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Relationship between the ratio of increase in lean tissue to body weight gain and energy required to gain body weight in growing rats

Published online by Cambridge University Press:  19 December 2024

Kiyora Obikawa ,
Mizuki Kitaguchi ,
Emi Kondo Open the ORCID record for Emi Kondo [Opens in a new window]  and
Koji Okamura
Kiyora Obikawa
Affiliation:
Graduate School of Sport and Exercise Sciences, Osaka University of Health and Sport Sciences, 1-1 Asashirodai, Kumatori-cho, Sennan-gun, Osaka 590-0496, Japan
Mizuki Kitaguchi
Affiliation:
Graduate School of Sport and Exercise Sciences, Osaka University of Health and Sport Sciences, 1-1 Asashirodai, Kumatori-cho, Sennan-gun, Osaka 590-0496, Japan
Emi Kondo
Affiliation:
Graduate School of Sport and Exercise Sciences, Osaka University of Health and Sport Sciences, 1-1 Asashirodai, Kumatori-cho, Sennan-gun, Osaka 590-0496, Japan
Koji Okamura*
Affiliation:
Graduate School of Sport and Exercise Sciences, Osaka University of Health and Sport Sciences, 1-1 Asashirodai, Kumatori-cho, Sennan-gun, Osaka 590-0496, Japan
*
Corresponding author: Koji Okamura; Email: [email protected]
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Abstract

Although the energy stored in the lean tissue (LT) and adipose tissue (AT) is well known, the energy required to synthesise these tissues is obscure. Theoretically, the energy at the point at which ΔLT/Δ body weight (BW) reaches 100 % on a regression line, which indicates the relationship between ΔLT/ΔBW and the energy required for BW gain, is considered to be the energy expended to synthesise LT. Therefore, we investigated this relationship in rats. Rats were fed diets with different ratios of protein, fat and carbohydrates because their ΔLT/ΔBW values were expected to be different. Six-week-old male Sprague-Dawley rats had ad libitum access to normal (N, n 6), high-fat (HF, n 7) or high-protein (HP, n 8) diets for 4 weeks. The ΔLT/ΔBW was 0·77 in the N, 0·70 in the HF and 0·87 in the HP groups, respectively. The average energy required to gain BW was 8·8 kJ/g in the N group, 7·0 kJ/g in the HF group and 11·3 kJ/g in the HP group. We observed a positive correlation between ΔLT/ΔBW and energy required for BW gain. The regression line demonstrated that the energy expended to synthesise LT was 13·9 kJ/g and AT was −7·9 kJ/g. Therefore, combined with the energy stored in LT, the energy required to accumulate LT is approximately 19 kJ/g, whereas the energy to accumulate AT could not be elucidated.

Keywords

Energy intakeEnergy to storeMaintenance energyFat-free massFat mass
Type
Research Article
Information
British Journal of Nutrition , Volume 133 , Issue 2 , 28 January 2025 , pp. 202 - 210
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Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of The Nutrition Society

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