Hostname: page-component-cd9895bd7-lnqnp Total loading time: 0 Render date: 2024-12-25T02:54:12.288Z Has data issue: false hasContentIssue false
  • English
  • Français

Kinetics of pancreatic juice secretion in relation to duodenal migrating myoelectric complex in preruminant and ruminant calves fed twice daily

Published online by Cambridge University Press:  09 March 2007

Romuald Zabielski ,
Paweł Kiela ,
Violetta Leśniewska ,
Ryszard Krzemiński ,
Marioletta Mikołajczyk  and
Wiesław Barej
Romuald Zabielski
Affiliation:
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, ul. Nowoursynowska 166, 02-787 Warsaw, Poland
Paweł Kiela
Affiliation:
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, ul. Nowoursynowska 166, 02-787 Warsaw, Poland
Violetta Leśniewska
Affiliation:
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, ul. Nowoursynowska 166, 02-787 Warsaw, Poland
Ryszard Krzemiński
Affiliation:
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, ul. Nowoursynowska 166, 02-787 Warsaw, Poland
Marioletta Mikołajczyk
Affiliation:
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, ul. Nowoursynowska 166, 02-787 Warsaw, Poland
Wiesław Barej
Affiliation:
Department of Animal Physiology, Faculty of Veterinary Medicine, Warsaw Agricultural University, ul. Nowoursynowska 166, 02-787 Warsaw, Poland
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Daily secretion of pancreatic juice, including postprandial responses to food, was investigated in two groups of calves: preruminant (fed with liquid food) and ruminant (fed with solid food). Male Friesian calves (1 week old and 6 weeks old) were surgically fitted with a pancreatic duct catheter, duodenal cannula and two duodenal electrodes. Continuous 24 h collections of pancreatic juice and myoelectrical recordings were performed with minimal restraint and disturbance of animals. In both groups of calves clear periodic fluctuations in pancreatic juice secretion (volume, protein output and trypsin activity) coinciding with duodenal migrating myoelectric complexes (MMC) were recorded. Secretion of juice per cycle and per day was greater in ruminant calves, but the frequency and amplitude of cycles were lower in this group. There were no differences between day and night-time preprandial pancreatic cycles and duodenal MMC in preruminant calves, whilst in ruminant calves, evening MMC were longer than morning MMC. The pancreatic cephalic phase (increase of volume flow, protein output and trypsin activity during and just after food intake) was significant only in preruminant calves following morning feeding. Postprandial pancreatic cycles did not differ from preprandial cycles, except the pancreatic cycle (juice volume and trypsin activity) in which food was offered in preruminant calves. No gastric or intestinal phase was observed in either group of calves. In conclusion, biological cycles of the gastrointestinal tract are present in both preruminant and ruminant calves, and these cycles evolve along with the change from liquid to solid food.

Keywords

PancreasDuodenumMyoelectrical activityCalf
Type
Animal Nutrition
Information
British Journal of Nutrition , Volume 78 , Issue 3 , September 1997 , pp. 427 - 442
Copyright
Copyright © The Nutrition Society 1997

References

REFERENCES

Abello, J., Laplace, J. P. & Corring, T. (1988) Biliary and pancreatic secretory component of the migrating myoelectric complex in the pig. Effect on intraduodenal pH. Reproduction, Nutrition, Développement 28, 953–967.CrossRefGoogle ScholarPubMed
Boldyreff, W. (1911) Einige neue Seiten der Tatigeit des Pancreas (Some new features of pancreatic function). Ergebnisse der Physiologie 11, 121–217.CrossRefGoogle Scholar
Erlanger, B. F., Kokowsky, N. & Cohen, W. (1961) The preparation and properties of two new chromogenic substrates of trypsin. Archives of Biochemistry and Biophysics 95, 271–278.CrossRefGoogle ScholarPubMed
Girard, C. L. & Sissons, J. W. (1992) The role of migrating myoelectric complexes in the regulation of digesta transport in the preruminant calf. Canadian Journal of Physiology and Pharmacology 70, 1142–1147.CrossRefGoogle ScholarPubMed
Guilloteau, P., Corring, T., Garnot, P., Martin, P., Toullec, R. & Durand, G. (1983) Effects of age and weaning on enzyme activity of abomasum and pancreas of the lamb. Journal of Dairy Science 66, 2373–2385.Google Scholar
Guilloteau, P., Le Huërou-Luron, I., Chayvialle, J. A., Moutas, A., Bernard, C., Cuber, J. C., Burton, J., Puigserver, A. & Toullec, R. (1992) Plasma and tissue levels of digestive regulatory peptides during postnatal development and weaning in the calf. Reproduction, Nutrition, Développement 32, 285–296.CrossRefGoogle ScholarPubMed
Gullo, L., Pezzilli, R., Priori, P., Baldoni, F., Paparo, F. & Mattioli, G. (1987) Pure pancreatic juice collection over 24 consecutive hours. Pancreas 2, 620–623.CrossRefGoogle ScholarPubMed
Itoh, Z., Honda, R. & Hiwatashi, K. (1980) Biphasic secretory response of exocrine pancreas to feeding. American Journal of Physiology 238, G332–G337.Google ScholarPubMed
Kato, S., Katoh, K. & Barej, W. (1991). Regulation of exocrine pancreatic secretion in ruminants. In Physiological Aspects of Digestion and Metabolism in Ruminants, pp. 89–109 [Tsuda, T., Sasaki, Y. and Kawashima, R., editors]. San Diego, CA: Academic Press Inc.CrossRefGoogle Scholar
Kato, S., Usami, M. & Ushijima, J. (1984) The effect of feeding on pancreatic exocrine secretion in sheep. Japanese Journal of Zootechnical Science 55, 973–977.Google Scholar
Kellow, J. E., Eckersley, G. M. & Jones, M. (1992) Enteric and central contributions to intestinal dysmotility in irritable bowel syndrome. Digestive Diseases and Sciences 37, 168–174.CrossRefGoogle ScholarPubMed
Kiela, P. (1996). Integrative role of some intestinal bioactive peptides in the regulation of pancreatic exocrine secretion and the MMC of the stomach and small intestine in piglets. PhD Thesis in Veterinary Medicine, Warsaw Agricultural University.Google Scholar
Kiela, P., Zabielski, R., Podgurniak, P., Midura, M., Barej, W., Gregory, P. C. & Pierzynowski, S. G. (1996) Cholecystokinin-8 and Vasoactive Intestinal Polypeptide stimulate exocrine pancreatic secretion via duodenal mediated mechanisms in the conscious pig. Experimental Physiology 81, 375–384.Google Scholar
Konturek, S. J., Thor, P. J., Bilski, J., Bielański, W. & Laskiewicz, J. (1986) Relationships between duodenal motility and pancreatic secretion in fasted and fed dogs. American Journal of Physiology 250, G570–G574.Google ScholarPubMed
Kumar, D., Soffer, E. E., Wingate, D. L., Britto, J., Das-Gupta, A. & Mridha, K. (1989) Modulation of the duration of human postprandial motor activity by sleep. American Journal of Physiology 256, G851–G855.Google Scholar
Le Huërou, I., Wicker, C., Guilloteau, P., Toullec, R. & Puigserver, A. (1990) Specific regulation of the gene expression of some pancreatic enzymes during postnatal development and weaning in the calf. Biochimica et Biophysica Acta 1048, 257–264.CrossRefGoogle ScholarPubMed
Le Huërou-Luron, I., Le Drean, G., Chayvialle, J. A., Bernard, C., Rome, V., Toullec, R. & Guilloteau, P. (1994) Are secretin and cholecystokinin (CCK) involved in the regulation of postprandial pancreatic juice secretion in preruminant calves? Preliminary results concerning juice flow and protein concentration and plasma regulatory peptides levels. Proceedings of the Society of Nutrition Physiology 3, 298.Google Scholar
Le Huërou-Luron, I., Le Drean, G., Chayvialle, J. A., Rome, V., Bernard, C., Toullec, R. & Guilloteau, P. (1995). Daily pancreatic secretion and its relation with CCK, gastrin and secretin plasmatic levels in ruminant calves. Preliminary results. Annales de Zootechnie 44, Suppl., 282.CrossRefGoogle Scholar
Le Meuth, V., Farjaudon, N., Bawab, W., Chastre, E., Rosselin, G., Guilloteau, P. & Gespach, C. (1991) Characterization of binding sites for VIP-related peptides and activation of adenylate cyclase in developing pancreas. American Journal of Physiology 260, G265–G274.Google ScholarPubMed
Le Meuth, V., Philouze-Rome, V., Le Huërou-Luron, I., Formal, M., Vaysse, N., Gespach, C., Guilloteau, P. & Fourmy, D. (1993) Differential expression of A- and B-subtypes of cholecystokinin/gastrin receptors in the developing calf pancreas. Endocrinology 133, 1182–1191.CrossRefGoogle ScholarPubMed
Liddle, R. A. (1994). Cholecystokinin. In Gut Peptides: Biochemistry and Physiology. [Walsh, J.H. and Dockray, G. J., editors]. New York: Raven Press.Google Scholar
Lowry, O. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. (1951) Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry 193, 165–175.CrossRefGoogle ScholarPubMed
Magee, D. F. & Naruse, S. (1983) Neural control of periodic secretion of the pancreas and the stomach in fasting dogs. Journal of Physiology 344, 153–160.CrossRefGoogle ScholarPubMed
Maouyo, D., Sarfati, P., Guan, D., Morisset, J. & Adelson, J. W. (1993) Circadian rhythm of exocrine pancreatic secretion in rats: major and minor cycles. American Journal of Physiology 264, G792–G800.Google ScholarPubMed
McCormick, R. J. & Stewart, W. E. (1966) Pancreatic secretion in the bovine calf. Journal of Dairy Science 50, 568–571.Google Scholar
Naranjo, J. A., Valverde, A., Martínez, de, Victoria, E., Mañas, M. & Moreno, J. (1986) Surgical preparation for the study of pancreatic exocrine secretion in the conscious preruminant goat. Laboratory Animals 20, 231–233.CrossRefGoogle Scholar
Nylander, A.-G., Chen, D., Ihse, I., Rehfeld, J. F. & Hakanson, R. (1992) Pancreatic atrophy in rats produced by the cholecystokinin-A receptor antagonist devazepide. Scandinavian Journal of Gastroenterology 27, 743–747.CrossRefGoogle ScholarPubMed
Onaga, T., Zabielski, R., Mineo, H. & Kato, S. (1993). The temporal coordination of interdigestive pancreatic exocrine secretion and intestinal migrating myoelectric complex in rats. In Proceedings of XXXII Congress of the International Union of Physiological Sciences, Glasgow, 95.1/P., p. 83. Glasgow: Internationl Union of Physiological Sciences Publications.Google Scholar
Pierzynowski, S. G., Weström, B. R., Svendsen, J. & Karlsson, B. W. (1990) Development of exocrine pancreas function in chronically cannulated pigs during 1–13 weeks of postnatal life. Journal of Pediatric Gastroenterology and Nutrition 10, 206–212.Google ScholarPubMed
Pierzynowski, S. G., Zabielski, R., Podgurniak, P., Kiela, P., Sharma, P., Weström, B. R., Kato, S. & Barej, W. (1992) Effects of reversible cold vagal blockade and atropinization on exocrine pancreas function during liquid food consumption in calves. Journal of Animal Physiology and Animal Nutrition 67, 268–273.CrossRefGoogle Scholar
Pierzynowski, S. G., Zabielski, R., Weström, B., Mikolajczyk, M. & Barej, W. (1991) Development of the exocrine pancreatic function in chronically cannulated calves from the preweaning period up to early rumination. Journal of Animal Physiology and Animal Nutrition 65, 165–172.CrossRefGoogle Scholar
Podgurniak, P. & Pierzynowski, S. G. (1993). Relation between the electrical activity of the duodenum and pancreatic juice secretion in calves. Chinese Medical Science Journal 8, Suppl., 75.Google Scholar
Ruckebusch, Y. (1975). Motility of the ruminant stomach associated with states of sleep. In Digestion and Metabolism in the Ruminant, pp. 77–90 [McDonald, W. and Warner, A.C. I., editors]. Armidale, Australia: The University of New England Publishing Unit.Google Scholar
Ruckebusch, Y. & Bueno, L. (1973) The effect of weaning on the motility of the small intestine in the calf. British Journal of Nutrition 30, 491–499.CrossRefGoogle ScholarPubMed
Ruckebusch, Y., Dardillat, C. & Guilloteau, P. (1983) Development of digestive functions in the newborn ruminant. Annales de Recherches Veterinaires 14, 360–374.Google ScholarPubMed
Shinohara, H., Williams, C., Yakabe, T. & Koldovsky, O. (1996) Epidermal growth factor delays gastric emptying and small intestinal transit in suckling rats. Pediatric Research 39, 281–286.CrossRefGoogle ScholarPubMed
Ternouth, J. H. & Buttle, H. L. (1973) Concurrent studies of the flow of digesta in the duodenum and of exocrine pancreatic secretion of calves. The collection of the exocrine pancreatic secretion from a duodenal cannula. British Journal of Nutrition 29, 387–397.CrossRefGoogle ScholarPubMed
Ternouth, J. H., Roy, J. H. B. & Shotton, S. M. (1976) Concurrent studies of the flow of digesta in the duodenum and of exocrine pancreatic secretion of calves. The effect of age. British Journal of Nutrition 36, 523–535.CrossRefGoogle ScholarPubMed
Thaela, M. J., Pierzynowski, S. G., Jensen, M. S., Jackobsen, K., Westrom, B. R. & Karlsson, B. W. (1995) The pattern of the circadian rhythm of pancreatic secretion in fed pigs. Journal of Animal Science 73, 3402–3408.CrossRefGoogle ScholarPubMed
Toullec, R., Chayvialle, J. A., Guilloteau, P. & Bernard, C. (1992) Early-life patterns of plasma gut regulatory peptide levels in calves. Effect of age, weaning and feeding. Comparative Biochemistry and Physiology 102A, 203–209.CrossRefGoogle Scholar
Vantrappen, G. R., Peeters, T. L. & Janssens, J. (1979) The secretory component of the interdigestive migrating motor complex in man. Scandinavian Journal of Gastroenterology 14, 663–667.CrossRefGoogle ScholarPubMed
Werner, H. T., Amarant, R. P., Millar, M., Fridkin, M. & Koch, Y. (1985) Immunoreactive and biologically active somatostatin in human and sheep milk. European Journal of Biochemistry 148, 353–357.CrossRefGoogle ScholarPubMed
Zabielski, R. (1994). Function of exocrine pancreas in growing calves. In The Developing of Digestive and Metabolic Processes in New Born and Growing Ruminants, Proceedings of Satellite Symposium to VIII ISRP, pp. 21–28 [Barej, W., Zabielski, R. and Ostaszewski, P., editors]. Warsaw, Poland: Fundacja “Rozwój SGGW”:.Google Scholar
Zabielski, R., Kato, S., Pierzynowski, S. G., Mineo, H., Podgurniak, P. & Barej, W. (1992 a) Effects of intraduodenal HC1 and soybean extract on pancreatic juice secretion during atropinization and cold vagal blockade in calves. Experimental Physiology 77, 807–817.CrossRefGoogle Scholar
Zabielski, R., Onaga, T., Mineo, H. & Kato, S. (1993) Periodic fluctuations in pancreatic secretion and duodenal motility investigated in neonatal calves. Experimental Physiology 78, 675–684.CrossRefGoogle ScholarPubMed
Zabielski, R., Pierzynowski, S. G., Podgurniak, P. & Barej, W. (1992 b) Effect of secretin and cholecystokinin octapeptide (CCK8) on exocrine pancreas during cold vagal blockade in calves. Journal of Animal Physiology and Animal Nutrition 67, 173–180.CrossRefGoogle Scholar
Zabielski, R., Terui, Y., Onaga, T., Mineo, H. & Kato, S. (1994) Plasma secretin fluctuates in phase with pancreatic periodic secretion and duodenal migrating myoelectric complex in calves. Research in Veterinary Science 56, 332–337.CrossRefGoogle ScholarPubMed