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Effects of protein and vitamin E on haemoglobin formation in rats

Published online by Cambridge University Press:  09 March 2007

J. Bunyan ,
J. Green  and
M. A. Cawthorne
J. Bunyan
Affiliation:
Beecham Research Laboratories, Vitamins Research Station, Walton Oaks, Tadworth, Surrey
J. Green
Affiliation:
Beecham Research Laboratories, Vitamins Research Station, Walton Oaks, Tadworth, Surrey
M. A. Cawthorne
Affiliation:
Beecham Research Laboratories, Vitamins Research Station, Walton Oaks, Tadworth, Surrey
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Abstract

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1. Young rats were given, for 9 weeks, vitamin E-deficient diets containing either 20% or 10% casein, with and without a dietary supplement of 350 ppm D-α-tocopheryl acetate. For the next 5 weeks the casein content of the low-protein diets was decreased to 7%.

2. The low-protein diets induced severe growth depression.

3. The dialuric acid-induced haemolysis test showed that the rats given the 20% casein vitamin E-deficient diet were depleted of vitamin E, but that the rate of depletion on the lowcasein diet was slower.

4. Haemoglobin levels were slightly decreased by the 10% casein diets after 9 weeks, but this difference was not found after 14 weeks, comparing 20% and 7% casein. Dietary vitamin E had no effect on haemoglobin levels or erythrocyte counts.

Type
Research Article
Information
British Journal of Nutrition , Volume 22 , Issue 4 , December 1968 , pp. 751 - 755
Copyright
Copyright © The Nutrition Society 1968

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