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Correlation between the urinary excretion of acid-soluble peptides, fractional synthesis rate of whole body proteins, and plasma immunoreactive insulin-like growth factor-l/somatomedin C concentration in the rat

Published online by Cambridge University Press:  09 March 2007

Taek Jeong Nam ,
Tadashi Noguchi ,
Ryuhei Funabiki ,
Hisanori Kato ,
Yutaka Miura  and
Hiroshi Naito
Taek Jeong Nam
Affiliation:
Department of Agricultural Chemistry. Faculty of Agriculture, University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Tadashi Noguchi
Affiliation:
Department of Agricultural Chemistry. Faculty of Agriculture, University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Ryuhei Funabiki
Affiliation:
Department of Agricultural Chemistry, Faculty of Agriculture, Tokyo Noko University, Fuchu-shi 183, Japan
Hisanori Kato
Affiliation:
Department of Agricultural Chemistry. Faculty of Agriculture, University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Yutaka Miura
Affiliation:
Department of Agricultural Chemistry. Faculty of Agriculture, University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
Hiroshi Naito
Affiliation:
Department of Agricultural Chemistry. Faculty of Agriculture, University of Tokyo, Bunkyo-ku, Tokyo 113, Japan
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Abstract

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The relations between the urinary excretion of acid-soluble peptide (ASP)-form amino acids, the rate of whole body protein synthesis and plasma immunoreactive insulin-like growth factor-1/somatomedin C concentration were investigated in rats. The urinary ASP-form leucine plus valine excretion correlated well with the rate of whole body protein synthesis and with the plasma immunoreactive insulin-like growth factor-1 concentration. The results provide further evidence for the hypothesis that urinary excretion of ASP is an excellent index of the status of protein metabolism in animals.

Keywords

Insulin-like growth factor-1Protein synthesisAcid-soluble peptidesRat
Type
Protein Nutrition and Metabolism
Information
British Journal of Nutrition , Volume 63 , Issue 3 , May 1990 , pp. 515 - 520
Copyright
Copyright © The Nutrition Society 1990

References

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