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The effect of amino acid imbalance on nitrogen retention (biological value) in rats

Published online by Cambridge University Press:  09 March 2007

B. O. Eggum ,
K. E. Bach Knudsen  and
Ingeborg Jacobsen
B. O. Eggum
Affiliation:
National Institute of Animal Science, Department of Animal Physiology and Chemistry, Rolighedsvej 25, DK-1958 Copenhagen, Denmark
K. E. Bach Knudsen
Affiliation:
National Institute of Animal Science, Department of Animal Physiology and Chemistry, Rolighedsvej 25, DK-1958 Copenhagen, Denmark
Ingeborg Jacobsen
Affiliation:
National Institute of Animal Science, Department of Animal Physiology and Chemistry, Rolighedsvej 25, DK-1958 Copenhagen, Denmark
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Abstract

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1. Three series of nitrogen balance experiments were performed with growing rats to test the effect of amino acid imbalance on protein utilization. In Expt 1 egg protein was fed as a basal diet and supplemented with one amino acid at a time in the amounts originally found in egg protein. In Expt 2 the procedure was repeated with a barley diet, and in Expt 3 egg and potato proteins were fed together in various combinations.

2. Doubling the single amino acids, especially arginine, in an egg-protein diet reduced biological value (BV) markedly. Also the branched-chain and the basic amino acids reduced BV significantly. In the barley-based diets negative effects were also observed when the concentration of the single amino acid was doubled. However, it was assumed that the observed deleterious effects of amino acid excess were partly due to an exaggerated lysine deficiency in the barley protein when non-limiting amino acids were added.

3. The results with various combinations of egg and potato proteins showed that as potato protein was increased true protein digestibility decreased linearly, whereas BV decreased Curvilinearly. Maximum protein utilization was obtained with egg protein alone.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 45 , Issue 1 , January 1981 , pp. 175 - 181
Copyright
Copyright © The Nutrition Society 1981

References

Association of Official Agricultural Chemists (1965). Official Methods of Analysis of the Association of Official Agricultural Chemists. Washington DC: Association of Official Agricultural Chemists.Google Scholar
Bender, A. E. (1961). Nat. Acad. Sci.-Nat. Rec. Counc. Washington DC Publ. 843, 407.Google Scholar
Brewer, M. F., Halvorson, J. D. & Clark, H. E. (1978). Am. J. clin. Nutr. 31, 786.CrossRefGoogle Scholar
Dunnett, C. W. (1964). Biometrics 20, 482.CrossRefGoogle Scholar
Eggum, B. O. (1968). Acta agric. scand. 18, 127.CrossRefGoogle Scholar
Eggum, B. O. (1973). Nutl Inst. anim. Sci. Copenhagen. Beretn. 406.Google Scholar
Harper, A. E. (1964). In Mammalian Protein Metabolism, Vol. 2 [Munro, H. N. and Allison, J. B., editors]. New York and London: Academic Press.Google Scholar
Harper, A. E. (1974). In Nutrients in Processed Foods, Proteins [White, P. L. and Fletcher, D. C., editors]. Acton, Massachussetts: Publishing Sciences Group. Inc.Google Scholar
Harper, A. E., Benevenga, N. J. & Wohlhueter, R. M. (1970). Physiol. Rev. 50, 428.CrossRefGoogle Scholar
Jones, J. D. (1962). Fedn Proc. Fedn Am. Socs exp. Biol. 21, 1.Google Scholar
Kadirval, R., Vohra, P. & Kratzer, F. H. (1974). J. Nutr. 104, 1127.CrossRefGoogle Scholar
Kamin, H. & Handler, P. (1952). Am. J. Physiol. 169, 305.CrossRefGoogle Scholar
Kofrànyi, E. (1972). Melsunger Med. Mitt. 46, 15.Google Scholar
Kofrànyi, E. & Jekat, F. (1964). Z. Physiol. Chem. 335, 166.CrossRefGoogle Scholar
Mason, V. C., Bech-Andersen, S. & Rudemo, M. (1980). Z. Tierphysiol. Tierernähr. Futtemittelk. 43, 146.CrossRefGoogle Scholar
Mitchell, H. H. & Beadles, J. R. (1950). J. Nutr. 40, 25.CrossRefGoogle Scholar
Waldroup, P. W., Mitchell, R. J., Payne, J. R. & Hazen, K. R. (1976). Poult. Sci. 55, 243.CrossRefGoogle Scholar
Woodham, A. A. & Deans, P. S. (1977). Br. J. Nutr. 37, 289.CrossRefGoogle Scholar