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WHO sponsored collaborative studies on nutritional anaemia in India

Published online by Cambridge University Press:  09 March 2007

S. K. Sood ,
K. Ramachandran ,
Kamla Rani ,
V. Ramalingaswami ,
V. I. Mathan ,
J. Ponniah  and
S. J. Baker
S. K. Sood
Affiliation:
Department of Pathology and Biostatistics, All-India Institute of Medical Sciences, New Delhi and Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India
K. Ramachandran
Affiliation:
Department of Pathology and Biostatistics, All-India Institute of Medical Sciences, New Delhi and Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India
Kamla Rani
Affiliation:
Department of Pathology and Biostatistics, All-India Institute of Medical Sciences, New Delhi and Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India
V. Ramalingaswami
Affiliation:
Department of Pathology and Biostatistics, All-India Institute of Medical Sciences, New Delhi and Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India
V. I. Mathan
Affiliation:
Department of Pathology and Biostatistics, All-India Institute of Medical Sciences, New Delhi and Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India
J. Ponniah
Affiliation:
Department of Pathology and Biostatistics, All-India Institute of Medical Sciences, New Delhi and Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India
S. J. Baker
Affiliation:
Department of Pathology and Biostatistics, All-India Institute of Medical Sciences, New Delhi and Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India
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Abstract

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1. The relative efficacy of oral and parenteral iron administration in the prophylaxis and treatment of Fe-deficiency anaemia of pregnancy has been studied.

2. Intravenous administration of Fe by total dose infusion of Fe dextran was not superior to oral Fe 120 mg/d, 6 d/week for 10–12 weeks.

3. Intramuscular Fe dextran, 100 mg twice per week for 10–12 weeks, produced a significantly greater rise in mean haemoglobin concentration than oral Fe therapy.

4. The superiority of intramuscular Fe as compared with intravenous Fe is probably related to the different handling of the Fe dextran by the reticulo-endothelial system.

5. In spite of the better response to intramuscular Fe dextran, it is not recommended for public health practice because of the risks associated with its use and the much higher cost of the preparation and its delivery.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 42 , Issue 3 , November 1979 , pp. 399 - 406
Copyright
Copyright © The Nutrition Society 1979

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