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Time-course of the change in blood pressure level in magnesium-deficient Wistar rats

Published online by Cambridge University Press:  09 March 2007

Pascal Laurant ,
Michel Dalle ,
Alain Berthelot  and
Yves Rayssiguier
Pascal Laurant
Affiliation:
Laboratoire Physiologie, Pharmacologie et Nutrition Préventive Expérimentale, UFR Médecine et Pharmacie, Place St-Jacques, 25030, Besançon Cedex, France
Michel Dalle
Affiliation:
Laboratoire de Physiologie Animale, Université Blaise Pascal, 63000, Clermont-Ferrand, France
Alain Berthelot
Affiliation:
Laboratoire Physiologie, Pharmacologie et Nutrition Préventive Expérimentale, UFR Médecine et Pharmacie, Place St-Jacques, 25030, Besançon Cedex, France
Yves Rayssiguier*
Affiliation:
CRNH d’Auvergne, INRA, Unité Maladies Métaboliques et Micronutriments, Theix, 63122, Saint Genès Champanelle, France
*
*Corresponding author: Dr Yves Rayssiguier, fax +33 4 73 62 46 38, email [email protected]
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Abstract

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To investigate the relationships between maternal, umbilical cord and piglet fatty acid status, multiparous sows (six per diet) were fed on diets containing supplements (30 g/kg) of either soyabean oil or tuna oil for the last 21 d of pregnancy. The proportions of most fatty acids differed between diets: in particular, the tuna-oil-containing diet supplied more 22:6n-3 and less 18:2n-6 fatty acids than the soyabean-oil-containing diet. Maternal plasma fatty acid concentrations (mg/l) were greater than those in umbilical plasma and 20:4n-6 and 22:6n-3 fatty acids were present in higher proportions (g/100 g fatty acids) in umbilical than maternal plasma. Feeding tuna oil increased the proportionate amounts (g/100 g fatty acids) of total n-3 fatty acids (particularly 22:6n-3) in umbilical cord, plasma and piglet tissues compared with feeding soyabean oil: in contrast, the proportion of 20:4n-6 was decreased by feeding tuna oil. Changes in piglet fatty acid proportions as a result of oil feeding were not influenced by piglet weight. While proportions of the long-chain n-3 and n-6 polyunsaturated fatty acids in piglet liver, spleen and reproductive tract (ovaries plus uterus of the female, testes of the male) correlated well with those of umbilical plasma, those in brain and retina were poorly correlated. Therefore umbilical plasma cannot be used to predict the fatty acid status of piglet brain.

Keywords

PregnancyDietary fatty acidsTissue fatty acidsPig
Type
Research Article
Information
British Journal of Nutrition , Volume 82 , Issue 3 , September 1999 , pp. 243 - 251
Copyright
Copyright © The Nutrition Society 1999

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