Hostname: page-component-cd9895bd7-jkksz Total loading time: 0 Render date: 2024-12-25T03:07:22.662Z Has data issue: false hasContentIssue false
  • English
  • Français

Some effects of selenium deficiency on glutathione peroxidase (EC 1.11.1.9) activity and tissue pathology in rainbow trout (Salmo gairdneri)

Published online by Cambridge University Press:  09 March 2007

J. G. Bell ,
B. J. S. Pirie ,
J. W. Adron  and
C. B. Cowey
J. G. Bell
Affiliation:
Institute of Marine Biochemistry, St Fittick's Road, Aberdeen AB1 3RA
B. J. S. Pirie
Affiliation:
Institute of Marine Biochemistry, St Fittick's Road, Aberdeen AB1 3RA
J. W. Adron
Affiliation:
Institute of Marine Biochemistry, St Fittick's Road, Aberdeen AB1 3RA
C. B. Cowey
Affiliation:
Institute of Marine Biochemistry, St Fittick's Road, Aberdeen AB1 3RA
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Two duplicate groups of rainbow trout (Sulmo gairdneri; mean weight 27 g) were given diets of differing selenium content (deficient 0, 025 mg Se/kg; supplemented 1.022 mg Se/kg) for 30 weeks.

2. There were no significant differences between treatments in weight gain but packed cell volume, liver vitamin E and liver and plasma Se concentrations were all significantly lower in the Se-deficient trout.

3. Ataxia occurred in about 10% of the Se-deficient trout and histopathologies were evident in nerve cord (damage to axon sheath) and liver (loss of integrity in endoplasmic reticulum and mitochondria with appearance of increased vesiculation).

4. Glutathione peroxidase (EC 1.11.1.9) activity was significantly reduced in liver and plasma of Se-deficient fish but there was no indication, from differential assay, of any non-Se-dependent glutathione peroxidase activity. Glutathione transferase (EC 2.5. I.18) activity was significantly increased in Se-deficient trout.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 55 , Issue 2 , March 1986 , pp. 305 - 311
Copyright
Copyright © The Nutrition Society 1986

References

REFERENCES

Bell, J. G., Cowey, C. B., Adron, J. W. & Shanks, A. M. (1985). British Journal of Nutrition 53, 149–157.CrossRefGoogle Scholar
Bell, J. G., Cowey, C. B. & Youngson, A. (1984). Biochimica et Biophysica Acta 795, 91–99.CrossRefGoogle Scholar
Cadenas, E., Ginsberg, M., Rabe, U. & Sies, H. (1984). Biochemical Journal 223, 755–759.CrossRefGoogle Scholar
Cowey, C. B., Adron, J. W., Walton, M. J., Murray, J., Youngson, A. & Knox, D. (1981). Journal of Nutrition 111, 1556–1567.CrossRefGoogle Scholar
Gatlin, D. M. & Wilson, R. P. (1984). Journal of Nutrition 114, 627–633.CrossRefGoogle Scholar
Habig, W. H., Pabst, M. J. & Jackoby, W. B. (1974). Journal of Biological Chemistry 249, 7130–7139.CrossRefGoogle Scholar
Hasunuma, R., Ogawa, T. & Kawanishi, Y. (1982). Analytical Biochemistry 126, 242–245.CrossRefGoogle Scholar
Hilton, J. W., Hodson, P. V. & Slinger, S. J. (1980). Journal of Nutrition 110. 2527–2535.CrossRefGoogle Scholar
Hung, S. S. O., Cho, C. Y. & Slinger, S. J. (1980). Journal of the Association of Of Journal Analytical Chemists 63, 889–893.Google Scholar
Lawrence, R. A., Parkhill, L. K. & Burk, R. F. (1978). Journal of Nutrition, 108, 981–987.CrossRefGoogle Scholar
Lowry, O.H., Roseburgh, N. J., Farr, A. L. & Randall, R. J. (1951). Journal of Biological Chemistry 193, 265–275.CrossRefGoogle Scholar
McMurray, C. H., Blanchflower, W. J. & Rice, D. A. (1980). Journal of the Associalion of Official Anatylical Chemists 63, 1258–1261.Google Scholar
Oh, S.-H., Sunde, R. A, Pope, A. L. & Hoekstra, W. G. (1976). Journal of Animal Science 42, 977–983.CrossRefGoogle Scholar
Pierce, S. & Tappel, A. L. (1978). Biochimica et Biophysica Acta 611, 87–98.Google Scholar
Schwarz, K. & Folz, C. M. (1957). Journal of the American Chemical Society 79, 3293–3298.Google Scholar
Siddons, R. C. & Mills, C. F. (1981). British Journal of Nutrition 46, 345–355.CrossRefGoogle Scholar
Walton, M. J., Cowey, C. B. & Adron, J. W. (1982). Journal of Nutrition 112, 1525–1535.CrossRefGoogle Scholar
Xu, G.-L. & Diplock, A. T. (1983). British Journal of Nutrition 50, 437–444.CrossRefGoogle Scholar