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Level of nutrition and visceral organ size and metabolic activity in sheep*

Published online by Cambridge University Press:  09 March 2007

D. G. Burrin ,
C. L. Ferrell ,
R. A. Britton  and
Marc Bauer
D. G. Burrin
Affiliation:
Department of Animal Science, University of Nebraska, Lincoln, Nebraska 68583-0908, USA
C. L. Ferrell
Affiliation:
Roman L. Hruska Meat Animal Research Center, Agricultural Research Service, USDA, Clay Center, Nebraska, USA
R. A. Britton
Affiliation:
Department of Animal Science, University of Nebraska, Lincoln, Nebraska 68583-0908, USA
Marc Bauer
Affiliation:
Department of Animal Science, University of Nebraska, Lincoln, Nebraska 68583-0908, USA
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Abstract

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Thirty-two crossbred wether lambs (initial live-weight 31 kg) were fed on a diet (metabolizable energy (ME) 12.8 MJ/kg) ad lib. (ADLIB) or restricted to maintain body-weight (MAINT) for a 21 d period. On days 0, 7, 14 and 21, four lambs per treatment were slaughtered, visceral organs weighed and tissues sampled. During the 21 d period, ME intake in ADLIB lambs increased quadratically with an average rate of live-weight gain of 425 g/d. In MAINT lambs, live weight (30 kg) was maintained, and daily ME intake (kJ/kg empty body-weight (EBW)0.75) declined (P < 0.01) quadratically with time. Weights of liver, stomach and small intestines as a percentage of EBW were increased in ADLIB lambs and decreased by 10–33 % in MAINT lambs (treatment × day, P < 0.01). In vitro liver oxygen consumption was not affected by level of feed intake. Estimates of whole-liver O2 consumption (mmol O2/d per kg EBW) increased in ADLIB lambs and were relatively constant in MAINT lambs. These findings suggest that level of feed intake changes the relative proportion of visceral organs to body mass. In addition, the effect of level of feed intake on changes in the relative contribution of visceral organs to whole-body metabolic rate appears to be primarily a result of differences in organ size rather than tissue-specific metabolic activity.

Keywords

Nutrient restrictionOrgan size and metabolismSheep
Type
Energy Metabolism
Information
British Journal of Nutrition , Volume 64 , Issue 2 , September 1990 , pp. 439 - 448
Copyright
Copyright © The Nutrition Society 1990

References

Basset, J. M. (1974). Diurnal patterns of plasma insulin, growth hormone, corticosteroid and metabolite concentrations in fed and fasted sheep. Australian Journal of Biological Science 27, 167–181.CrossRefGoogle Scholar
Bergman, E. N. (1974). Production and utilization of metabolites by the alimentary tract as measured in portal and hepatic blood. In Digestion and Metabolism in Ruminants, pp. 292–305 [McDonald, I. W. and Warner, A. C. I., editors]. Armidale, NSW: University of New England Publishing Unit.Google ScholarPubMed
Blum, J. W., Gingins, M., Vitins, P. & Bickel, H. (1980). Thyroid hormone levels related to energy and nitrogen balance during weight loss and regain in adult sheep. Acta Endocrinologica 93, 440–447.Google Scholar
Blum, J. W., Schnyder, W., Kunz, P. L., Blom, A. K., Bickel, H. & Schurch, A. (1985). Reduced and compensatory growth: endocrine and metabolic changes during food restriction and refeeding in steers. Journal of Nutrition 115, 417–424.CrossRefGoogle ScholarPubMed
Blum, J. W., Thomson, E. F. & Bickel, H. (1979). Alterations of serum triiodothyronine levels during reduced and compensatory growth of steers. Zeitschrift für Tierphysiologie, Tierernährung and Futtermittelkunde 42, 711.CrossRefGoogle ScholarPubMed
Burrin, D. G., Britton, R. L. & Ferrell, C. L. (1988). Visceral organ size and hepatocyte metabolic activity in fed and fasted rats. Journal of Nutrition 118, 15471552.CrossRefGoogle ScholarPubMed
Burrin, D. G., Ferrell, C. L., Eisemann, J. H., Britton, R. A. & Nienaber, J. A. (1989). Effect of level of nutrition on splanchnic blood flow and oxygen consumption in sheep. British Journal of Nutrition 62, 23–34.CrossRefGoogle ScholarPubMed
Canas, R., Romero, J. J. & Baldwin, R. L. (1982). Maintenance energy requirements during lactation in rats. Journal of Nutrition 112, 1876–1880.CrossRefGoogle ScholarPubMed
Davis, S. R., Barry, T. N. & Hughson, G. A. (1981). Protein synthesis in tissues of growing lambs. British Journal of Nutrition 46, 409–419.CrossRefGoogle ScholarPubMed
DeJong, A. (1981). The effect of feed intake on nutrient and hormone levels in jugular and portal blood of goats. Journal of Agricultural Science, Cambridge 96, 643–657.CrossRefGoogle Scholar
Ferrell, C. L. & Koong, L. J. (1985). Response of body organs of lambs to differing nutritional treatments. In Energy Metabolism of Farm Animals. Proceedings of the 10th Symposium, European Association of Animal Production. Publication no. 32, pp. 26–29 [Moe, P. W., Tyrell, H. F. and Reynolds, P. J., editors]. Totowa, New Jersey: Roman & Littlefield.Google Scholar
Ferrell, C. L. & Koong, L. J. (1986). Influence of plane of nutrition on body composition, organ size and energy utilization of Sprague-Dawley rats. Journal of Nutrition 116, 2525–2535.CrossRefGoogle ScholarPubMed
Ferrell, C. L., Koong, J. L. & Nienaber, J. A. (1986). Effect of previous nutrition on body composition and maintenance energy costs of growing lambs. British Journal of Nutrition 56, 595–605.CrossRefGoogle ScholarPubMed
Gray, R. & McCracken, K. J. (1979). Plane of nutrition and the maintenance requirement. In Energy Metabolism of Farm Animals. Proceedings of the 8th Symposium, European Association of Animal Production. Publication no. 26, pp. 163–167 [Mount, L. E., editor]. London: Butterworths.Google Scholar
Huntington, G. B. (1984). Relationship of portal blood flow to metabolizable energy intake of cattle. Canadian Journal of Animal Science 64 (Suppl.), 16–17.CrossRefGoogle Scholar
Huntington, G. B., Varga, G. A., Reynolds, P. J. & Tyrrell, H. F. (1985). Net absorption of nutrients and oxygen consumption by portal-drained viscera in relation to energy metabolism by Holstein cattle. In Energy Metabolism of Farm Animals. Proceedings of the 10th Symposium. European Association of Animal Production. Publication no. 32, pp. 22–25 [Moe, P. W., Tyrrell, H. F. and Reynolds, P. J., editors]. Totowa, NJ: Roman & Littlefield.Google Scholar
Ingram, D. J. & Ramsden, D. B. (1981). The influence of energy intake on the metabolism of 3,5,3'- triiodothyronine and 3,3',5',-triiodothyronine in young pigs. Journal of Endocrinology 88, 141–146.CrossRefGoogle Scholar
Jenkins, T. G. & Ferrell, C. L. (1983). Nutrient requirements to maintain weight of mature, non-lactating, non-pregnant cows of four diverse breed types. Journal of Animal Science 56, 761–770.CrossRefGoogle Scholar
Jenkins, T. G., Ferrell, C. L. & Cundiff, L. V. (1986). Relationship of components of the body among mature cows as related to size, lactation potential and possible effects on productivity. Animal Production 43, 245–254.Google Scholar
Koong, L. J., Neinaber, J. A., Pekas, J. C. & Yen, J. T. (1982). Effects of plane of nutrition on organ size and fasting heat production in pigs. Journal of Nutrition 112, 1638–1642.CrossRefGoogle ScholarPubMed
Ledger, H. P. & Sayers, A. R. (1977). The utilization of dietary energy by steers during periods of restricted food intake and subsequent realimentation. I. The effect of time on maintenance requirements of steers held at constant live weights. Journal of Agricultural Science, Cambridge 88, 11–26.CrossRefGoogle Scholar
McBride, B. W. & Milligan, L. P. (1985 a). Magnitude of ouabain-sensitive respiration in the liver of growing, lactating and starved sheep. British Journal of Nutrition 54, 293–303.CrossRefGoogle ScholarPubMed
McBride, B. W. & Milligan, L. P. (1985 b). Influence of feed intake and starvation on the magnitude of Na+-K+- ATPase-dependent respiration in duodenal mucosa of sheep. British Journal of Nutrition 53, 605–614.Google Scholar
McNurlan, M. A., Tomkins, A. M. & Garlick, P. J. (1979). The effect of starvation on the rate of protein synthesis in rat liver and small intestines. Biochemical Journal 178, 373–379.CrossRefGoogle Scholar
Marston, H. R. (1948). Energy transactions in sheep. I. The basal heat production and the heat increment. Australian Journal of Science Research B1, 91–129.Google Scholar
Mersmann, H. J. (1986). Comparison of plasma free-fatty-acid and blood-glycerol concentrations with measurement of lipolysis in porcine adipose tissue in vitro. Journal of Animal Science 63, 757–769.Google Scholar
Meyer, J. H. & Clawson, W. J. (1964). Undernutrition and subsequent realimentation in rats and sheep. Journal of Animal Science 23, 214–224.CrossRefGoogle Scholar
Milligan, L. P. & Summers, M. (1986). The biological basis of maintenance and its relevance to assessing response to nutrients. Proceedings of the Nutrition Society 45, 185–193.CrossRefGoogle Scholar
Millward, D. J., Garlick, P. J. & Reeds, P. J. (1976). The energy costs of growth. Proceedings of the Nutrition Society 35, 339–349.CrossRefGoogle Scholar
National Research Council (1984). Nutrient Requirements of Beef Cattle. Washington, DC: National Academy Press.Google Scholar
Reynolds, C. K. & Tyrrell, H. F. (1987). Effect of diet intake level on net visceral tissue metabolism in growing beef heifers. Journal of Animal Science 65 (Suppl. 1), 477.Google Scholar
SAS (1982). SAS User's Guide: Statistics. Cary, NC: Statistical Analysis System Institute Inc.Google Scholar
Smith, N. E. & Baldwin, R. L. (1974). Effects of breed, pregnancy and lactation on weight of organs and tissues in dairy cattle. Journal of Dairy Science 57, 1055–1060.CrossRefGoogle Scholar
Tata, J. R., Ernster, L., Lindberg, O., Arrhenius, E., Pedersen, D. & Hedman, R. (1963). The action of thyroid hormones at the cell level. Biochemical Journal 86, 408–428.CrossRefGoogle ScholarPubMed
Webster, A. J. F. (1981). The energetic efficiency of metabolism. Proceedings of the Nutrition Society 40, 121–128.CrossRefGoogle ScholarPubMed
Webster, A. J. F., Osuji, P. O., White, F. & Ingram, J. F. (1975). The influence of food intake on portal blood flow and heat production in the digestive tract of sheep. British Journal of Nutrition 34, 125–139.CrossRefGoogle ScholarPubMed
Wieghart, M., Sleptis, R., Elliot, J. M. & Smith, D. F. (1986). Glucose absorption and hepatic gluconeogenesis in dairy cows fed diets varying in forage content. Journal of Nutrition 116, 839–850.Google Scholar