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Retinol transport proteins and concentrations in human amniotic fluid, placenta, and fetal and maternal sera

Published online by Cambridge University Press:  24 July 2007

D. Sklan ,
I. Shalit ,
N. Lasebnik ,
Z. Spirer  and
Y. Weisman
D. Sklan
Affiliation:
Faculty of Agriculture, Israel
I. Shalit
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
N. Lasebnik
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
Z. Spirer
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
Y. Weisman
Affiliation:
Departments of Pediatrics, and Obstetrics and Gynaecology, Tel Aviv Medical Center, Tel Aviv University, Sackler Medical School, Tel Aviv, Israel
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Abstract

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1. The proteins binding retinol, and retinol concentrations, were determined in amniotic fluid, placental cytosol and in the fetal and maternal circulation.

2. In non-pregnant women, plasma retinol was almost exclusively found in a transthyretin-retinol-binding-protein complex whereas, in pregnant women, retinol-binding-protein-bound retinol was observed not complexed to transthyretin. This latter fraction increased in concentration with fetal age. These two fractions were the major retinol-protein complexes in amniotic fluid and their relative amounts changed with progress of gestation.

3. In fetal blood both of these fractions were again found, with higher proportions of retinol-binding- protein-bound retinol in the umbilical artery than in the umbilical vein.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 54 , Issue 3 , November 1985 , pp. 577 - 583
Copyright
Copyright © The Nutrition Society 1985

References

Bates, C. J. (1983). Proceedings of the Nutrition Society 42, 65–79.CrossRefGoogle Scholar
Bradford, M. M. (1976). Analytical Biochemistry 72, 248–252.Google Scholar
Burnett, D. & Bradwell, A. R. (1980). Biology of the Neoate 37, 302–307.CrossRefGoogle Scholar
Donoghue, S., Richardson, D. W., Sklan, D. & Kronfeld, D. S. (1982). Journal of Nutrition 112, 2197–2203.Google Scholar
Hemmings, C. & Hemmings, W. A. (1979). In Protein Transmission through living membranes, pp. 269–276 [Hemmings, W. A., editor]. Amsterdam: Elsevier.Google Scholar
Ismadi, S. D. & Olson, J. A. (1975). American Journal of Clinical Nutrition 28, 967–972.CrossRefGoogle Scholar
Ismadi, S. D. & Olson, J. A. (1982). International Journal of Vitamin and Nutrition Research 52, 111–118.Google Scholar
Mallia, A. K., Smith, J. E. & Goodman, D. S. (1975). Journal of Lipid Research 16, 180–188.CrossRefGoogle Scholar
Moore, T. (1971). International Journal of Vitamin and Nutrition Research 41, 301–306.Google Scholar
Nanda, R., May, D. L. & Lite, S. (1977). Oral Biology 22, 613–618.Google Scholar
Ong, D. (1984). Journal of Biological Chemistry 259, 1476–1482.Google Scholar
Parkinson, C. E., Tan, J. C. Y. & Gal, I. (1982). British Journal of Obstetrics and Gynaecology 89, 935–939.Google Scholar
Sklan, D., Blaner, W. S., Adachi, N., Smith, J. E. & Goodman, D. S. (1982). Archives of Biochemistry and Biophysics 214, 35–44.CrossRefGoogle Scholar
Sklan, D. & Donoghue, S. (1982). Biochimica et Biophysica Acta 711, 532–538.Google Scholar
Sklan, D. & Halevy, O. (1984). British Journal of Nutrition 52, 107–114.Google Scholar
Smith, J. E. & Goodman, D. S. (1979). Federation Proceedings 38, 60–65.Google Scholar
Takahashi, Y. I., Smith, J. E. & Goodman, D. S. (1977). American Journal of Physiology 223, E263–E272.Google Scholar
Vahlquist, A., Rask, L., Peterson, P. A. & Berg, T. (1975). Scandinavian Journal of Laboratory and Clinical Investigation 35, 569–575.CrossRefGoogle Scholar
Wallingford, J. C., Milunsky, A. & Underwood, B. A. (1983). American Journal of Clinical Nutrition 38, 377–381.Google Scholar
Wild, A. E. (1974). Symposium of the Society of Experimental Biology 28, 521–546.Google Scholar
Wilson, J. G., Roth, C. B. & Warkany, J. (1953). American Journal of Anatomy 92, 189–217.Google Scholar