Hostname: page-component-cd9895bd7-gxg78 Total loading time: 0 Render date: 2024-12-25T02:54:53.831Z Has data issue: false hasContentIssue false
  • English
  • Français

The effect of diets containing different proportions of butterfat and maize oil on plasma lipids and aortic atherosis in rabbits

Published online by Cambridge University Press:  09 March 2007

J. H. Moore
J. H. Moore
Affiliation:
Hannah Dairy Research Institute, Ayr
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Seven groups of male rabbits (thirteen to fifteen per group) were given ad lib. a diet consisting of 80 parts of a low-fat basal ration to which were added 20 parts of fat in the form of butterfat, maize oil or various mixtures of the two.

2. After 40 weeks, samples of blood were taken and the animals were killed. The concentrations of total cholesterol and phospholipid in the plasma and the fatty acid compositions of the plasma cholesteryl esters and phospholipids were determined. The degree of atheromatous degeneration was determined in the aortas.

3. Little aortic atherosis was observed in the rabbits given the diets containing 0, 10 and 12% butterfat, but as the butterfat content of the diet was increased above 12%, pronounced increases occurred in the extent of atheromatous degeneration of the aorta. The concentration of cholesterol in the plasma increased progressively as the butterfat content of the diet was increased and the maize oil content was decreased. There was an inverse curvilinear relationship between the degree of aortic atherosis and the phospholipid: cholesterol ratio in the plasma.

4. The concentration of linoleic acid in the plasma cholesteryl esters was inversely related to the concentration of cholesterol in the plasma, and the concentration of linoleic acid in the plasma phospholipids was inversely related to the concentration of phospholipids in the plasma. There was a positive linear relationship between the stearic: palmitic acid ratio and the linoleic: oleic acid ratio in the plasma phospholipids.

Type
Research Article
Information
British Journal of Nutrition , Volume 23 , Issue 1 , March 1969 , pp. 125 - 134
Copyright
Copyright © The Nutrition Society 1969

References

Collins, F. D. (1963). Biochem. J. 88, 319.CrossRefGoogle Scholar
Harris, P. M., Robinson, D. S. & Getz, G. (1960). Nature, Lond. 188, 742.CrossRefGoogle Scholar
Lewis, B. (1958). Lancet ii, 71.CrossRefGoogle Scholar
Moore, J. H. (1967). Br. J. Nutr. 21, 207.CrossRefGoogle Scholar
Moore, J. H. & Doran, B. M. (1962). Biochem. J. 84, 506.CrossRefGoogle Scholar
Moore, J. H. & Williams, D. L. (1963). Can. J. Biochem. Physiol. 41, 1821.CrossRefGoogle Scholar
Moore, J. H. & Williams, D. L. (1964 a). Br. J. Nutr. 18, 253.CrossRefGoogle Scholar
Moore, J. H. & Williams, D. L. (1964 b). Br. J. Nutr. 18, 431.CrossRefGoogle Scholar
Moore, J. H. & Williams, D. L. (1965 c). Biochem. biophys. Acta 84, 41.Google Scholar
Moore, J. H. & Williams, D. L. (1965 a). Br. J. Nutr. 19, 407.CrossRefGoogle Scholar
Moore, J. H. & Williams, D. L. (1965 b). Biochim. biophys. Acta 98, 137.CrossRefGoogle Scholar
Moore, J. H. & Williams, D. L. (1966). Br. J. Nutr. 20, 571.CrossRefGoogle Scholar
Moore, J. H., Williams, D. L. & Westgarth, D. R. (1965). Biochim. biophys. Acta 106, 145.CrossRefGoogle Scholar
Nelson, G. J. & Freeman, N. K. (1959). J. biol. Chem. 234, 1375.CrossRefGoogle Scholar
Swell, L., Schools, P. E. Jr & Treadwell, C. R. (1962 a). Proc. Soc. exp. Biol. Med. 109, 682.CrossRefGoogle Scholar
Swell, L., Schools, P. E. Jr & Treadwell, C. R. (1962 b). Proc. Soc. exp. Biol. Med. 111, 48.CrossRefGoogle Scholar
Van Deenen, L. L. M., Van Golde, L. M. G. & Demel, R. A. (1966). Biochem. J. 98, 178.Google Scholar
Wright, A. S., Pitt, G. A. J. & Morton, R. A. (1959). Lancet ii, 594.CrossRefGoogle Scholar