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Urinary excretion of magnesium and calcium as an index of absorption is not affected by lactose intake in healthy adults

Published online by Cambridge University Press:  09 March 2007

Elizabeth J. Brink ,
Emerentia C. H. van Beresteijn ,
Pieter R. Dekker  and
Anton C. Beynen
Elizabeth J. Brink
Affiliation:
Department of Nutrition, Netherlands Institute for Dairy Research, PO Box 20, 6710 BA Ede, The Netherlands
Emerentia C. H. van Beresteijn
Affiliation:
Department of Nutrition, Netherlands Institute for Dairy Research, PO Box 20, 6710 BA Ede, The Netherlands
Pieter R. Dekker
Affiliation:
Department of Nutrition, Netherlands Institute for Dairy Research, PO Box 20, 6710 BA Ede, The Netherlands
Anton C. Beynen
Affiliation:
Department of Laboratory Animal Science, State University, Utrecht, The Netherlands and Department of Human Nutrition, Agricultural University, Wageningen, The Netherlands
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Abstract

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The effect of lactose on the urinary excretion of Mg and Ca, as an index of absorption, was studied in a double-blind, crossover study during three 1-week periods. Twenty-four healthy, lactose-tolerant, adult volunteers maintained their habitual diets with the exception that all lactose-containing dairy products in the diet were replaced by 600 g/d of three specially prepared dairy products. These products were based on either lactose-enriched cow's milk or lactose-enriched, lactase (EC 3.2.1.23)-treated cow's milk, with or without added Mg, and were given in turn during 1 week. Lactose intake was increased by 127 mmol/d (46 g/d) while taking the lactose-enriched products. While taking the Mg-enriched products, Mg intake was increased by 2.8 mmol/d (69 mg/d) which was equivalent to 17% of the habitual Mg intake. Apart from the lactose and Mg intake, nutrient intake was comparable during the three dietary periods. Urinary excretions of Mg and Ca were used as indicators for their absorption. Mg supplementation significantly increased urinary Mg excretion by 0.97 mmol/d (equivalent to an increase of 18%, P < 0.001), indicating that urinary Mg excretion is a valid indicator for intestinal Mg absorption. Hydrolysis of lactose did not affect urinary excretion of Mg and Ca, which implies that lactose intake does not affect the absorption of Mg and Ca in healthy adults.

Keywords

LactoseMagnesiumCalciumHumans
Type
Mineral Metabolism
Information
British Journal of Nutrition , Volume 69 , Issue 3 , May 1993 , pp. 863 - 870
Copyright
Copyright © The Nutrition Society 1993

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