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Role of vitamin E in the aetiology of phrynoderma (follicular hyperkeratosis) and its interrelationship with B-complex vitamins

Published online by Cambridge University Press:  09 March 2007

H. A. Nadiger
H. A. Nadiger
Affiliation:
National Institute of Nutrition, Indian Council of Medical Research, Hyderabad – 500 007, India
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Abstract

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1. A study was undertaken to investigate the role of vitamin E in the aetiology of phrynoderma (follicular hyperkeratosis). Fifty-six children with the disease and twenty-one normal children were investigated for this purpose.

2. Plasma vitamin E levels (mean±SE; mg/l) were found to be low in phrynoderma (3.7±0.19) in contrast with normal children (6.6±0.40) and therapy with a combination of vitamin E and B-complex brought about complete cure.

3. The increase in plasma vitamin E levels after the administration of vitamin E at a dose of 100 mg three times daily for 4 weeks was higher than that obtained when vitamin E at the same dose was administered together with vitamin B-complex for 4 weeks, suggesting an interaction between the two vitamins. Further studies are necessary to find out the exact nature of this interrelationship.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 44 , Issue 3 , November 1980 , pp. 211 - 214
Copyright
Copyright © The Nutrition Society 1980

References

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