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Effect of systemic infections on glycylglycine absorption rate from the human jejunum in vivo

Published online by Cambridge University Press:  09 March 2007

G. C. Cook
G. C. Cook
Affiliation:
Department of Medicine, The University of Zambia, PO Box RW 110, Lusaka, Zambia
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Abstract

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1. Using a double-lumen tube jejunal perfusion system, the rate of glycine absorption from a glycylglycine solution (50 mmol/l) was measured in three groups of Zambian African subjects: in fifteen subjects there was no evidence of an infection (normal group); in eleven there was acute bacterial pneumonia and five had a chronic systemic infection.

2. Differences between the mean absorption rates for the three groups were not significant.

3. Glycine absorption rate has been shown previously to be increased in subjects with acute bacterial pneumonia. The present result provides further evidence that glycine and glycylglycine use separate transfer mechanisms in man, and suggests that dipeptide absorption rate is influenced to a lesser extent than that for free amino acids by systemic stimuli.

Type
Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 32 , Issue 1 , July 1974 , pp. 163 - 167
Copyright
Copyright © The Nutrition Society 1974

References

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