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A study of the relationship between Hess tests and leucocyte ascorbic acid in a clinical trial

Published online by Cambridge University Press:  09 March 2007

T. P. Eddy
T. P. Eddy
Affiliation:
Department of Human Nutrition, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT
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Abstract

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1. The results of a previously reported controlled trial of vitamin supplementation of elderly hospital patients, in which capillary resistance was measured by the Hess test, were examined and analysed statistically.

2. Capillary resistance was reduced during successive 3-monthly tests over a period of 12 months and the reduction was related to leucocyte ascorbic acid concentration.

3. It is postulated that the rate of recovery from capillary trauma inflicted by the test was dependent upon the function of ascorbic acid in the hydroxylation of proline to hydroxyproline during collagen synthesis.

Type
Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 27 , Issue 3 , May 1972 , pp. 537 - 542
Copyright
Copyright © The Nutrition Society 1972

References

Baker, E. M., Hodges, R. E., Hood, J., Sauberlich, H. E., March, S. C. & Canham, J. E. (1971). Am. J. clin. 24, 444.CrossRefGoogle Scholar
Bartley, W., Krebs, H. A. & O'Brien, J. R. P. (1953). Spec. Rep. Ser. med. Res. Coun. no. 280.Google Scholar
Brocklehurst, J. C., Griffiths, L. L., Taylor, G. F., Marks, J., Scott, D. L. & Blackley, J. (1968). Geront. clin. 10, 309.CrossRefGoogle Scholar
Göthlin, G. F. (1931). Skand. Arch. Physiol. 61, 225.CrossRefGoogle Scholar
Göthlin, G. F. (1933). J. Lab. din. 18, 484.Google Scholar
Griffiths, L. L. (1968). In Vitamins in the Elderlyp.34 [Exton-Smith, A. N. and Scott, D. L., editors]. Bristol: John Wright.CrossRefGoogle Scholar
Griffiths, L. L., Brocklehurst, J. C., Scott, D. L.,Marks, J. & Blackley, J. (1967). Geront. clin. 9, 1.CrossRefGoogle Scholar
Hess, A. F. (1913). Proc. Sac. exp. Bid. Men. 11, 130.CrossRefGoogle Scholar
Hodges, R. E., Hood, J., Canham, J. E., Sauberlich, H. E. & Baker, E. M. (1971). Am. J. clin. 24, 432.CrossRefGoogle Scholar
Krasner, N. & Dymock, I. W. (1970). Int. J. Vitam. Res. 40, 427.Google Scholar
Munro, H. N., Lazarus, S. & Bell, G. H. (1947–1948). Nutr. Abstr. Rev. 17, 291.Google Scholar
Priest, R. E. (1970). Nature, Land. 225, 744.CrossRefGoogle Scholar
TayIor, G. F. (1968). In Vitamins in the Elderly p.51 [Exton-Smith, A. N. E and Scott, D. L., editors]. Bristol: John Wright.Google Scholar
Udenfriend, S. (1966). Science, N.Y. 152, 1335.CrossRefGoogle Scholar
Windsor, A. C. W. & Williams, C. B. (1970). Br. med. J. i, 732.CrossRefGoogle Scholar