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Functional foods: psychological and behavioural functions

Published online by Cambridge University Press:  09 March 2007

Louise Dye*
Affiliation:
School of Psychology, University of Leeds, Leeds LS2 9JT, UK
John Blundell
Affiliation:
School of Psychology, University of Leeds, Leeds LS2 9JT, UK
*
*Corresponding author: Dr. L. Dye, fax +44 113 233 5749, email [email protected]
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Abstract

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It is easier to demonstrate the consistent effects of foods on satiety than on cognitive performance. This is understandable since the satiety system incorporates physiological signalling systems that mediate the effects of foods on function. Specific manipulations of proteins, carbohydrates and fats have the potential to act as functional foods for appetite control. Because of the importance of the optimal functioning of cognitions for survival, these functions are quite strongly protected against short-term dietary and physiological perturbances. Therefore, food manipulations may be better detected through the degree of effort exerted to maintain performance rather than via changes in the actual performance itself. This procedure has not been widely used hitherto. The concept of biomarkers may have to be interpreted differently from research on physiological systems or clinical endpoints. For satiety, adjustments in the profile of hunger could serve as a biomarker or surrogate endpoint. For cognitions, correlated physiological variables may be more difficult to measure than the functional endpoint itself. Changes related to unitary functions (such as tracking) could serve as biomarkers for more complex, integrated skills (such as car driving). Since food manipulations may affect multiple functions, the challenge is to design foods with good satiety control that do not impair mental performance; or alternatively to engineer foods that optimise cognitive performance without compromising satiety. This rapidly developing field has great potential for close collaboration between academia and industry in the production of commercially successful products that show clear improvements in human functioning with the capacity to protect against disease or impairment.

Type
Research Article
Copyright
Copyright © The Nutrition Society 2002

References

Astrup, A & Flatt, JP (1996) Metabolic determinants of body weight regulation. In Regulation of Body Weight: Biological and Behavioral Mechanisms, pp. 193210 [Bouchard, C and Bray, GA, editors]. Chichester: John Wiley.Google Scholar
Bellisle, F, Blundell, JE, Dye, L, Fantino, M, Fern, E, Fletcher, RJ, lambert, J, Roberfroid, M, Specter, S, Westenhöfer, J & Westerterp-plantenga, MS (1998) Functional food science and behaviour and psychological functions. British Journal Nutrition 80, S173S193.CrossRefGoogle ScholarPubMed
Benton, D (1995) Do low cholesterol levels slow mental processing? Psychosomatic Medicine 57, 5056.CrossRefGoogle ScholarPubMed
Benton, D & Donohoe, RT (1999) The effects of nutrients mood. Public Health Nutrition 2, 403409.CrossRefGoogle ScholarPubMed
Benton, D, Owens, D & Parker, P (1994) Blood glucose memory and attention. Neuropsychologia 115, 129.Google Scholar
Blundell, JE (1991) Pharmacological approaches to appetite suppression. Trends in Pharmacological Sciences 12, 147157.CrossRefGoogle ScholarPubMed
Blundell, JE, Burley, VJ & Peters, JC (1991) Dietary fat and human appetite: effects of non-absorbable fat on energy and nutrient intakes. In Obesity: Dietary Factors and Control, pp. 313 [Romsos, DR, editor]. Tokyo: Japan Science Society Press.Google Scholar
Blundell, JE & Cooling, J (2000) Routes to obesity: phenotypes, food choices and activity. British Journal of Nutrition 83, S33S38.CrossRefGoogle ScholarPubMed
Blundell, JE, Cotton, JR, Delargy, H, Green, S, Greenough, A, King, NA & Lawton, CL (1995) The fat paradox: fat-induced satiety signals versus high fat overconsumption. International Journal of Obesity 19, 832835.Google ScholarPubMed
Blundell, JE & Hill, AJ (1986) Influence of tryptophan on appetite and food selection in man. In Amino Acids in Health and Disease: New Perspectives, pp. 114 [Kaufman, S, Fernstrom, J, Roth, R and Woo, S, editors]. UCLA Symposia on Molecular and Cellular Biology, New Series vol. 55. New York: Alan Liss, Inc.Google Scholar
Blundell, JE & Hill, AJ (1987) Nutrition, serotonin and appetite: case study in the evolution of a scientific idea. Appetite 8, 183194.CrossRefGoogle ScholarPubMed
Blundell, JE, Lawton, CL, Cotton, JR & Macdiarmid, JI (1996) Control of human appetite: implications for the intake of dietary fat. Annual Review of Nutrition 16, 285319.CrossRefGoogle ScholarPubMed
Blundell, JE & Macdiarmid, JI (1997) Passive overconsumption fat intake and short-term energy balance. Annals of the New York Academy of Science 827, 392407.CrossRefGoogle ScholarPubMed
Blundell, JE & Naslund, E (1999) Glucagon-like peptide-1, satiety and appetite control (invited commentary). British Journal Nutrition 81, 259260.CrossRefGoogle Scholar
Blundell, JE & Rogers, PJ (1991 a) Satiating power of food. In Encyclopedia of Human Biology, vol. 6, pp. 723733. New York: Academic Press, Inc.Google Scholar
Blundell, JE & Rogers, PJ (1991 b) Hunger, hedonics, and the control of satiation and satiety. In Chemical Senses, pp. 127148 [Friedman, MTordoff, MG and Kare, M editors]. Appetite and Nutrition, vol. 4. New York: Marcel Dekker, Inc.Google Scholar
Blundell, JE, Rogers, PJ & Hill, AJ (1988) Uncoupling sweetness and calories: methodological aspects of laboratory studies Appetite control. Appetite 11, 5461.CrossRefGoogle ScholarPubMed
Booth, DA (1972) Postabsorptively induced suppression of appetite and the energostatic control of feeding. Physiology and Behavior 9, 199202.CrossRefGoogle ScholarPubMed
Booth, DA, Chase, A & Campbell, AT (1970) Relative effectiveness of protein in the late stages of appetite suppression in man. Physiology and Behavior 5, 12991302.CrossRefGoogle ScholarPubMed
Booth, DA, Mather, P & Fuller, J (1982) Starch content of ordinary foods associatively conditions human appetite and satiation indexed by intake and eating pleasantness of starch-paired flavours. Appetite 3, 163184.CrossRefGoogle ScholarPubMed
Burns, AA, Livingstone, MBE, Welch, RW, Dunne, A, Reid, CA & Rowland, IR (2001) The effects of yoghurt containing a novel fat emulsion on energy and macronutrient intakes in non-over-weight, overweight and obese subjects. International Journal of Obesity 25, 14871496.CrossRefGoogle ScholarPubMed
Burns, AA, Livingstone, MBE, Welch, RW, Dunne, A, Robson, PJ, Lindmark, L, Reid, CA, Mullaney, U & Rowland, IR (2000) Short-term effects of yoghurt containing a novel fat emulsion on energy and macronutrient intakes in non-obese subjects. International Journal of Obesity and Related Metabolic Disorders 24, 14101425.CrossRefGoogle ScholarPubMed
Butler, RN, Davies, M, Gehling, NJ & Grant, AK (1981) The effect of preloads of amino acid on short-term satiety. American Journal of Clinical Nutrition 34, 20452047.CrossRefGoogle Scholar
Campfield, LA & Smith, FJ (1986) Functional coupling between transient declines in blood glucose and feeding behaviour: temporal relationships. Brain Research Bulletin 17, 427433.CrossRefGoogle ScholarPubMed
Carlson, NR (1991) Physiology of Behaviour, 5th ed, p. 411. Boston, MA: Allyn & Bacon.Google Scholar
Cockle, SM, Haller, J, Kimber, S, Dawe, RA & Hindmarch, I (2000) The influence of multivitamins on cognitive function and mood in the elderly. Aging & Men's Health 4, 339353.CrossRefGoogle Scholar
Cordain, L, Brand Miller, J, Boyd Eaton, S, Mann, N, Holt, SHA & Speth, JD (2000) Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets. American Journal of Clinical Nutrition 71, 682692.CrossRefGoogle ScholarPubMed
Cotton, JR, Weststrate, JA & Blundell, JE (1996) Replacement of dietary fat with sucrose polyester: effects on energy intake and appetite control in nonobese males. American Journal of Clinical Nutrition 63, 891896.CrossRefGoogle ScholarPubMed
Crombie, N & Kirk, TR (1999) Prevention of weight gain and blood cholesterol reduction after consumption of a high carbohydrate food in men. International Journal of Obesity 23, Suppl. 5, 657.Google Scholar
Cunliffe, A, Obeid, OA & Powell-tuck, J (1997) Post-prandial changes in measures of fatigue: effect of a mixed or a pure carbohydrate or pure fat meal. European Journal of Clinical Nutrition 51, 831838.CrossRefGoogle ScholarPubMed
Cunliffe, A, Obeid, OA & Powell-tuck, J (1998) A placebo controlled investigation of the effects of tryptophan or placebo on subjective and objective measures of fatigue. European Journal of Clinical Nutrition 52, 831838.CrossRefGoogle ScholarPubMed
De graaf, C, de long, LS & Lambers, AC (1999) Palatability affects satiation but not satiety. Physiology and Behaviour 66, 681689.CrossRefGoogle Scholar
De graaf, C, Hulshof, T, Weststrate, JA & Hautvast, JG (1996) Nonabsorbable fat (sucrose polyester) and the regulation of energy intake and body weight. American Journal of Physiology 270, R1386–R1393.Google ScholarPubMed
Deijen, JB, Heemstra, ML & Orlebeke, JF (1989) Dietary effects on mood and performance. Journal of Psychiatric Research 23, 275283.CrossRefGoogle ScholarPubMed
Deijen, JB, Wientjes, CJE, Vullinghs, HFM, Cloin, PA & Langefeld, JJ (1999) Tyrosine improves cognitive performance and reduces blood pressure in cadets after one week of a combat training course. Brain Research Bulletin 48, 203209.CrossRefGoogle ScholarPubMed
Dickie, NH & Bender, AE (1982) Breakfast and performance in schoolchildren. British Journal of Nutrition 48, 483496.CrossRefGoogle Scholar
Fischer, K, Colombani, PC, Langhans, W & Wenk, C (2001) Cognitive performance and its relation to postprandial metabolic changes after different macronutrient ingestion in the morning. British Journal of Nutrition 85, 393405.CrossRefGoogle ScholarPubMed
Friedman, MI (1991) Metabolic control of calorie intake. In Chemical Senses, pp. 1938 [MI Friedman, MG Tordoff and MR Kare, editors]. Appetite and Nutrition, vol. 4. New York: Marcel Dekker, Inc.Google Scholar
Fryer, JH, Moore, NS, Williams, HH & Young, CM (1955) A study of the interrelationships of the energy-yielding nutrients, blood glucose levels and subjective appetite in man. Journal of Laboratory and Clinical Medicine 45, 684696.Google ScholarPubMed
Gale, CR, Martyn, CN & Cooper, C (1996) Cognitive impairment and mortality in a cohort of elderly people. British Medical Journal 312, 608611.CrossRefGoogle Scholar
Green, MW & Rogers, PJ (1995) Impaired cognitive functioning during spontaneous dieting. Psychological Medicine 25, 10031010.CrossRefGoogle ScholarPubMed
Green, MW, Rogers, PJ, Elliman, NA & Gatenby, SJ (1994 b) Impairment of cognitive function associated with dieting and high levels of dietary restraint. Physiology and Behavior 55, 447452.CrossRefGoogle Scholar
Green, SM, Burley, VJ & Blundell, JE (1994 a) Effect of fat- and sucrose-containing foods on the size of eating episodes and energy intake in lean males: potential for causing overconsumption. European Journal of Clinical Nutrition 48, 547555.Google ScholarPubMed
Green, SM, Delargy, HJ, Joanes, D & Blundell, JE (1997) A satiety quotient: a formulation to assess the satiating effect of food. Appetite 29, 291304.CrossRefGoogle ScholarPubMed
Greenough, A, Cole, G, Lewis, J, Lockton, A & Blundell, J (1998) Untangling the effects of hunger, anxiety, and nausea on energy intake during intravenous cholecystokinin octapeptide (CCK-8) infusion. Physiology and Behaviour 65, 303310.CrossRefGoogle ScholarPubMed
Greenwood, CE & Winocur, G (1997) An investigation of glucose effects on learning and memory impairments induced by high fat diets and environmental factors. Brain and Cognition 35, 415418.Google Scholar
Hassmen, P, Blomstrand, E, Ekblom, B & Newsholme, EA (1994) Branched-chain amino acid supplementation during 30-km competitive run: mood and cognitive performance. Nutrition 10, 405410.Google ScholarPubMed
Heaton, KW (1981) Dietary fibre and energy intake. In Regulators of Intestinal Absorption in Obesity, Diabetes and Nutrition, pp. 283294 [Berchtold, P, Cairella, A, Jacobelli, A and Silano, V, editors]. Rome: Societa Editriee Universo.Google Scholar
Hill, AJ & Blundell, JE (1986) Macronutrients and satiety: the effects of a high-protein or high-carbohydrate meal on subjective motivation to eat and food preferences. Nutrition and Behaviour 3, 133144.Google Scholar
Hill, AJ & Blundell, JE (1988) Role of amino acids in appetite control in man. In Amino Acid Availability and Brain Function in Health and Disease, pp. 239248 [Huether, G, editor]. Berlin: Springer-Verlag.CrossRefGoogle Scholar
Hill, AJ & Blundell, JE (1990) Sensitivity of the appetite control system in obese subjects to nutritional and serotoninergic challenges. International Journal of Obesity 14, 219233.Google ScholarPubMed
Hill, AJ, Magson, LD & Blundell, JE (1984) Hunger and palatability: tracking ratings of subjective experience before, during and after the consumption of preferred and less preferred food. Appetite 5, 361371.CrossRefGoogle ScholarPubMed
Hill, JO, Seagle, HM, Johnson, SL, Smith, S, Reed, GW, Tran, ZV, Cooper, D, Stone, M & Peters, JC (1998) Effects of 14 d of covert substitution of Olestra for conventional fat on spontaneous food intake. American Journal of Clinical Nutrition 67, 11781185.CrossRefGoogle ScholarPubMed
Hockey, GRJ (1997) Compensatory control in the regulation of human performance under stress and high workload: a cognitive energetical framework. Biological Psychology 45, 7393.CrossRefGoogle ScholarPubMed
Holt, SHA, Brand Miller, JC, Perocz, P & Farmakalidis, E (1995) A satiety index of common foods. European Journal of Clinical Nutrition 49, 675690.Google ScholarPubMed
Holt, SHA, Delargy, HJ, Lawton, CL & Blundell, JE (1999) The effects of high-carbohydrate vs high-fat breakfasts on feelings of fullness and alertness, and subsequent food intake. International Journal of Food Science and Nutrition 50, 1328.CrossRefGoogle ScholarPubMed
Horrocks, LA & Yeo, YK (1999) Health benefits of docosahexaenoic acid (DHA). Pharmacological Research 40, 211225.CrossRefGoogle ScholarPubMed
Johnson, J & Vickers, Z (1992) Factors influencing sensoryspecific satiety. Appetite 19, 1531.CrossRefGoogle ScholarPubMed
Kalmijn, S, Feskens, EJM, Launer, LJ & Kromhout, D (1997) Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. American Journal of Epidemiology 145, 3341.CrossRefGoogle ScholarPubMed
Kanarek, RB & Swinney, D (1990) Effects of food snacks on cognitive performance in male college students. Appetite 14, 1527.CrossRefGoogle ScholarPubMed
Kaplan, RJ, Greenwood, CE, Winocur, G & Wolever, TMS (2000) Cognitive performance is associated with glucose regulation in healthy elderly persons and can be enhanced with glucose and dietary carbohydrates. American Journal of Clinical Nutrition 72, 825836.CrossRefGoogle ScholarPubMed
Kaplan, RJ, Greenwood, CE, Winocur, G & Wolever, TMS (2001) Dietary protein, carbohydrate, and fat enhance memory performance in the healthy elderly. American Journal of Clinical Nutrition 74, 687693.CrossRefGoogle ScholarPubMed
Kelly, TH, Foltin, RW, Rolls, BJ & Fischman, MW (1994) Effect of meal macronutrient and energy content on human performance. Appetite 23, 97111.CrossRefGoogle ScholarPubMed
Kirk, TR, Burkill, S & Cursiter, MC (1997) Dietary fat reduction achieved by increasing consumption of a starchy food — an intervention study. European Journal of Clinical Nutrition 51, 455461.CrossRefGoogle ScholarPubMed
Kissileff, HR (1984) Satiating efficiency and a strategy for conducting food loading experiments. Neurological Biobehavioral Reviews 8, 129135.CrossRefGoogle Scholar
Klassen, T, Riedel, WJ, Deutz, NEP, van someren, A & van praag, HM (1999) Specificity of the tryptophan depletion method. Psychopharmacology 141, 279286.CrossRefGoogle Scholar
Lang, V, Bellisle, F, Oppert, J-M, Craplet, C, Bornet, FRJ, Slama, G & Guy-grand, B (1998) Satiating effect of proteins in healthy subjects: a comparison of egg albumin, casein, gelatin, soy protein, pea protein, and wheat glutin. American Journal of Clinical Nutrition 67, 11071204.CrossRefGoogle Scholar
Lawton, CL, Burley, VJ, Wales, JK & Blundell, JE (1993) Dietary fat and appetite control in obese subjects: weak effects on satiation and satiety. International Journal of Obesity 17, 409416.Google Scholar
Lawton, CL, Delargy, HJ, Brockman, J, Smith, FC & Blundell, JE (2000) The degree of saturation of fatty acids influences postingestive satiety. British Journal of Nutrition 83, 473482.CrossRefGoogle Scholar
Lawton, CL, Delargy, HJ, Smith, FC, Hamilton, V & Blundell, JE (1998) A medium-term intervention study on the impact of high- and low-fat snacks varying in sweetness and fat content: large shifts in daily fat intake but good compensation for daily energy intake. British Journal of Nutrition 80, 149161.CrossRefGoogle ScholarPubMed
Lenoury, JC, Cooling, J & Blundell, JE (2000) Different profiles of appetite and sleeping in high-fat and low-fat (behavioural) phenotypes. Appetite 35, 202.Google Scholar
Lethem, R & Orrell, M (1997) Antioxidants and dementia. Lancet 349, 11891190.CrossRefGoogle ScholarPubMed
Lieberman, HR, Corkin, S, Spring, BJ, Gowden, JH & Wurtman, RJ (1983) Mood, performance and pain sensitivity: changes induced by food constituents. Journal of Psychiatric Research 17, 135145.CrossRefGoogle Scholar
Lloyd, HM, Green, MW & Rogers, PJ (1994) Mood and cognitive performance effects of isocaloric lunches differing in fat and carbohydrate content. Physiology and Behavior 56, 5157.CrossRefGoogle ScholarPubMed
Lloyd, HM, Rogers, PJ, Hedderley, DI & Walker, AF (1996) Acute effects on mood and cognitive performance of breakfasts differing in fat and carbohydrate content. Appetite 27, 151164.CrossRefGoogle ScholarPubMed
Lluch, A, Dye, L & Blundell, JE (2000) Effects of nutrient manipulations on motivation to eat and performance in high fat and low fat phenotypes. Appetite 35, 202.Google Scholar
Macdiarmid, JI, Cade, JE & Blundell, JE (1996) High and low fat consumers, their macronutrient intake and body mass index: further analysis of the National Diet and Nutrition Survey of British Adults. European Journal of Clinical Nutrition 50, 505512.Google ScholarPubMed
Macdiarmid, JI & Hetherington, MM (1995) Mood modulation by food: an exploration of affect and cravings in 'chocolate addicts'. British Journal of Clinical Psychiatry 34, 129138.CrossRefGoogle ScholarPubMed
Markus, CR (1999) Relations between stress, food and mood: a role for brain serotonin. PhD Thesis, University of Utrecht.CrossRefGoogle Scholar
Markus, CR, Panhuysen, G, Tuiten, A, Koppeschaar, H, Fekkes, D & Peters, ML (1998) Does carbohydrate-rich, protein-poor food prevent a deterioration of mood and cognitive performance of stress-prone subjects when subjected to a stressful task. Appetite 31, 4965.CrossRefGoogle ScholarPubMed
Martin, PY & Benton, D (1999) The influence of a glucose drink on a demanding working memory task. Physiology and Behavior 67, 6974.CrossRefGoogle ScholarPubMed
Mayer, J (1953) Gluostatic mechanism of the regulation of food intake. New England Journal of Medicine 249, 1316.CrossRefGoogle ScholarPubMed
Mayer, J (1955) Regulation of energy intake and body weight. Annals of the New York Academy of Science 63, 1543.CrossRefGoogle ScholarPubMed
Mei, N (1985) Intestinal chemosensitivity. Physiology Reviews 65, 211237.CrossRefGoogle ScholarPubMed
Mellinkoff, SM, Frankland, M, Boyle, D & Greipel, M (1956) Relationship between serum amino acid concentration and fluctuations in appetite. Journal of Applied Physiology 8, 535538.CrossRefGoogle ScholarPubMed
Miller, DL, Catellanos, VH, Shide, DJ, Peters, JC & Rolls, BJ (1998) Effects of fat-free potato chips with and without nutrition labels on fat and energy intakes. American Journal of Clinical Nutrition 68, 282290.CrossRefGoogle ScholarPubMed
Milton, K (2000) Hunter-gatherer diets— a different perspective. American Journal of Clinical Nutrition 71, 665667.CrossRefGoogle ScholarPubMed
Moser, L, Plum, H & Bückmann, M (1983) Der Einfluß von Dextrose auf die psychophysische Leistungsfähigkeit des Autofahrers. Aktuelle Ernährungsmedizin 7, 714.Google Scholar
Muldoon, MF, Ryan, CM, Matthews, KA & Manuck, SB (1997) Serum cholesterol and intellectual performance. Psychosomatic Medicine 59, 382387.CrossRefGoogle ScholarPubMed
Novin, D, Vanderweele, DA & Rezek, M (1973) Hepatic-portal 2-deoxy-D-glucose infusion causes eating: evidence for peripheral glucoreceptors. Science 181, 858860.CrossRefGoogle ScholarPubMed
Oomura, Y (1988) Chemical and neuronal control of feeding motivation. Physiology and Behaviour 44, 555560.CrossRefGoogle ScholarPubMed
Owens, DS & Benton, D (1994) The impact of raising blood glucose on reaction times. Neuropsychobiology 30, 106113.CrossRefGoogle ScholarPubMed
Parker, PY & Benton, D (1995) Blood-glucose levels selectively influence memory for word lists dichotically presented to the right ear. Neuropsychologia 33, 843854.CrossRefGoogle Scholar
Ramirez, I (1990) What do we mean when we say 'palatable food'? Appetite 14, 159161.CrossRefGoogle ScholarPubMed
Reid, M & Hammersley, R (1995) Effects of carbohydrate intake on subsequent food intake and mood state. Physiology and Behaviour 58, 421427.CrossRefGoogle ScholarPubMed
Riedel, WJ, Klassen, T, Deutz, NEP, van someren, A & van praag, HM (1999) Tryptophan depletion in normal volunteers produces selective impairment in memory consolidation. Psychopharmacology 141, 362369.CrossRefGoogle ScholarPubMed
Roethlisberger, FJ (1997) The Elusive Phenomena: An Autobiographical Account of My Work in the Field of Organized Behavior at the Harvard Business School, p. 47. Cambridge, MA: Division of Research, Graduate School of Business Administration, Harvard University Press.Google Scholar
Rogers, PJ (2001) A healthy body, a healthy mind: long term impact of diet on mood and cognitive function. Proceedings of the Nutrition Society 60, 135143.CrossRefGoogle Scholar
Rogers, PJ & Blundell, JE (1989) Separating the actions of sweetness and calories: effects of saccharin and carbohydrates on hunger and food intake in human subjects. Physiology and Behaviour 45, 10931099.CrossRefGoogle ScholarPubMed
Rogers, PJ, Burley, VJ, Alikhanizadeh, LA & Blundell, JE (1995) Postingestive inhibition of food intake by aspartame: importance of interval between aspartame administration and subsequent eating. Physiology and Behaviour 57, 489493.CrossRefGoogle ScholarPubMed
Rogers, PJ & Green, MW (1993) Dieting, dietary restraint and cognitive performance. British Journal of Clinical Psychiatry 32, 113116.CrossRefGoogle ScholarPubMed
Rogers, PJ, Keedwell, P & Blundell, JE (1991) Further analysis of the short-term inhibition of food intake in humans by the dipeptide L-aspartyl-L-phenylalanine methyl ester (aspartame). Physiology and Behaviour 49, 739743.CrossRefGoogle ScholarPubMed
Rogers, PJ, Pleming, HC & Blundell, JE (1990) Aspartame ingested without tasting inhibits hunger and food intake. Physiology and Behaviour 47, 12391243.CrossRefGoogle ScholarPubMed
Rogers, PJ & Schutz, HG (1992) Influence of palatability on subsequent hunger and food intake: a retrospective replication. Appetite 19, 155156.CrossRefGoogle ScholarPubMed
Rolls, BJ, Jacobs Laster, L & Summerfelt, A (1989) Hunger and food intake following consumption of low-calorie foods. Appetite 13, 115127.CrossRefGoogle ScholarPubMed
Rolls, BJ, Kim-harris, S, Fischman, MW, Foltin, RW, Moran, TH & Stoner, SA (1988) Food intake in dieters and nondieters after a liquid meal containing medium-chain triglycerides. American Journal of Clinical Nutrition 48, 6671.CrossRefGoogle ScholarPubMed
Rolls, BJ, Kim-harris, S, Fischman, MW, Foltin, RW, Moran, TH & Stoner, SA (1994) Satiety after preloads with different amounts of fat and carbohydrate: implication for obesity. American Journal of Clinical Nutrition 60, 476487.CrossRefGoogle ScholarPubMed
Smith, AP, Clark, R & Gallagher, J (1999) Breakfast cereal and caffeinated coffee: effects on working memory, attention, mood, and cardiovascular function. Physiology and Behaviour 67, 917.CrossRefGoogle ScholarPubMed
Smith, AP, Clark, RE, Nutt, DJ, Haller, JG, Hayward, S & Perry, K (2000) Vitamin C, mood and cognitive functioning in the elderly. Nutrition and Neuroscience 2, 249256.CrossRefGoogle Scholar
Smith, AP & Kendrick, AM (1992) Meals and performance. In Health and Performance, pp. 223 [Smith, AP and Jones, DM, editors]. Handbook of Human Performance, vol. 2. London: Academic Press.Google Scholar
Smith, AP, Kendrick, A, Maben, A & Salmon, J (1994 a) Effects of breakfast and caffeine on cognitive performance, mood and cardiovascular functioning. Appetite 22, 3955.CrossRefGoogle ScholarPubMed
Smith, AP, Kendrick, A, Maben, A & Salmon, J (1994 b) Effects of fat content, weight, and acceptability of the meal on postlunch changes in mood, performance, and cardiovascular function. Physiology and Behaviour 55, 417422.CrossRefGoogle ScholarPubMed
Smith, AP, Leekham, S, Ralph, A & Mcneill, G (1988) The influence of meal composition on post-lunch performance efficiency and mood. Appetite 10, 195203.CrossRefGoogle ScholarPubMed
Smith, AP, Maben, A & Brockman, P (1994 c) Effects of evening meals and caffeine on cognitive performance, mood and cardiovascular functioning. Appetite 22, 765.Google ScholarPubMed
Smith, AP & Miles, C (1986 a) Acute effects of meals, noise and nightwork. British Journal of Psychiatry 77, 377387.Google ScholarPubMed
Smith, AP & Miles, C (1986 b) Effects of lunch on selective and sustained attention. Neuropsychobiology 16, 117120.CrossRefGoogle ScholarPubMed
Smith, AP & Miles, C (1986 c) The effects of lunch on cognitive vigilance tasks. Ergonomics 29, 12511261.CrossRefGoogle ScholarPubMed
Smith, AP & Rich, N (1998) Effects of consumption of snacks on simulated driving. Perceptual and Motor Skills 87, 817818.CrossRefGoogle ScholarPubMed
Spring, B, Maller, O, Wurtman, J, Digman, L & Gozolino, L (1983) Effects of protein and carbohydrate meals on mood and performance: interactions with sex and age. Journal of Psychiatric Research 17, 155167.CrossRefGoogle Scholar
Strachan, MWJ, Deary, IJ, Ewing, FME & Frier, BM (1997) Is type II diabetes associated with an increased risk of cognitive dysfunction? A critical review of published studies. Diabetes Care 20, 438445.CrossRefGoogle ScholarPubMed
Stubbs, R (1996) Macronutrients effects on appetite. International Journal of Obesity 19, S11119.Google Scholar
Stubbs, RJ & Harbron, CG (1995) Isoenergetic substitution of MCT for LCT: effect on energy intake in ad libitum feeding men. International Journal of Obesity 19, Suppl. 2, 28.Google Scholar
Teff, KL, Young, SN & Blundell, JE (1989) The effect of protein or carbohydrate breakfasts on subsequent plasma amino acid levels, satiety and nutrient selection in normal males. Pharmacology, Biochemistry and Behaviour 34, 829837.CrossRefGoogle ScholarPubMed
Thompson, DA & Campbell, RG (1977) Hunger in humans induced by 2-deoxy-D-glucose: glucoprivic control of taste preference and food intake. Science 198, 10651068.CrossRefGoogle ScholarPubMed
Tournier, A & Louis-sylvestre, J (1991) Effect of the physical state of food on subsequent intake in human subjects. Appetite 16, 1724.CrossRefGoogle ScholarPubMed
Trigazis, L, Orttmann, A & Anderson, GH (1997) Effect of a cholecystokinin- A receptor blocker on protein-induced food intake suppression in rats. American Journal of Physiology 272, R1826–R1833.Google ScholarPubMed
Van itallie, TB (1990) The gluostatic theory 1953–1988: roots and branches. International Journal of Obesity 14, Suppl. 3, 110.Google ScholarPubMed
Wainwright, PE, Huang, Y-S, Bulman-fleming, B, Levesque, S & Mccutcheon, D (1994) The effects of dietary fatty acid composition combined with environmental enrichment on brain and behavior in mice. Behavioural Brain Research 60, 125136.CrossRefGoogle ScholarPubMed
Welch, I, Saunders, K & Read, NW (1985) Effect of ileal and intravenous infusions of fat emulsions on feeding and satiety in human volunteers. Gastro 89, 12931297.CrossRefGoogle ScholarPubMed
Wells, AS & Read, NW (1996) Influences of fat, energy and time of day on mood and performance. Physiology and Behaviour 59, 10691076.CrossRefGoogle ScholarPubMed
Wells, AS, Read, NW & Craig, A (1995) Influences of dietary and intraduodenal lipid on alertness, mood and sustained concentration. British Journal of Nutrition 74, 115123.CrossRefGoogle ScholarPubMed
Westerterp-plantenga, MS, Rolland, V, Wilson, SAJ & Westerterp, KR (1999) Satiety related to 24 h diet-induced thermogenesis during high protein/carbohydrate vs high fat diets measured in a respiration chamber. European Journal of Clinical Medicine 53, 495502.Google Scholar
Wing, RR, Vazquez, JA & Ryan, CM (1995) Cognitive effects of ketogenic weight reducing diets. International Journal of Obesity 19, 811816.Google ScholarPubMed
Wurtman, JJ, Brzezinski, A, Wurtman, RJ & Laferrere, B (1989) Effect of nutrient intake on premenstrual depression. American Journal of Obstetrics and Gynecology 161, 12281234.CrossRefGoogle ScholarPubMed
Wurtman, RJ (1982) Nutrients that modify brain function. Scientific American 243, 4251.Google Scholar
Wurtman, RJ, Hefti, F & Melamed, E (1981) Precursor control of neurotransmitter synthesis. Pharmacological Reviews 32, 315335.Google Scholar
Wurtman, RJ & Wurtman, JJ (1986) Carbohydrates and depression. Scientific American 260, 5057.Google Scholar
Yeomans, MR (1996) Palatability and the microstructure of eating in humans: the appetiser effect. Appetite 27, 119133.CrossRefGoogle Scholar
Yeomans, MR, Hails, NJ & Nesic, JS (1999) Alcohol and the appetiser effect. Behavioural Pharmacology 10, 151161.CrossRefGoogle Scholar