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Metabolic effects of a mixed and a high-carbohydrate low-fat diet in man, measured over 24 h in a respiration chamber

Published online by Cambridge University Press:  24 July 2007

M. Hurni ,
B. Burnand ,
PH. Pittet  and
E. Jequier
M. Hurni
Affiliation:
Institute of Physiology, University of Lausanne, 7 Rue de Bugnon, 1011 Lausanne, Switzerland
B. Burnand
Affiliation:
Institute of Physiology, University of Lausanne, 7 Rue de Bugnon, 1011 Lausanne, Switzerland
PH. Pittet
Affiliation:
Institute of Physiology, University of Lausanne, 7 Rue de Bugnon, 1011 Lausanne, Switzerland
E. Jequier
Affiliation:
Institute of Physiology, University of Lausanne, 7 Rue de Bugnon, 1011 Lausanne, Switzerland
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Abstract

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1. The relation between dietary carbohydrate:lipid ratio and the fuel mixture oxidized during 24 h was investigated in eleven healthy volunteers (six females, and five males) in a respiration chamber. Values of the fuel mixture oxidized were estimated by continuous indirect calorimetry and urinary nitrogen measurements.

2. The subjects were first given a mixed diet for 7 d and spent the last 24 h of the 7 d period in a respiration chamber for continuous gas-exchange measurement. The fuels oxidized during 2·5 h of moderate exercise were also measured in the respiration chamber. After an interval of 2 weeks from the end of the mixed-diet period, the same subjects were given an isoenergetic high-carbohydrate low-fat diet for 7 d, and the same experimental regimen was repeated.

3. Dietary composition markedly influenced the fuel mixture oxidized during 24 h and this effect was still present 12 h after the last meal in the postabsorptive state. However, the diets had no influence on the substrates oxidized above resting levels during exercise. With both diets, the 24 h energy balance was slightly negative and the energy deficit was covered by lipid oxidation.

4. With the high-carbohydrate low-fat diet, the energy expenditure during sleep was found to be higher than that with the mixed diet.

5. It is concluded that: (a) the composition of the diet did not influence the fuel mixture utilized for moderate exercise, (b) the energy deficit calculated for a 24 h period was compensated by lipid oxidation irrespective of the carbohydrate content of the diet, (c) energy expenditure during sleep was found to be higher with the high-carbohydrate low-fat diet than with the mixed diet.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 47 , Issue 1 , January 1982 , pp. 33 - 43
Copyright
Copyright © The Nutrition Society 1982

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