Hostname: page-component-cd9895bd7-gbm5v Total loading time: 0 Render date: 2024-12-23T15:37:58.007Z Has data issue: false hasContentIssue false
  • English
  • Français

Lysozyme activity in plasma and leucocytes in malnourished children

Published online by Cambridge University Press:  24 July 2007

M. Mohanram ,
Vinodini Reddy  and
S. Mishra
M. Mohanram
Affiliation:
National Institute of Nutrition, Indian Council of Medical Research, Jamai-Osmania, Hyderabad-500007, India
Vinodini Reddy
Affiliation:
National Institute of Nutrition, Indian Council of Medical Research, Jamai-Osmania, Hyderabad-500007, India
S. Mishra
Affiliation:
National Institute of Nutrition, Indian Council of Medical Research, Jamai-Osmania, Hyderabad-500007, India
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Lysozyme activity was estimated in plasma and leucocytes of twelve children suffering from kwashiorkor, thirteen children with ocular signs of vitamin A deficiency and ten apparently normal children acting as controls.

2. The results showed that the activity of lysozyme in leucocytes was significantly reduced in children with kwashiorkor and in vitamin A-deficient children. Following therapy, the levels of the enzyme in leucocytes were restored to normal.

3. The initial enzyme activity in the plasma of both groups of children did not differ significantly from the control value, and was not significantly changed after treatment.

4. It is suggested that the decreased activity of lysozyme is one of the factors responsible for diminished resistance to infection generally observed in malnourished children.

Type
Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 32 , Issue 2 , September 1974 , pp. 313 - 316
Copyright
Copyright © The Nutrition Society 1974

References

REFERENCES

Balmer, S. E. & Rutishauser, I. H. E. (1968). J. Pediat. 73, 783.CrossRefGoogle Scholar
Cohn, Z. A. & Hirsch, J. G. (1960). J. exp. Med. 112, 1015.Google Scholar
Davis, S. D., Gemsa, D., Iannetta, A. & Wedgwood, R. J. (1968). J. Immun. 101, 277.CrossRefGoogle Scholar
Dean, R. F. A. & Schwartz, R. (1953). Br. J. Nutr. 7, 131.Google Scholar
Dingle, J. T., Sharman, I. M. & Moore, T. (1966). Biochem. J. 98, 476.CrossRefGoogle Scholar
Edozien, J. C. (1961). Pediatrics, Springfield 27, 325.CrossRefGoogle Scholar
Ermol'eva, Z. Y., Furer, N. M., Ravich, I. V., Navashin, S. M., Braude, A. I., Fomina, I. P., Zhukovskaya, N. A., Balezina, T. I., Ved'mina, E. A., Golosova, T. V., Nemirovskaya, B. M. & Terent'eva, T. G. (1964). Fedn Proc. Fedn Am. Socs exp. Biol. 23, T75.Google Scholar
Gopalan, C., Venkatachalam, P. S. & Belavady, B. (1960). Am. J. clin. Nutr. 8, 833.Google Scholar
Gordis, L. (1966). J. Pediat. 68, 638.CrossRefGoogle Scholar
Guha, A. & Roels, O. A. (1965). Biochim. biophys. Acta 111, 364.CrossRefGoogle Scholar
Harrison, J. F., Lunt, G. S., Scott, P. & Blainey, J. D. (1968). Lancet i, 371.Google Scholar
Mohanram, M. & Srikantia, S. G. (1967). Clin. Sci. 32, 215.Google Scholar
Mukherjee, K. L. & Sarkar, N. K. (1958). Br. J. Nutr. 12, 1.CrossRefGoogle Scholar
Oser, B. L. (1965). Hawk's Physiological Chemistry, 14th ed., pp. 1081, 1219. New York: McGraw-Hill.Google Scholar
Reddy, V. & Mohanram, M. (1971). Int. Z. VitamForsch. 41, 321.Google Scholar
Reindorp, S. & Whitehead, R. G. (1971). Br. J. Nutr. 25, 273.Google Scholar
Schwartz, R. (1956). J. clin. Path. 9, 333.Google Scholar
Selvaraj, R. J. & Bhat, K. S. (1972 a). Biochem. J. 127, 255.CrossRefGoogle Scholar
Selvaraj, R. J. & Bhat, K. S. (1972 b). Am. J. clin. Nutr. 25, 166.CrossRefGoogle Scholar
Srinivasan, P. R. & Patwardhan, V. N. (1952). Lancet ii, 864.Google Scholar
Waterlow, J. C. (1950). Lancet i, 908.CrossRefGoogle Scholar