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Duodenal infusion of conjugated linoleic acid mixture influences milk fat synthesis and milk CLA content in dairy cows

Published online by Cambridge University Press:  27 February 2018

J. Kraft ,
P. Lebzien ,
G. Flachowsky ,
P. Möckel  and
G. Jahreis
J. Kraft
Affiliation:
Institute of Nutrition, Friedrich Schiller University, Dornburger Str., 24, D–07743 Jena
P. Lebzien
Affiliation:
Institute of Animal Nutrition, Federal Agricultural Research Centre, Bundesallee 50, D–36112 Braunschweig, Germany
G. Flachowsky
Affiliation:
Institute of Animal Nutrition, Federal Agricultural Research Centre, Bundesallee 50, D–36112 Braunschweig, Germany
P. Möckel
Affiliation:
Institute of Nutrition, Friedrich Schiller University, Dornburger Str., 24, D–07743 Jena
G. Jahreis
Affiliation:
Institute of Nutrition, Friedrich Schiller University, Dornburger Str., 24, D–07743 Jena
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Abstract

Conjugated linoleic acids (CLA) are potent anticarcinogens secreted into the milk of ruminants. The present study was carried out to detect the post–ruminal effects of a duodenally infused commercial CLA product on milk–fat synthesis and fatty acid pattern in lactating cows. Four Holstein cows, fistulated with duodenal cannulae, were infused with 200 g of a CLA mixture daily into the duodenum over a period of 5 days (period II), while no application of CLA acted as controls in period I and III. In contrast to the marginal effect of the CLA application on milk yield, an obvious decrease of milk fat content of 40% was measured. The fat yield decreased during the infusion period to about half of the control period, whereas protein and lactose content in milk was not significantly influenced. The CLA percentage of milk fat increased sevenfold during infusion of the CLA supplement. The data demonstrate that duodenal infusion of CLA inhibits the milk fat synthesis, resulting in the decrease of milk fat content and fat yield. It can be concluded, that CLA supplements increase the CLA concentration in milk fat, which probably has to be rumen protected for oral administration.

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Posters
Information
BSAP Occasional Publication , Volume 25: Milk Composition , 2000 , pp. 143 - 147
Copyright
Copyright © British Society of Animal Science 2000

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References

Chin, S.F., Liu, W., Storkson, J.M., Ha, Y.L. and Pariza, M.W. 1992. Dietary sources of conjugated dienoic isomers of linoleic acid, a newly recognised class of anticarcinogens. Journal of Food Composition Analysis 5: 185–197.CrossRefGoogle Scholar
Drackley, J.K., Klusmeyer, T.H., Trusk, A.M. and Clark, J.H. 1992. Infusion of long-chain fatty acids varying in saturation and chain length into the abomasum of lactating dairy cows. Journal of Dairy Science 75: 1517–1526.Google Scholar
Forgerty, A.C., Ford, G.L. and Svoronos, D. 1988. Octadeca-9, 11-dienoic acid in food stuffs and in the lipids of human blood and breast milk. Nutrition Reports International 38: 937.Google Scholar
Jahreis, G., Fritsche, J. and Steinhart, H., 1997. Conjugated linoleic acid in milk fat: High variation depending on production system. Nutrition Research 17: 1479–1484.CrossRefGoogle Scholar
Jahreis, G., Fritsche, J. and Kraft, J. 1999. Species-dependent, seasonal, and dietary variation of conjugated linoleic acid in milk. In Conjugated linoleic acid: chemistry, biochemistry, nutrition and health, (ed Yurawecz, M.P. et al.) AOCS Press (in press).Google Scholar
Kelly, M.L. and Bauman, D.E. 1996. Conjugated linoleic acid: A potent anticarcinogen found in milk fat. Proceedings of the Cornell Nutrition Conference of Feed Manufacturers, Cornell University, Ithaca New York, 68–74.Google Scholar
Kepler, C.R. and Tove, S.B. 1967. Biohydrogenation of unsaturated fatty acids. III. Purification and properties of a linoleate ·12-cis, ·12-trans-isomerase from butyrivibrio fibrisolvens . Journal of Biological Chemistry 242: 5686–5692.CrossRefGoogle Scholar
Lee, K.N., Kritchevsky, D. and Pariza, M.W. 1994. Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis 108: 19–25.Google Scholar
Lin, H., Boylston, T.H., Chang, M.J., Luedecke, L.O. and Shultz, T.D. 1995. Survey of the conjugated linoleic acid contents of dairy products. Journal of Dairy Science 78: 2358–2365.Google Scholar
Loor, J.J. and Herbein, J.H. 1998. Exogenous conjugated linoleic acid isomers reduce bovine milk fat concentration and yield by inhibiting de novo fatty acid synthesis. Journal of Nutrition 128: 2411–2419.CrossRefGoogle ScholarPubMed
Pariza, M.W., Park, Y., Cook, M., Albright, K. and Liu, W. 1996. Conjugated linoleic acid (CLA) reduces body fat. FASEB Journal 10: 3227.Google Scholar
Parodi, P.W. 1994. Conjugated linoleic acid: An anticarcinogenic fatty acid present in milk fat. Australian Journal of Dairy Technology 49: 93–97.Google Scholar
Wagner, K., Aulrich, K., Lebzien, P. and Flachowsky, G. 1998. Research note: Effect of duodenal-infused unsaturated fatty acid on dairy milk composition. Archive of Animal Nutrition 51: 349–354.Google Scholar