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Obesity, insulin resistance and diabetes — a worldwide epidemic

Published online by Cambridge University Press:  09 March 2007

Jacob C. Seidell
Jacob C. Seidell*
Affiliation:
Department of Chronic Diseases Epidemiology National Institute of Public Health and the Environment, PO Box 1, 3720 BA Bilthoven, and Institute for Research in Extramural Medicine, Free University Amsterdam, The Netherlands
*
*Corresponding author: J. C. Seidell, fax +31 30 274 4407, email [email protected]
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Abstract

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Obesity is now commonly defined in adults as a BMI > 30 kg/m2. The prevalence of obesity in established market economies (Europe, USA, Canada, Australia, etc.) varies greatly, but a weighed estimate suggests an average prevalence in the order of 15–20 %. The prevalence in these countries generally shows increasing trends over time. Obesity is also relatively common in Latin America, but much less so in sub-Saharan Africa and Asia where the majority of the world population lives. Nevertheless obesity rates are increasing there as well and, more importantly, rates of diabetes are increasing even more quickly, particularly in Asian countries. The risks of type 2 diabetes mellitus in these countries tend to increase sharply at levels of BMI generally classified as acceptable in European and North American white people. There have been suggestions to adopt specific classifications of obesity in Asians (e.g. BMI 23 for overweight and 25 or 27 kg/m2 for obesity) and this will greatly affect the prevalence estimates of obesity worldwide (currently at about 250 million people). Particularly for health promotion purposes BMI may be replaced by a classification based on waist circumference, but also specific classifications for different ethnic groups may be necessary. The number of diabetics has been projected to increase from 135 million in 1995 to 300 million in 2025. Much of this increase will be seen in Asia. In summary, both obesity and type 2 diabetes are common consequences of changing lifestyles (increased sedentary lifestyles and increased energy density of diets). Both are potentially preventable through lifestyle modification on a population level, but this requires a coherent and multifaceted strategy. Such strategies are not developed or implemented. These developments point toward the great urgency to develop global and national plans for adequate prevention and management of obesity and type 2 diabetes mellitus.

Keywords

ObesityInsulin resistanceDiabetesDiabetes mellitus
Type
Research Article
Information
British Journal of Nutrition , Volume 83 , Issue S1 , June 2000 , pp. S5 - S8
Copyright
Copyright © The Nutrition Society 2000

References

Egger, G & Swinburn, B (1997) An ‘ecological’ approach to the obesity pandemic. British Medical Journal 315, 477–480.CrossRefGoogle Scholar
Flegal, KM, Carroll, MD, Kuczmarski, RJ & Johnson, CL (1998) Overweight and obesity in the United States: prevalence and trends, 1960–1994. International Journal of Obesity 22, 39–47.CrossRefGoogle ScholarPubMed
Jeffery, RW & French, SA (1999) Preventing weight gain in adults: the pound of prevention study. American Journal of Public Health 89, 747–751.CrossRefGoogle ScholarPubMed
King, H, Aubert, RE & Herman, WH (1998) Global burden of diabetes 1995–2025. Prevalence, numerical estimates and projections. Diabetes Care 21, 1414–1431.CrossRefGoogle ScholarPubMed
Kosaka, K, Kuzuya, T, Yoshinaga, H & Hagura, R (1996) A prospective study of health check examinees for the development of non-isulin-dependent diabates mellitus: relationship of the incidence of diabetes with initial insulinogenic index and degree of obesity. Diabetic Medicine 13, S120-S126.CrossRefGoogle Scholar
Molarius, A, Seidell, JC, Sans, S, Tuomilehto, J & Kuulasmaa, K (2000) Educational level and relative body weight, and changes in their association over 10 years — an international perspective from the WHO MONICA project American Journal of Public Health.Google Scholar
Monteiro, CA, Benicio, MH, Conde, WL & Popkin, BM (2000) Shifting obesity trends in Brazil European Journal of Clinical Nutrition.Google Scholar
Pietinen, P, Vartiainen, E, Seppanen, R, Aro, A & Puska, P (1996) Changes in diet in Finland from 1972 to 1992: impact on coronary heart disease risk. Preventive Medicine 25, 243–250.CrossRefGoogle ScholarPubMed
Pietinen, P, Vartiainen, E & Mannisto, S (1996) Trends in body mass index and obesity among adults in Finland from 1972 to 1992. International Journal of Obesity 20, 114–120.Google ScholarPubMed
Popkin, BM, Keyou, G, Fengying, Z, Guo, X, Haijiang, M & Zohoori, N (1993) The nutrition transition in China: a cross-sectional analysis. European Journal of Clinical Nutrition 47, 333–346.Google Scholar
Seidell, JC (1998) Time trends in obesity: an epidemiological perspective. Hormone and Metabolic Research 21, 155–158.Google Scholar
Seidell, JC (1999) Prevention of obesity: the role of the food industry. Nutrition Metabolism and Cardiovascular Disease 9, 45–50.Google ScholarPubMed
Seidell, JC (1999) The burden of obesity and its sequelae. Disease Management and Health Outcomes 5, 13–21.CrossRefGoogle Scholar
Seidell, JC (1999) Optimizing fat intake: does a reduction in fat intake prevent obesity? European Heart Journal S118–S122.Google Scholar
Seidell, JC & Rissanen, A (1998) Time trends in the worldwide prevalence of obesity. In Handbook of Obesity, pp. 79–91 [GA, Bray, C, Bouchard, WPT, James, editors]. New York, NY: Marcel Dekker.Google Scholar
Vartiainen, E, Puska, P, Pekkanen, J, Tuomilehto, J & Jousilahti, P (1994) Changes in risk factors explain changes in mortality from ischaemic heart disease in Finland. British Medical Journal 309, 23–27.CrossRefGoogle ScholarPubMed
Vartiainen, E, Sarti, C, Tuomilehto, J & Kuuulasmaa, K (1995) Do changes in cardiovascular risk factors explain changes in mortality from stroke in Finland?. British Medical Journal 310, 901–904.CrossRefGoogle ScholarPubMed
Wannamethee, SG & Shaper, AG (1999) Weight change and duration of overweight and obesity in the incidence of type 2 diabetes. Diabetes Care 22, 1266–1272.CrossRefGoogle ScholarPubMed
WHO (1998 a) The World Health Report 1998. Life in the 21st Century — a Vision for All.Geneva, Switzerland:WHO.Google Scholar
WHO (1998 b) Obesity — Preventing and Managing the Global Epidemic.Geneva, Switzerland:WHO.Google Scholar
Williamson, DF (1996) The effectiveness of community-based health education trials for the control of obesity. In Progress in Obesity Research 7, pp. 331–335 [Angel, A , Anderson, H , Bouchard, C et al. , editors]. London, UK: J. Libbey & Co.Google Scholar
Wolf, MA & Colditz, GA (1998) Current estimates of the economic cost of obesity in the United States. Obesity Research 6, 97–106.CrossRefGoogle ScholarPubMed