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The effect of the protein value of the diet on the neurological manifestations produced in rats by β,β-iminodipropionitrile

Published online by Cambridge University Press:  09 March 2007

Sabry Riad Morcos
Sabry Riad Morcos
Affiliation:
Human Nutrition Research Unit, National Institute for Medical Research, Mill Hill, London, NW 7
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Abstract

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1. The ‘landing’ and ‘swimming’ tests have been used to detect the onset of the neurological manifestations of toxicity of β,β-iminodipropionitrile (IDPN) in rats.

2. Rats on diets of net percentage of dietary protein calories (NDpCal%) of 10.1, 6.2 or 4.6 developed the syndrome later than those on diets of lower protein value.

3. L-Thyroxine did not prevent the development of the ECC-syndrome, but only delayed the onset of the action of IDPN.

Type
Research Article
Information
British Journal of Nutrition , Volume 21 , Issue 2 , May 1967 , pp. 269 - 274
Copyright
Copyright © The Nutrition Society 1967

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