Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-03T08:42:54.496Z Has data issue: false hasContentIssue false

The effects of short periods of fasting on the absorption of heavy metals

Published online by Cambridge University Press:  09 March 2007

J. Quarterman
Affiliation:
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB2 9SB
Elaine Morrison
Affiliation:
Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB2 9SB
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Rats were deprived of food for periods of from 0 to 40 h and then given 203Pb, 203Hg. 59Fe, 64Cu. 64Zn or 45Ca by stomach tube. The absorption and retention of these metals in tissues was measured 1 h and 2 d after dosing.

2. After 16–24 h of food deprivation between two and ten times more metal was retained than after 0–12 h.

3. The effects of length of fast on metal uptake by the intestinal mucosa were greatest in the duodenum.

4. Lactale production by duodenal mucosa was halved after 12 h of food deprivation but galactose absorption was little changed after a 40 h fast.

Type
Papers of direct reference to Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1981

References

Beck, I. T. & Dinda, P. K. (1973). Can. J. Physiol. Pharmac. 51, 405.Google Scholar
Brown, H. O., Levine, M. L. & Lipkin, M. (1963). Am. J. Physiol. 205, 868.Google Scholar
Bruns, M. E., Fleischer, E. B. & Aviola, L. V. (1977). J. biol Chem. 252, 4145.CrossRefGoogle Scholar
Ekenved, G. & Arvidsson, B. (1976). Scand. J. Haematol. Supp. 28, 79.CrossRefGoogle Scholar
Fabry, P. (1962). Feeding pattern and nutritional adaptations. London: Butterworths.Google Scholar
Feher, J. J. & Wasserman, R. H. (1979). Am. J. Physiol. 236, E556.Google Scholar
Gruden, N. & Buben, M. (1979). Environ. Res. 18, 270.CrossRefGoogle Scholar
Lichtenberger, L., Welsh, J. D. & Johnson, L. R. (1976). Am. J. Dig. Dis. 21, 33.CrossRefGoogle Scholar
Linder, M. C., Dunn, V., Jones, I. D., Lin, S., Van Volkom, M. & Munro, H. N. (1975). Am. J. Physiol. 228, 196.Google Scholar
McManus, J. P. A. & Isselbacher, K. J. (1970). Gastroenterol. 59, 214.Google Scholar
Mead, J. F., Bennett, L. R., Decker, A. B. & Schoenberg, M. D. (1951). J. Nutr. 43, 477.CrossRefGoogle Scholar
Nellans, H. N. & Kimberg, D. V. (1979). Am. J. Physiol. 236, E473.Google Scholar
Newry, H., Sanford, P. A. & Smyth, D. H. (1970). J. Physiol. 208, 705.Google Scholar
Orr, J. M. & Benet, L. Z. (1975). Am. J. Dig. Dis. 20, 858.CrossRefGoogle Scholar
Quarterman, J., Morrison, J. N. & Humphries, W. R. (1976). Environ. Res. 12, 180.CrossRefGoogle Scholar
Rabinowitz, M. B., Kopple, J. D. & Wetherill, G. W. (1980). Am. J. clin. Nutr. 33, 1784.CrossRefGoogle Scholar
Richter, G. W. (1974). Am. J. Path. 74, 481.Google Scholar
Rudo, N. D., Rosenberg, J. H. & Wissler, R. W. (1976). Proc. Soc. exp. Biol. Med. 152, 277.CrossRefGoogle Scholar
Steiner, M. & Gray, S. J. (1959). Am. J. Physiol. 217, 747.Google Scholar
Taylor, D. M., Bligh, P. H. & Duggan, M. H. (1962). Biochem. J. 83, 25.CrossRefGoogle Scholar
Williams, R. B. & Mills, C. F. (1970). Br. J. Nutr. 24, 989.CrossRefGoogle Scholar