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Effect of alcohol on glucose, insulin, free fatty acid and triacylglycerol responses to a light meal in non-insulin-dependent diabetic subjects

Published online by Cambridge University Press:  17 March 2008

Christian Christiansen ,
Claus Thomsen ,
Ole Rasmussen ,
Catrine Hauerslev ,
Mette Balle ,
Carsten Hansen  and
Kjeld Hermansen
Christian Christiansen
Affiliation:
Institute of Clinical Experimental Research, Aarhus University Medical Department III, Aarhus University Hospital, Tage Hansensgade 2, DK-8000, Aarhus C, Denmark
Claus Thomsen
Affiliation:
Institute of Clinical Experimental Research, Aarhus University
Ole Rasmussen
Affiliation:
Medical Department III, Aarhus University Hospital, Tage Hansensgade 2, DK-8000, Aarhus C, Denmark
Catrine Hauerslev
Affiliation:
Medical Department III, Aarhus University Hospital, Tage Hansensgade 2, DK-8000, Aarhus C, Denmark
Mette Balle
Affiliation:
Medical Department III, Aarhus University Hospital, Tage Hansensgade 2, DK-8000, Aarhus C, Denmark
Carsten Hansen
Affiliation:
Department of Forensic Toxicology, Aarhus University, Denmark
Kjeld Hermansen
Affiliation:
Medical Department III, Aarhus University Hospital, Tage Hansensgade 2, DK-8000, Aarhus C, Denmark
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Abstract

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Alcohol accounts for 4-6% of the average energy intake in most Western countries. Alcohol-induced hypoglycaemia is a well-known and feared complication in insulin-dependent diabetic subjects, but little attention has been paid to the impact of alcohol on carbohydrate metabolism in non-insulin-dependent diabetes. The aim of the present study was to investigate in non-insulin-dependent diabetic subjects the acute metabolic effects of a moderate amount of alcohol taken with a light meal, conditions chosen to mimic an everyday situation. The patients received 500 ml non-alcoholic beer with an alcohol content (ml/l) of 0 (treatment A) and 54 (treatment B) together with a light meal, implying identity of the contents of ingredients except for alcohol. We found similar serum glucose, insulin, free fatty acid and triacylglycerol responses irrespective of addition of a modern amount of alcohol. In conclusion, a moderate amount of alcohol can be taken with a meal without eliciting hypoglycaemia in non-insulin-dependent diabetic subjects.

Keywords

Non-insulin-dependent diabetes mellitusBlood biochemistryAlcoholMan
Type
Research Article
Information
British Journal of Nutrition , Volume 71 , Issue 3 , March 1994 , pp. 449 - 454
Copyright
Copyright © The Nutrition Society 1994

References

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