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Improvement of the probiotic effect of micro-organisms by their combination with maltodextrins, fructo-oligosaccharides and polyunsaturated fatty acids

Published online by Cambridge University Press:  09 March 2007

A. Bomba ,
R. Nemcová ,
S. Gancarcíková ,
R. Herich ,
P. Guba  and
D. Mudronová
A. Bomba*
Affiliation:
Research Institute of Veterinary Medicine, Hlinkova 1/A, 040 01, Slovak Republic
R. Nemcová
Affiliation:
Research Institute of Veterinary Medicine, Hlinkova 1/A, 040 01, Slovak Republic
S. Gancarcíková
Affiliation:
Research Institute of Veterinary Medicine, Hlinkova 1/A, 040 01, Slovak Republic
R. Herich
Affiliation:
University of Veterinary Medicine, Komenského 73 040 01, Košice, Slovak Republic
P. Guba
Affiliation:
Research Institute of Veterinary Medicine, Hlinkova 1/A, 040 01, Slovak Republic
D. Mudronová
Affiliation:
Research Institute of Veterinary Medicine, Hlinkova 1/A, 040 01, Slovak Republic
*
*Corresponding author: Dr A. Bomba, fax +421 55 63 318 53, email [email protected]
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Abstract

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Probiotics could represent an effective alternative to the use of synthetic substances in nutrition and medicine. The data concerning the efficacy of probiotics are often contradictory. This paper focuses on the enhancement of the efficacy of probiotics by their combination with synergistically acting components of natural origin. Maltodextrins can be obtained by enzymatic hydrolysis of starch and are suitable for consumption. Administration of Lactobacillus paracasei together with maltodextrin decreased the number of Escherichia coli colonising the jejunal mucosa of gnotobiotic piglets by 1 logarithm compared to the control group. Fructo-oligosaccharides (FOS) are naturally occurring oligosaccharides, mainly of plant origin. L. paracasei administered in combination with FOS significantly increased counts of Lactobacillus spp., Bifidobacterium spp., total anaerobes and total aerobes compared to the control group as well as the L. paracasei group. It also significantly decreased Clostridium and Enterobacterium counts in the faeces of the weanling piglets compared with the control group. Dietary lipids influence the gastrointestinal microbiota and specifically the population of lactic acid bacteria. In gnotobiotic piglets the oral administration of an oil containing polyunsaturated fatty acids (PUFA) significantly increased the number of L. paracasei adhering to jejunal mucosa compared to the control group. Our results showed that maltodextrin KMS X-70 and PUFA can be used to enhance the effect of probiotic micro-organisms in the small intestine, and similarly FOS enhance the effect of probiotic micro-organisms in the large intestine.

Keywords

ProbioticsMaltodextrinFructo-oligosaccharidesPolyunsaturated fatty acids
Type
Research Article
Information
British Journal of Nutrition , Volume 88 , Issue S1 , September 2002 , pp. S95 - S99
Copyright
Copyright © The Nutrition Society 2002

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