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Changes in lysosomal hydrolase activity associated with malnutrition in young rats

Published online by Cambridge University Press:  24 July 2007

Anne Roobol  and
G. A. O Alleyne
Anne Roobol
Affiliation:
Tropical Metabolism Research Unit and Department of Medicine, University of the West Indies, Mona, Kingston 7, Jamaica
G. A. O Alleyne
Affiliation:
Tropical Metabolism Research Unit and Department of Medicine, University of the West Indies, Mona, Kingston 7, Jamaica
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Abstract

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1. Total lysosomal hydrolase activities were measured in liver, gastrocnemius muscle and plasma of malnourished and normal rats between 3 and 8 weeks of age.

2. Concurrently, the DNA and protein contents of the livers and muscles were determined.

3. Increased amounts of acid hydrolase activities were found to be associated with subnormal protein: DNA ratios in the tissues of malnourished rats.

4. It was concluded that lysosomal enzymes may be involved in protein catabolism during malnutrition.

Type
General Nutrition
Information
British Journal of Nutrition , Volume 32 , Issue 2 , September 1974 , pp. 189 - 197
Copyright
Copyright © The Nutrition Society 1974

References

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