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From absorption and excretion of minerals...to the importance of bioavailability and adaptation

Published online by Cambridge University Press:  09 August 2018

Susan J. Fairweather-Tait
Susan J. Fairweather-Tait*
Affiliation:
Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA
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It was nearly 120 years ago that the physiologist Claude Bernard proposed that for an organism to function optimally the component cells must be surrounded by a medium of closely regulated composition (‘La fixité du milieu interne est la condition de la vie libre’). Homeostasis is the term used today to describe this phenomenon, being first coined by Walter B. Cannon in 1929 (Hardy, 1976). This is the underlying physiological principle that explains the relative chemical constancy of the body, including inorganic nutrients such as Fe.

Type
Research Article
Information
British Journal of Nutrition , Volume 78 , Supplement s2: A New Millenium of Nutrition Research: A Celebration of the Ninetieth Birthday of Dr Elsie Widdowson CH CBE FRS DSc, 21 October 1996 , November 1997 , pp. S95 - S100
Copyright
Copyright © The Authors 1997

References

Bothwell, T. H. (1995). Overview and mechanisms of iron regulation. Nutrition Reviews 53, 237–245.Google Scholar
British Nutrition Foundation (1995). Iron. Nutritional and Physiological Significance. Report of the British Nutrition Foundation’s Task Force. London: Chapman & Hall.Google Scholar
Cavell, P. A. & Widdowson, E. M. (1964). Intakes and excretions of iron, copper, and zinc in the neonatal period. Archives of Diseases in Childhood 39, 496–501.CrossRefGoogle ScholarPubMed
Cook, J. D. (1990). Adaptation in iron metabolism. American Journal of Clinical Nutrition 51, 301–308.Google Scholar
Cook, J. D., Dassenko, S. A. & Lynch, S. R. (1991). Assessment of the role of non-heme iron availability in iron balance. American Journal of Clinical Nutriton 54, 717–722.Google Scholar
Cook, J. D., Layrisse, M., Martinez-Torres, C., Walker, R., Monsen, E. & Finch, C. A. (1972). Food iron absorption measured by an extrinsic tag. Journal of Clinical Investigation 51, 805–815.CrossRefGoogle ScholarPubMed
Cook, J. D., Watson, S. S., Simpson, K. M., Lipshitz, D. A. & Skikne, B. S. (1984). The effect of high ascorbic acid supplementation on body iron stores. Blood 64, 721–726.Google Scholar
Davidsson, L., Kastenmayer, P., Yuen, M., Lonnerdal, B. & Hurrell, R. F. (1993). Influence of lactoferrin on iron absorption from human milk in infants. Pediatrie Research 35, 117–124.Google Scholar
Fairweather-Tait, S. J., Balmer, S. E., Scott, P. H. & Minski, M. J. (1987). Lactoferrin and iron absorption in newborn infants. Pediatrie Research 22, 651–654.Google Scholar
Fairweather-Tait, S. J., Swindell, T. E. & Wright, A. J. A. (1985). Further studies in rats on the influence of previous iron intake on the estimation of bioavailability of Fe. British Journal of Nutrition 54, 79–86.Google Scholar
Fairweather-Tait, S. J. & Wright, A. J. A. (1984). The influence of previous iron intake on the estimation of bioavailability of Fe from a test meal given to rats. British Journal of Nutrition 51, 185–191.Google Scholar
Finch, C. (1994). Regulators of iron balance in humans. Blood 84, 1697–1702.Google Scholar
Food and Agriculture Organization/World Health Organization (1988). Requirements of Vitamin A, Iron, Folate and Vitamin B12. Report of a Joint Expert Consultation. Food Nutrition Series no. 23. Rome: FAO.Google Scholar
Hallberg, L. & Bjorn-Rasmussen, E. (1972). Determination of iron absorption from whole diet. A new two-pool model using two radioiron isotopes given as haem and non-haem iron. Scandinavian Journal of Haematology 9, 193–197.Google Scholar
Hallberg, L., Rossander-Hulthén, L., Brune, M. & Gleerup, A. (1992). Bioavailability in man of iron in human milk and cow’s milk in relation to their calcium contents. Pediatrie Research 31, 524–527.Google Scholar
Hardy, R. N. (1976). Homeostasis. The Institute of Biology’s Studies in Biology no. 63. London: Edward Arnold.Google Scholar
Lonnerdal, B., Bell, J. G. & Keen, C. L. (1985). Copper absorption from human milk, cow’s milk and infant formulas using a suckling rat model. American Journal of Clinical Nutrition 42, 836–844.Google Scholar
McCance, R. A & Widdowson, E. M. (1937 a). Absorption and excretion of iron. Lancet ii, 680–684.Google Scholar
McCance, R. A. & Widdowson, E. M. (1937 b). The fate of the elements removed from the blood stream during the treatment of polycythaemia by acetyl phenylhydrazine. Quarterly Journal of Medicine 6, 277–286.Google Scholar
McCance, R. A & Widdowson, E. M. (1938). The absorption and excretion of iron following oral and intravenous administration. Journal of Physiology 93, 148–154.Google Scholar
McCance, R. A. & Widdowson, E. M. (1942). Mineral metabolism of healthy adults on white and brown bread dietaries. Journal of Physiology 101, 44–85.Google Scholar
Mason, K. E. (1979). A conspectus of research on copper metabolism and requirements of man. Journal of Nutrition 109, 1979–2066.Google Scholar
Michaelson, K. F., Samuelson, G., Graham, T. W. & Lonnerdal, B. (1994). Zinc intake, zinc status and growth in a longitudinal study of healthy Danish infants. Acta Paediatrica 83, 1115–1121.Google Scholar
Minihane, A. M., Fairweather-Tait, S. J. & Eagles, J. (1997). The short and long term effects of calcium supplements on iron nutrition – is there an adaptive response? In Proceedings of the Ninth International Symposium on Trace Elements in Man and Animals, pp. 38–40 [Fischer, P. W. F., L’Abbe, M. R., Cockell, K. A. and Gibson, R. S., editors]. Ottawa: NRC Research Press.Google Scholar
Moore, R. J. & Veum, T. L. (1983). Adaptive increase in phytate digestibility by phosphorus-deprived rats and the relationship of intestinal phytase (EC 3.1.3.8) and alkaline phosphatase (EC 3.1.3.1) to phytate utilization. British Journal of Nutrition 49, 145–152.Google Scholar
Nahapetian, A. & Young, V. R. (1980). Metabolism of 14C-phytate in rats: effect of low and high dietary calcium intakes. Journal of Nutrition 110, 1458–1472.Google Scholar
Reinhold, J. G., Faraji, B., Abadi, P. & Ismail-Beigi, F. (1981). An extended study of the effect of Iranian village and urban flatbreads on the mineral balances of two men before and after supplementation with vitamin D. Ecology of Food and Nutrition 10, 169–177.Google Scholar
Sandberg, A.-S. & Ahdrinne, R. (1986). HPLC method for determination of inositol tri-, tetra-, penta-, and hexaphosphates in foods and intestinal contents. Journal of Food Science 51, 547–550.CrossRefGoogle Scholar
Sandström, B., Cederblad, A. & Lonnerdal, B. (1983). Zinc absorption from human, cow’s milk, and infant formula. American Journal of Diseases in Childhood 137, 726–729.Google Scholar
Sandström, B., Cederblad, A., Stenquist, B. & Andersson, H. (1990). Effect of inositol hexaphosphate on retention of zinc and calcium from the human colon. European Journal of Clinical Nutrition 44, 705–708.Google ScholarPubMed
Sandström, B., Fairweather-Tait, S., Hurrell, R. & van Dokkum, W. (1993). Methods for studying mineral and trace element absorption in humans using stable isotopes. Nutrition Research Reviews 6, 71–95.Google Scholar
Scientific Committee for Food (1993). Nutrient and Energy Intakes for the European Community. Luxembourg: Commission of the European Communities.Google Scholar
Tidehag, P., Hallmans, G., Wing, K., Sjöström, R., Ågren, G., Lundin, E. & Zhang, J.-X. (1996). A comparison of iron absorption from single meals and daily diets using radioFe (55Fe, 59Fe). British Journal of Nutrition 75, 281–289.Google Scholar
Walker, A. R. P., Fox, F. W. & Irving, J. T. (1948). Studies in human mineral metabolism. Biochemical Journal 42, 452–462.Google Scholar
Weaver, C. M., Heaney, R. P., Martin, B. R. & Fitzsimmons, M. L. (1991). Human calcium absorption from whole-wheat products. Journal of Nutrition 121, 1769–1775.Google Scholar
Widdowson, E. M. & McCance, R. A. (1937). The absorption and excretion of iron before, during and after a period of very high intake. Biochemical Journal 31, 2029–2034.Google Scholar