of avermectin in the tobacco budworm, corn earworm, and fall armyworm (Noctuidae: Lepidoptera).—J. agric. Fd Chem. 34, 74–78.CrossRefGoogle Scholar
Bull, D. L., Ivie, G. W., MacConnell, J. G., Gruber, V. F., Ku, C. C., Arison, B. H., Stevenson, J. M. & VandenHeuvel, W. J. A. (1984). Fate of avermectin B1a in soil and plants.—J. agric. Fd Chem. 32, 94–102.CrossRefGoogle Scholar
Burts, E. C. (1985). SN 72129 and avermectin B1, two new pesticides for control of pear psylla, Psylla pyricola (Homoptera: Psyllidae).—J. econ. Ent. 78, 1327–1330.CrossRefGoogle Scholar
Campbell, C. A. M. & Easterbrook, M. A. (1985). Insecticides/acaricides for control of pear sucker and rust mite.—Ann. appl. Biol. 106 (Suppl. No. 6), 18–19.Google Scholar
Campbell, W. C. (1981). An introduction to the avermectins.—N.Z. vet. J. 29, 174–178.CrossRefGoogle Scholar
Campbell, W. C. (1985). Ivermectin: an update.—Parasit. Today 1, 10–16.CrossRefGoogle ScholarPubMed
Campbell, W. C. (1986). Letter in Parasit. Today 2, 75.Google Scholar
Campbell, W. C. and Benz, G. W. (1984). Ivermectin: a review of efficacy and safety.—J. vet. Pharmac. Ther. 7, 1–16.CrossRefGoogle ScholarPubMed
Campbell, W. C., Fisher, M. H., Stapley, E. O., Albers-Schönberg, G. & Jacob, T. A. (1983). Ivermectin: a potent new antiparasitic agent.—Science, N. Y. 221, 823–828.CrossRefGoogle ScholarPubMed
Chamberlain, W. F. (1982 a). Evaluation of toxicants against the secondary screwworm, 1978.—Insecticide & Acaricide Tests 7, 255.CrossRefGoogle Scholar
Chamberlain, W. F. (1982 b). Evaluation of insecticides for control of biting lice, 1979–1980.—Insecticide & Acaricide Tests 7, 256–257.CrossRefGoogle Scholar
Chamberlain, W. F. (1982 c). Laboratory evaluation of IGR's and toxicants against the larvae of the oriental rat flea, 1977–1980.—Insecticide & Acaricide Tests 7, 256.CrossRefGoogle Scholar
Chandler, L. D. (1985). Response of Liriomyza trifolii (Burgess) to selected insecticides with notes on hymenopterous parasites.—Southwestern Entomologist 10, 228–235.Google Scholar
Cochran, D. G. (1985). Mortality and reproductive effects of avermectin B1 fed to German cockroaches.—Entomologia exp. appl. 37, 83–88.CrossRefGoogle Scholar
Craig, T. M. & Kunde, J. M. (1981). Controlled evaluation of ivermectin in Shetland ponies.—Am. J. vet. Res. 42, 1422–1429.Google ScholarPubMed
de Azambuja, P., Gomes, J. E. P. L., Lopes, F. & Garcia, E. S. (1985). Efficacy of ivermectin against the bloodsucking insect, Rhodnius prolixus (Hemiptera, Triatominae).—Mems Inst. Oswaldo Cruz 80, 439–442.CrossRefGoogle ScholarPubMed
Dipietro, J. A., Todd, K. S., Lock, T. F. & McPherron, T. A. (1982). Anthelminthic efficacy of ivermectin given intramuscularly in horses.—Am. J. vet. Res. 43, 145–148.Google ScholarPubMed
Distelmans, W., D'Haeseleer, F. & Mortelmans, J. (1983). Efficacy of systemic administration of ivermectin against tsetse flies.—Annls Soc. belge Méd. trop. 63, 119–125.Google ScholarPubMed
Drudge, J. H., Lyons, E. T. & Tolliver, S. C. (1984). Controlled tests of activity of ivermectin against natural infections of migratory large strongyles and other internal parasites of equids.—Am. J. vet. Res. 45, 2267–2271.Google ScholarPubMed
Drummond, R. O. (1983). Cattle—Hypoderma lineatum animal systemic insecticide test, 1982.—Insecticide & Acaricide Tests 8, 238.CrossRefGoogle Scholar
Drummond, R. O. (1984). Control of larvae of the common cattle grub (Diptera: Oestridae) with animal systemic insecticides.—J. econ. Ent. 77, 402–406.CrossRefGoogle ScholarPubMed
Drummond, R. O. (1985). Effectiveness of ivermectin for control of arthropod pests of livestock.—Southwestern Entomologist Suppl. No. 7, 34–42.Google Scholar
Dybas, R. A. & Green, A. St.J. (1984). Avermectins: their chemistry and pesticidal activity.—pp. 947–954 in 1984 British Crop Protection Conference. Pests and diseases. Proceedings of a conference held at Brighton Metropole, England, November 19–22, 1984. Vol. 3.—pp. 847–1207. Croydon, UK, Br. Crop Prot. Coun.Google Scholar
Eggerton, J. R., Brokken, E. S., Suhayda, D., Eary, C. H., Wooden, J. W. & Kilgore, R. L. (1981). The antiparasitic activity of ivermectin in horses.—Vet. Parasitol. 8, 83–88.CrossRefGoogle Scholar
Fisher, M. H. & Mrozik, K. H. (1984). The avermectin family of macrolide-like antibiotics.—pp. 553–606 in Omura, S. (Ed.). Macrolide antibiotics.—635 pp. New York, Academic Press.Google Scholar
Gerolt, P. (1983). Insecticides: their route of entry, mechanism of transport and mode of action.—Biol. Rev. 58, 233–274.CrossRefGoogle ScholarPubMed
Glancey, B. M., Lofgren, C. S. & Williams, D. F. (1982). Avermectin B1a: effects on the ovaries of red imported fire ant queens (Hymenoptera: Formicidae).—J. med. Entomol. 19, 743–747.CrossRefGoogle ScholarPubMed
Green, A. St. J.Brown, R. D. & Dybas, R. A. (1984). MK-936, a novel acaricide-insecticide for use on pears.—Bull. SROP 7 (5), 302–317.Google Scholar
Green, A. St. J. & Dybas, R. A. (1984). The control of Liriomyza leafminers and other insect species with avermectin B1.—pp. 1135–1141 in 1984 British Crop Protection Conference. Pests and diseases. Proceedings of a conference held at Brighton Metropole, England, November 19–22, 1984. Vol. 3.—pp. 847–1207. Croydon, UK, Br. Crop Prot. Coun.Google Scholar
Grout, T. G. & Morse, J. G. (1986). Insect growth regulators: promising effects on citrus thrips (Thysanoptera: Thripidae).—Can. Ent. 118, 389–392.CrossRefGoogle Scholar
Guerrero Molina, C. (1986). Compared activity of ivermectin administered subcutaneously and orally in sheep naturally infected with Melophagus ovinus.—Veterinaria, México 17, 41–44.Google Scholar
Hara, A. H. (1986). Effects of certain insecticides on Liriomyza trifolii (Burgess) (Diptera: Agromyzidae) and its parasitoids on chrysanthemums in Hawaii.—Proc. Hawaii. ent. Soc. 26, 65–70.Google Scholar
Horak, I. G., Boomker, J., Kingsley, S. A. & De Vos, V. (1983). The efficacy of ivermectin against helminth and arthropod parasites of impala.—J. South Afr. vet. Assoc. 54, 251–253.Google ScholarPubMed
Hotson, I. K. (1982). The avermectins: a new family of antiparasitic agents.—J. South Afr. vet. Assoc. 53, 87–90.Google ScholarPubMed
Ishaaya, I., Gurevitz, E. & Ascher, K. R. S. (1983). Synthetic pyrethroids and avermectin for controlling the grapevine pests Lobesia botrana, Cryptoblabes gnidiella and Drosophila melanogaster.—Phytoparasitica 11, 161–166.CrossRefGoogle Scholar
Iwata, Y., MacConnell, J. G., Flor, J. E., Putter, I. & Dinoff, T. M. (1985). Residues of avermectin B1a on and in citrus fruits and foliage.—J. agric. Fd Chem. 33, 467–471.CrossRefGoogle Scholar
James, P. S., Picton, J. & Rilk, R. F. (1980). Insecticidal action of the avermectins.—Vet. Rec. 106, 59.CrossRefGoogle Scholar
Johnson, A. W. (1985). Abamectin for tobacco insect control.—Tob. Sci. 29, 135–138.Google Scholar
Karesh, W. B. & Robinson, P. T. (1985). Ivermectin treatment of lice infestations in two elephant species.—J. Am. vet. med. Ass. 187, 1235.Google ScholarPubMed
Kay, I. T. & Turnbull, M. D. (1985). Synthetic approaches to the avermectin toxophore.—pp. 229–244in Janes, N. F. (Ed.). Recent advances in the chemistry of insect control.—322 pp. London, R. Soc. Chem. (Spec. Publ. No. 53).Google Scholar
Klei, T. R. & Torbert, B. J. (1980). Efficacy of ivermectin (22,23-dihydroavermectin B1) against gastro-intestinal parasites in ponies.—Am. J. vet. Res. 41, 1747–1750.Google Scholar
Langley, P. A. & Roe, J. M. (1984). Ivermectin as a possible control agent for the tsetse fly, Glossina morsitans.—Entomologia exp. appl. 36, 137–143.CrossRefGoogle Scholar
Leaning, W. H. D. (1984). Ivermectin as an antiparasitic agent in cattle.—Mod. vet. Pract. 65, 669–672.Google ScholarPubMed
Lofgren, C. S. & Williams, D. F. (1982). Avermectin B1a: highly potent inhibitor of reproduction by queens of the red imported fire ant (Hymenoptera: Formicidae).—J. econ. Ent. 75, 798–803.CrossRefGoogle ScholarPubMed
Lyons, E. T., Drudge, J. H. & Tolliver, S. C. (1980). Antiparasitic activity of ivermectin in critical tests in equids.—Am. J. vet. Res. 41, 2069–2072.Google ScholarPubMed
Maia, A. A. M. & Guimarães, M. P. (1986). Uso da ivermectina no controle de larvas de Dermatobia hominis (Linnaeus Jr, 1781) (Diptera: Cuterebridae) em bovinos de corte.—Arquivo Bras. Med. Vet. Zootecnia 38, 57–64.Google Scholar
Meleney, W. D. (1982). Control of psoroptic scabies on calves with ivermectin.—Am. J. vet. Res. 43, 329–331.Google ScholarPubMed
Merritt, R. W. & Anderson, J. R. (1977). The effects of different pasture and rangeland ecosystems on the annual dynamics of insects in cattle droppings.—Hilgardia 45, 31–71.CrossRefGoogle Scholar
Meyer, J. A., Simco, J. S. & Lancaster, J. L. Jr. (1980). Control of face fly larval development with ivermectin, MK-933.—Southwestern Entomologist 5, 207–209.Google Scholar
Miller, J. A., Chamberlain, W. F. & Oehler, D. D. (1985). Methods for control of the Angora goat biting louse.—Southwestern Entomologist 10, 181–184.Google Scholar
Miller, J. A., Drummond, R. O. & Oehler, D. D. (1983). A sustained release ivermectin implant for livestock pest control.—pp. 223–236in Roseman, T. J. & Mansdorf, S. Z. (Eds.). Controlled release delivery systems for livestock pest control.—424 pp. New York, Marcel Dekker Inc.Google Scholar
Miller, J. A., Kunz, S. E., Oehler, D. D. & Miller, R. W. (1981). Larvicidal activity of Merck MK-933, an avermectin, against the horn fly, stable fly, face fly, and house fly.—J. econ. Ent. 74, 608–611.CrossRefGoogle Scholar
Moriena, R. A., Racioppi, O. & Lomardero, O. J. (1984). Utilizacion de la ivermectina y decemetrina como ’uricidas’ em bovinas de la Provincia de Corrientes.—Veterinaria, Argentina 1, 266–272.Google Scholar
Morse, J. G. & Brawner, O. L. (1986). Toxicity of pesticides to Scirtothrips citri (Thysanoptera: Thripidae) and implications to resistance management.—J. econ. Ent. 79, 565–570.CrossRefGoogle Scholar
Ostlind, D. A., Cifelli, S. & Lang, R. (1979). Insecticidal activity of the anti-parasitic avermectins.—Vet. Rec. 105, 168.CrossRefGoogle ScholarPubMed
Overman, A. J. & Price, J. F. (1984). Application of avermectin and cyromazine via drip irrigation and fenamiphos by soil incorporation for control of insect and nematode pests in chrysanthemums.—Proc. Fla St. hort. Soc. 97, 304–306.Google Scholar
Pampiglione, S., Majori, G., Petrangeli, G. & Romi, R. (1985). Avermectins, MK-933 and MK-936, for mosquito control.—Trans. R. Soc. trop. Med. Hyg. 79, 797–799.CrossRefGoogle ScholarPubMed
Parrella, M. P. (1983). Evaluations of selected insecticides for control of permethrin-resistant Liriomyza trifolii (Diptera: Agromyzidae) on chrysanthemum.—J. econ. Ent. 76, 1460–1464.CrossRefGoogle Scholar
Parrish, M. D. & Roberts, R. B. (1984). Toxicity of avermectin B1 to larval yellowjackets, Vespula maculifrons (Hymenoptera: Vespidae).—J. econ. Ent. 77, 769–772.CrossRefGoogle ScholarPubMed
Pienkowski, R. L. & Mehring, P. R. (1983). Influence of avermectin B1 and carbofuran on feeding by alfalfa weevil larvae (Coleoptera: Curculionidae).—J. econ. Ent. 76, 1167–1169.Google Scholar
Pfeiffer, D. G. (1985). Toxicity of avermectin B1 to San Jose scale (Homoptera: Diaspididae) crawlers, and effects on orchard mites by crawler sprays compared with full-season applications.—J. econ. Ent. 78, 1421–1424.CrossRefGoogle Scholar
Preston, J. M. (1982). The avermectins: new molecules for use in warble fly control.—pp. 17–20in Boulard, C. & Thornberry, H. (Eds.). Warble fly control in Europe.—156 pp. Rotterdam/Boston, A. A. Balkema.Google Scholar
Price, J. F. (1983). Field evaluations of new pesticides for control of leafminers, mites and aphids on flower crops.—Proc. Fla St. hort. Soc. 96, 287–291.Google Scholar
Putter, I., MacConnell, J. G., Preiser, F. A., Haidri, A. A., Ristich, S. S. & Dybas, R. A. (1981). Avermectins: novel insecticides, acaricides and nematicides from a soil microorganism.—Experientia 37, 963–964.CrossRefGoogle Scholar
Reed, D. K. & Reed, G. L. (1986). Activity of avermectin B1 against the striped cucumber beetle (Acalymma vittatum) (Coleoptera: Chrysomelidae).—J. econ. Ent. 79, 943–947.CrossRefGoogle Scholar
Reed, D. K., Tromley, N. J. & Reed, G. L. (1985). Activity of avermectin B1 against codling moth (Lepidoptera: Olethreutidae).—J. econ. Ent. 78, 1067–1071.CrossRefGoogle Scholar
Robertson, J. L., Richmond, C. E. & Preisler, H. K. (1985). Lethal and sublethal effects of avermectin B1 on the western spruce budworm (Lepidoptera: Tortricidae).—J. econ. Ent. 78, 1129–1132.CrossRefGoogle Scholar
Roncalli, R. A. (1984). The biology and control of Dermatobia hominis, the tropical warble-fly of Latin America.—Preventive vet. Med. 2, 569–578.CrossRefGoogle Scholar
Roush, R. T. & Wright, J. E. (1986). Abamectin: toxicity to house flies (Diptera: Muscidae) resistant to synthetic organic insecticides.—J. econ. Ent. 79, 562–564.CrossRefGoogle ScholarPubMed
Schmidt, C. D. (1983). Activity of avermectin against selected insects in aging manure.—Environ. Entomol. 12, 455–457.CrossRefGoogle Scholar
Schmidt, C. D. & Kunz, S. E. (1980). Testing immature laboratory-reared stable flies and horn flies for susceptibility to insecticides.—J. econ. Ent. 73, 702–703.CrossRefGoogle ScholarPubMed
Schröder, J., Swan, G. E., Soll, M. D. & Hotson, I. K. (1985). Efficacy of ivermectin against ectoparasites of cattle in South Africa.—J. South Afr. vet. Assoc. 56, 31–35.Google ScholarPubMed
Schuster, D. J. & Everett, P. H. (1983). Response of Liriomyza trifolii (Diptera: Agromyzidae) to insecticides on tomato.—J. econ. Ent. 76, 1170–1174.CrossRefGoogle Scholar
Spradbery, J. P., Tozer, R. S., Drewett, N. & Lindsey, M. J. (1985). The efficacy of ivermectin against larvae of the screw-worm fly (Chrysomya bezziana).—Aust. vet. J. 62, 311–314.CrossRefGoogle ScholarPubMed
Standfast, H. A., Muller, M. J. & Wilson, D. D. (1984). Mortality of Culicoides brevitarsis (Diptera: Ceratopogonidae) fed on cattle treated with ivermectin.—J. econ. Ent. 77, 419–421.CrossRefGoogle ScholarPubMed
Stewart, T. B., Marti, O. G. & Hale, O. M. (1981). Efficacy of ivermectin against 5 genera of swine nematodes and the hog louse Haematopinus suis.—Am. J. vet. Res. 42, 1425–1426.Google Scholar
Strong, L. (1986 a). Inhibition of pupariation and adult development in Calliphora vomitoria treated with ivermectin.—Entomologia exp. appl. 41, 157–164.CrossRefGoogle Scholar
Strong, L. (1986 b). Ivermectin prevents head eversion in the blowfly Calliphora vomitoria (L.).—Experientia 42, 1295–1296.CrossRefGoogle Scholar
Suckling, D. M., Kuijpers, L. & Rogers, D. J. (1985). Bioassay of some novel insecticides against lightbrown apple moth larvae.—Proc. N. Z. Weed & Pest Control Conf. no. 38, 45–49.Google Scholar
Tedders, W. L., Payne, J. A. & Taylor, J. L. (1984). Laboratory evaluation of avermectin B1 against the foliar aphids of pecan.—J. Georgia entomol. Soc. 19, 344–350.Google Scholar
Tichener, R. N. (1985). The control of lice on domestic livestock.—Vet. Parasitol. 18, 281–288.CrossRefGoogle Scholar
Trumble, J. T. (1985). Integrated pest management of Liriomyza trifolii: influence of avermectin, cyromazine and methomyl on leafminer ecology in celery.—Agric. Ecosystems & Environment 12, 181–188.CrossRefGoogle Scholar
van den Abbeele, J., D'Haeseleer, F. & Goossens, M. (1986). Efficacy of ivermectin on the reproductive biology of Glossina palpalis palpalis (Rob.-Desv.) (Glossinidae: Diptera).—Annls Soc. belge Méd. trop. 66, 167–172.Google Scholar
Wall, R. & Strong, L. (1987). Environmental consequences of treating cattle with the anti-parasitic drug ivermectin.—Nature (Lond.) 327, 418–421.CrossRefGoogle Scholar
Williams, D. F. (1985). Laboratory and field evaluation of avermectin against the imported fire ant.—Southwestern Entomologist Suppl. No. 7, 27–33.Google Scholar
Wolfenbarger, D. A., Johnson, A. W., Herzog, G. A. & Tappan, W. B. (1985). Activity of avermectin in the laboratory and the field against the boll weevil and Heliothis spp. on cotton and flue-cured tobacco.—Southwestern Entomologist Suppl. No. 7, 17–26.Google Scholar
Wright, C. G. & Dupree, H. E., Jr. (1985). Acephate and avermectins for German cockroach control.—J. ent. Sci. 20, 20–23.Google Scholar
Wright, D. E. (1986). Biological activity and mode of action of avermectins.—pp. 174–202in Ford, M. G., Lunt, G. G., Deay, R. C. & Usherwood, P. N. R. (Eds.). Neuropharmacology and pesticide action.—512 pp. Chichester, Ellis Horwood.Google Scholar
Wright, J. E. (1984). Biological activity of avermectin B1 against the boll weevil (Coleoptera: Curculionidae).—J. econ. Ent. 77, 1029–1032.CrossRefGoogle Scholar
Wright, J. E., Jenkins, J. N. & Villavaso, E. J. (1985). Evaluation of avermectin B1 (MK 936) against Heliothis spp. in the laboratory and in field plots and against the boll weevil in field plots.—Southwestern Entomologist Suppl. No. 7, 11–16.Google Scholar
Yazwinski, T. A., Greenway, T., Preston, B. L., Pote, L. M., Featherstone, H. & Williams, M. (1983). Antiparasitic activity of ivermectin in naturally parasitised sheep.—Am. J. vet. Res. 44, 2186–2187.Google Scholar
Yazwinski, T. A., Hamm, D., Greenway, T. & Tilley, W. (1982). Antiparasitic effectiveness of ivermectin in the horse.—Am. J. vet. Res. 43, 1092–1094.Google ScholarPubMed