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Studies on total body potassium in malnourished infants Factors affecting potassium repletion

Published online by Cambridge University Press:  09 March 2007

G. A. O. Alleyne
G. A. O. Alleyne
Affiliation:
Medical Research Council, Tropical Metabolism Research Unit, University of the West Indies, Jamaica
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Abstract

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1. Serial measurements of total body potassium were made in children while they were malnourished and as they recovered. Initially, there was a low total body potassium which rose slowly and reached the normal levels of 45 m-equiv./kg at 3–4 weeks after admission to hospital.

2. The early stages of recovery were divided into three phases. In the first 5 days of treatment, retention of potassium served to correct a true potassium deficiency and the amount of potassium retained during this phase was related to the initial level of total body potassium. There was no relationship between serum potassium and total body potassium. There was indirect evidence that antecedent diarrhoea was an important factor in the production of potassium depletion.

3. In the next phase—the lag phase—potassium was retained in relation to deposition of new body tissue.

4. In the phase of rapid growth, potassium was also retained in the amount appropriate for deposition of new tissue.

5. After the repair of the acute potassium depletion, potassium retention was always correlated with the protein intake.

Type
Research Article
Information
British Journal of Nutrition , Volume 24 , Issue 1 , March 1970 , pp. 205 - 212
Copyright
Copyright © The Nutrition Society 1970

References

Alleyne, G. A. O. (1965). Renal and cardiac function in severely malnourished Jamaican infants. MD Thesis, University of London.Google Scholar
Alleyne, G. A. O. (1968). Clin. Sci. 34, 199.Google Scholar
Alleyne, G. A. O., Millward, D. J. & Scullard, G. H. (1969). J. Pediat. (In the Press.)Google Scholar
Ashworth, A., Bell, R., James, W. P. T. & Waterlow, J. C. (1968). Lancet ii, 600.CrossRefGoogle Scholar
Frenk, S., Metcoff, J., Gómez, F., Ramos-Galván, R., Cravioto, J. & Antonowicz, I. (1957). Pediatrics, Springfield 20, 105.CrossRefGoogle Scholar
Carrow, J. S. (1965 a). Lancet ii, 455.Google Scholar
Garrow, J. S. (1965 b). W. Indian med. J. 14, 73.Google Scholar
Garrow, J. S., Fletcher, K. & IIalliday, D. (1965). J. clin. Invest. 44, 417.CrossRefGoogle Scholar
Garrow, J. S., Smith, R. & Ward, E. E. (1968). Electrolyte Metabolism in Severe Infantile Malnutrition. London: Pergamon Press.Google Scholar
Hansen, J. D. L. (1956). S. Afr. J. Lab. clin. Med. 2, 206.Google Scholar
Metcoff, J., Frenk, S., Antonowicz, I., Gordillo, G. & Lopez, E. (1960). Pediatrics, Springfield 26, 960.CrossRefGoogle Scholar
Nelson, W. E. (1959). Textbook of Pediatrics, 7th ed. Philadelphia and London: W. B. Saunders Co.Google Scholar
Nichols, B. L., Alleyne, G. A. O., Barnes, D. J. & Hazlewood, C. F. (1969). J. Pediat. 74, 49.CrossRefGoogle Scholar
Picou, D., Alleyne, G. A. O. & Seakins, A. (1965). Clin. Sci. 29, 517.Google Scholar
Pretorius, P. J. & Wehmeyer, A. S. (1964). S. Afr. J. Lab. clin. Med. 10, 52.Google Scholar
Scribncr, B. H. & Burnell, J. M. (1956). Metabolism 5, 468.Google Scholar
Smith, R. & Waterlow, J. C. (1960). Lancet i, 147.CrossRefGoogle Scholar
Standard, K. I., Wills, V. G. & Waterlow, J. C. (1959). Am. J. clin. Nutr. 7, 271.CrossRefGoogle Scholar
Vis, H., Dubois, H., Vanderborght, H. & de Mayer, E. (1965). Revue fr. Etud. clin. biol. 10, 729.Google Scholar
Waterlow, J. C., Cravioto, J. & Stephen, J. M. L. (1960). Adu. Protein Chem. 15, 131.CrossRefGoogle Scholar
Waterlow, J. C. & Mendes, C. B. (1957). Nature, Lond. 180, 1361.CrossRefGoogle Scholar
Waterlow, J. C. & Wills, V. G. (1960). Br. J. Nutr. 14, 183.CrossRefGoogle Scholar