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The nitrogen-sparing effect of methionine sulphoxide and some other sulphur-containing amino acids

Published online by Cambridge University Press:  09 March 2007

L. R. Njaa
Affiliation:
Government Vitamin Institute, Directorate of Fisheries, 5013 Bergen, Norway
A. Aksnes
Affiliation:
Government Vitamin Institute, Directorate of Fisheries, 5013 Bergen, Norway
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Abstract

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1. The nitrogen-sparing effect of methionine, methionine sulphoxide, homocystme, cystine and choline was studied in rats by determining daily N excretions during 5 d after changing from a high-protein diet to a protein-free diet, L-glutamic acid was used as a negative control.

2. L-, D- and DL-methionine were equally active in sparing N. L-methionine sulphoxide, DL-homocystine and L-cystine were as active as L-methionine. D-methionine sulphoxide was slightly less active than L-methionine sulphoxide, Choline hydrogen tartrate was not different from the negative control.

3. It is concluded that in short-term experiments cystine is the key substance in the N-sparing effect.

Type
Papers on General Nutrition
Copyright
Copyright © The Nutrition Society 1982

References

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