Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-15T21:16:34.385Z Has data issue: false hasContentIssue false
  • English
  • Français

Zinc absorption in adult humans: the effect of protein sources added to liquid test meals

Published online by Cambridge University Press:  09 March 2007

Lena Davidsson ,
Annette Almgren ,
Brittmarie SandströM ,
Marc El-A Juillerat  and
Richard F Hurrell
Lena Davidsson
Affiliation:
Nestec Ltd, Nestl´Research Centre, PO Box 44, CH-1000 Lausanne 26, Switzerland
Annette Almgren
Affiliation:
Department of Clinical Nutrition, Gothenburg University, Annedalsklinikerna, S-41345 Göteborg, Sweden
Brittmarie SandströM
Affiliation:
Research Department of Human Nutrition, The Royal Veterinary and Agricultural University, Rolighedsvej 25, DK-1958 Fredriksberg, Denmark
Marc El-A Juillerat
Affiliation:
Nestec Ltd, Nestl´Research Centre, PO Box 44, CH-1000 Lausanne 26, Switzerland
Richard F Hurrell
Affiliation:
Nestec Ltd, Nestl´Research Centre, PO Box 44, CH-1000 Lausanne 26, Switzerland
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The influence of different protein sources on Zn absorption was evaluated in healthy adults by radioisotopic labelling of single meals, followed by whole-body retention measurements 14 d after intake. Semi-synthetic liquid diets were used for the evaluation of different animal-protein sources and dephytinized soyabean-protein isolate ( ··01 g phytic acid/kg). Zn absorption was measured in the same subjects from identical test meals containing no added protein. No statistically significant differences were found in the Zn absorption from test meals containing bovine whey, casein or egg albumen when compared with test meals without added protein. Bovine serum albumin (BSA) and soyabean-protein isolate (< ··01 g phytic acid/kg) significantly reduced the mean absorption of Zn from 45–49% (no added protein) to 38·0 (SD 10·9) (BSA, P < ··05) and 33·9 (SD 12·6)% (soyabean-protein isolate < ··01 g phytic acid/kg, P < ··01). These results demonstrate that Zn absorption is inhibited by certain protein sources, such as BSA and dephytinized soyabean-protein isolate, while other proteins have little or no effect.

Keywords

ZincProteinRadioisotope
Type
Zinc absorption
Information
British Journal of Nutrition , Volume 75 , Issue 4 , April 1996 , pp. 607 - 613
Copyright
Copyright © The Nutrition Society 1996

References

REFERENCES

Arvidsson, B., Cederblad, A., Björn-Rasmussen, E. &Sandström, B. (1978). A radionuclide technique for studies of zinc absorption in man. International Journal of Nuclear Medicine and Biology 5, 104–109.CrossRefGoogle ScholarPubMed
Cook, J. D. & Monsen, E. R. (1976). Food iron absorption in human subjects. 111. Comparison of the effect of animal proteins on nonheme iron absorption. American Journal of Clinical Nutrition 29, 859–867.CrossRefGoogle Scholar
Hurrell, R. F., Berrocal, R., Lynch, S. R., Dassenko, S. A. & Cook, J. D. (1990). The influence of bovine milk proteins on iron absorption in man. In Recent Knowledge on Iron and Folate Deficiencies in the World, pp. 265–273 [Hercberg, S., Galan, P. and Dupin, H., editors]. Paris: Colloque INSERM.Google Scholar
Hurrell, R.F., Juillerat, M.-A., Reddy, M. B., Lynch, S. R., Dassenko, S. A. & Cook, J. D. (1992). Soy protein, phytate and iron absorption in humans. American Journal of Clinical Nutrition 56, 573–578.CrossRefGoogle ScholarPubMed
Hurrell, R. F., Lynch, S. R., Trinidad, T. P., Dassenko, S. A. & Cook, J. D. (1988). Iron absorption in humans: bovine serum albumin compared with beef muscle and egg white. American Journal of Clinical Nutrition 47, 102–107.CrossRefGoogle ScholarPubMed
Hurrell, R. F., Lynch, S. R., Trinidad, T. P., Dassenko, S. A. & Cook, J. D. (1989). Iron absorption in humans as influenced by bovine milk proteins. American Journal of Clinical Nutrition 49, 546–552.CrossRefGoogle ScholarPubMed
International Commission on Radiological Protection (1987). ICRP publication 53. Radiation dose to patients from radiopharmaceuticals. Annals of the ZCRP 18, 1–4.Google Scholar
Kivistö, B., Cederblad, A., Davidsson, L., Sandberg, A. -S. & Sandström, B. (1989). Effect of meal composition and phytate content on zinc absorption in humans from an extruded bran product. Journal of Cereal Science 10, 189–197.CrossRefGoogle Scholar
Lönnerdal, B., Cederblad, A., Davidsson, L. & Sandström, B. (1984). The effect of individual components of soy formula and cow's milk formula on zinc bioavailability. American Journal of Clinical Nutrition 40, 1064–1070.CrossRefGoogle ScholarPubMed
Lynch, S. R., Dassenko, S. A., Cook, J. D., Juillerat, M.-A. & Hurrell, R. F. (1995). Inhibitory effect of a soybean-protein related moiety on iron absorption in humans. American Journal of Clinical Nutrition 60, 567–572.CrossRefGoogle Scholar
Makover, R. U. (1970). Extraction and determination of phytic acid in beans. Cereal Chemistry 47, 288–296.Google Scholar
Nävert, B., Sandström, B. & Cederblad, A. (1985). Reduction of the phytate content of bran by leavening in bread and its effect on absorption of zinc in man. British Journal of Nutrition 53, 47–53.Google ScholarPubMed
Sandström, B., Arvidsson, B., Cederblad, A. & Björn-Rasmnssen, E. (1980). Zinc absorption from composite meals. I. The significance of wheat extraction rate, zinc, calcium, and protein content in meals based on bread. American Journal of Clinical Nutrition 33, 739–745.CrossRefGoogle ScholarPubMed
Sandström, B. & Cederblad, A. (1980). Zinc absorption from composite meals. II. Influence of the main protein source. American Journal of Clinical Nutrition 33, 1778–1783.CrossRefGoogle ScholarPubMed
Sandström, B., Cederblad, A. & Lönnerdal, B. (1983). Zinc absorption from human milk, cow's milk and infant formulas. American Journal of Diseases in Children 137, 726–729.Google ScholarPubMed
Sandström, B., Davidsson, L., Cederblad, A. & Lönnerdal, B. (1985). Oral iron, dietary ligands and zinc absorption. Journal of Nutrition 115,411–414.CrossRefGoogle ScholarPubMed