Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-30T20:19:39.189Z Has data issue: false hasContentIssue false
  • English
  • Français

Megadosage of ascorbic acid in an Antarctic expedition

Published online by Cambridge University Press:  06 August 2007

P. J. Gormly
P. J. Gormly
Affiliation:
Australian National Antarctic Research Expeditions 1973, Casey, Antarctica
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. No difference in health was observed between men on megadosage of ascorbic acid and controls during the year of an Antarctic expedition.

2. All men appeared to have a satisfactory intake of ascorbic acid throughout the year.

3. There was a statistically significant decrease in excretion of ascorbic acid by men on megadosage over the year, and by the controls.

4. The decline in excretion by the control group may be explained by dietary change, but the decline in those on megadosage may be due to altered handling of ascorbic acid by the body.

5. No complications due to megadosage of ascorbic acid were observed.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 37 , Issue 2 , March 1977 , pp. 269 - 277
Copyright
Copyright © The Nutrition Society 1977

References

REFERENCES

Abbasy, M. A., Harris, L. J., Ray, S. N. & Marrack, J. R. (1935). Lancet ii, 1399.CrossRefGoogle Scholar
Adams, R. J., Stanmeyer, W. R. & Harding, R. S. (1962). J. dent. Med. 17, 36.Google Scholar
Allen, T. R., Bradburne, A. F., Stott, E. J., Goodwin, C. S. & Tyrrell, D. A. J. (1973). J. Hyg., Camb. 71, 657.Google Scholar
Atkinson, E. L. (1915). J. R. nav. med. Serv. 1, 1.CrossRefGoogle Scholar
Baker, E. M. (1967). Am. J. clin. Nutr. 20, 583.CrossRefGoogle Scholar
Bartley, W. H., Krebs, H. A. & O'Brien, J. R. P. (1953). Spec. Rep. Ser. Med. res. Coun., Lond. no. 280.Google Scholar
Cochrane, W. A. (1965). Can. med. Ass. J. 93, 893.Google Scholar
Cohen, M. M. & Duncan, A. M. (1967). Br. med. J. 4, 516.CrossRefGoogle Scholar
Csordas, S. E. (1958). J. diet. Ass., Victoria. 10, 1.Google Scholar
Dugal, L.-P. (1961). Ann. N. Y. Acad. Sci. 92, 307.CrossRefGoogle Scholar
Dugal, L.-P. & Thérien, M. (1947). Can. J. Res., E. 25, 111.CrossRefGoogle Scholar
Evans, E. R. G. (1937). J. R. nav. med. Serv. 23, 14.CrossRefGoogle Scholar
Glickman, N., Keeton, R. W., Mitchell, H. H. & Fahnestock, M. K. (1946). Am. J. Physiol. 146, 538.CrossRefGoogle Scholar
Goldsmith, G. A. (1961). Ann. N.Y. Acad. Sci. 92, 230.CrossRefGoogle Scholar
Harris, L. J. & Ray, S. N. (1935). Lancet i, 71.CrossRefGoogle Scholar
Hodges, R. E., Baker, E. M., Hood, J., Sauberlich, H. E. & March, S. C. (1969). Am. J. clin. Nutr. 22, 535.CrossRefGoogle Scholar
Kark, R. M., Croome, R. R. M., Cawthorpe, J., Bell, D. M., Bryans, A., Macbeth, R. J., Johnson, R. E., Consolazio, F. C., Poulin, J. L., Taylor, F. H. L. & Cogswell, R. C. (1948). J. appl. Physiol. 1, 73.CrossRefGoogle Scholar
Kefford, J. F. (1956). C.S.I.R.O. Fd Preserv. Quart. 16, 47.Google Scholar
Kendall, E. J. C. (1954). Polar Record. 7, 467.CrossRefGoogle Scholar
Law, P. G. (1957). Nutrition in the Antarctic. 13 pp. Sydney: Roy. Aust. Coll. Physicians.CrossRefGoogle ScholarPubMed
Lee, R. I. & White, P. D. (1913). Am. J. Med. Sci. 145, 495.CrossRefGoogle Scholar
Lewis, H. E. (1972). Proc. R. Soc. Med. 65, 39.Google Scholar
Macklin, A. H. (1923). In Shackleton's Last Voyage pp. 352–365 [Wild, F. editor], London: Cassell.Google Scholar
Nour-Eldin, F. (1972). Haematology, Practical and Clinical, p. 169,Sevenoaks, Kent: Butterworths.Google Scholar
Paleyev, N. R. (1964). In Proc. IIIrd Int. Biometeorol. Congr. Pau, France. 1963, p. 840 [Tromp, S. W. and Weike, W. H., editors]. Oxford: Pergamon Press.Google Scholar
Pauling, L. (1970). Vitamin C and The Common Cold. San Francisco: Freeman & Co.Google Scholar
Pelletier, O. (1968). Am. J. clin. Nutr. 21, 1259.CrossRefGoogle Scholar
Perlitsh, M. J., Nielsen, A. G. & Stanmeyer, W. R. (1961). J. dent. Res. 40, 789.CrossRefGoogle Scholar
Priestley, R. (1956). Nature, Lond. 178, 463.CrossRefGoogle Scholar
Ralli, E. P. & Sherry, S. (1941). Medicine 20, 251.CrossRefGoogle Scholar
Rhead, W. J. & Schrauzer, G. N. (1971). Nutr. Rev. 29, 262.Google Scholar
Rodahl, K. (1954). J. Nutr. 53, 575.CrossRefGoogle Scholar
Ryabinin, I. F. & Afanas'yef, Yv.F. (1969). Soviet Antarctic Exped. Inform. Bull. 7, 373.Google Scholar
Schrauzer, G. N. & Rhead, W. J. (1973). Int. J. vitam. Nutr. Res. 43, 201.Google Scholar
Shamis, A. Ya. (1971). Trans. Soviet Antarctic Exped. 49, 391.Google Scholar
Soucek, F. (1963). Report on Physiology – Wilkes, 1962. Unpublished Antarctic Division Report, Melbourne: Department of Science.Google Scholar
Storvick, C. A. & Hauck, H. M. (1942). J. Nutr. 23, 111.CrossRefGoogle Scholar
Van der Merwe, A., le, R. (1962). S. Afr. med. J. 36, 751.Google Scholar
Vilter, R. W. (1967). In The Vitamins, Chemistry, Physiology, Pathology, Methods, pp. 471–473 [Sebrell, W. H. and Harris, R. S., editors]. N.Y.: Academic Press.Google Scholar
Wilson, O. (1965). In Biogeography and Ecology in Antarctica, p. 703. [Van Oye, P. and Van Mieghem, J., editors]. The Hague: Dr W. Junk.Google Scholar
Wilson, M. G. & Lubschez, R. (1946). J. clin. Invest. 25, 428.CrossRefGoogle Scholar