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School-milk intervention trial enhances growth and bone mineral accretion in Chinese girls aged 10–12 years in Beijing

Published online by Cambridge University Press:  09 March 2007

Xueqin DU ,
Kun Zhu ,
Angelika Trube ,
Qian Zhang ,
Guansheng Ma ,
Xiaoqi Hu ,
David R. Fraser  and
Heather Greenfield
Xueqin DU*
Affiliation:
Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia
Kun Zhu
Affiliation:
Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia
Angelika Trube
Affiliation:
Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia
Qian Zhang
Affiliation:
Institute for Nutrition and Food Safety, Chinese Centre for Disease Control and Prevention, Beijing, China
Guansheng Ma
Affiliation:
Institute for Nutrition and Food Safety, Chinese Centre for Disease Control and Prevention, Beijing, China
Xiaoqi Hu
Affiliation:
Institute for Nutrition and Food Safety, Chinese Centre for Disease Control and Prevention, Beijing, China
David R. Fraser
Affiliation:
Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia
Heather Greenfield
Affiliation:
Faculty of Veterinary Science, The University of Sydney, NSW 2006, Australia
*
*Corresponding author: fax +61 2 9351 2114, Email [email protected]
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Abstract

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A 2-year milk intervention trial was carried out with 757 girls, aged 10 years, from nine primary schools in Beijing (April 1999 – March 2001). Schools were randomised into three groups: group 1, 238 girls consumed a carton of 330 ml milk fortified with Ca on school days over the study period; group 2, 260 girls received the same quantity of milk additionally fortified with 5 or 8 μg cholecalciferol; group 3, 259 control girls. Anthropometric and bone mineralisation measurements, as well as dietary, health and physical-activity data, were collected at baseline and after 12 and 24 months of the trial. Over the 2-year period the consumption of this milk, with or without added cholecalciferol, led to significant increases in the changes in height (≥0·6%), sitting height (≥0·8%), body weight (≥2·9%), and (size-adjusted) total-body bone mineral content (≥1·2%) and bone mineral density (≥3·2%). Those subjects receiving additional cholecalciferol compared with those receiving the milk without added 25-hydoxycholecalciferol had significantly greater increases in the change in (size-adjusted) total-body bone mineral content (2·4 v. 1·2%) and bone mineral density (5·5 v. 3·2%). The milk fortified with cholecalciferol significantly improved vitamin D status at the end of the trial compared with the milk alone or control groups. It is concluded that an increase in milk consumption, e.g. by means of school milk programmes, would improve bone growth during adolescence, particularly when Ca intake and vitamin D status are low.

Keywords

Milk supplementAdolescent bone growthVitamin DCa
Type
Research Article
Information
British Journal of Nutrition , Volume 92 , Issue 1 , July 2004 , pp. 159 - 168
Copyright
Copyright © The Nutrition Society 2004

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