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Carbohydrate bioavailability

Published online by Cambridge University Press:  08 March 2007

Klaus N. Englyst  and
Hans N. Englyst
Klaus N. Englyst*
Affiliation:
Englyst Carbohydrates, 2 Venture Road, Chilworth Science Park, Southampton, UK
Hans N. Englyst
Affiliation:
Englyst Carbohydrates, 2 Venture Road, Chilworth Science Park, Southampton, UK
*
*Corresponding author: Dr Klaus N. Englyst, fax +44 23 80 769654, email [email protected]
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Abstract

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There is consensus that carbohydrate foods, in the form of fruit, vegetables and whole-grain products, are beneficial to health. However, there are strong indications that highly processed, fibre-depleted, and consequently rapidly digestible, energy-dense carbohydrate food products can lead to over-consumption and obesity-related diseases. Greater attention needs to be given to carbohydrate bioavailability, which is determined by the chemical identity and physical form of food. The objective of the present concept article is to provide a rational basis for the nutritional characterisation of dietary carbohydrates. Based on the properties of carbohydrate foods identified to be of specific relevance to health, we propose a classification and measurement scheme that divides dietary carbohydrates into glycaemic carbohydrates (digested and absorbed in the small intestine) and non-glycaemic carbohydrates (enter the large intestine). The glycaemic carbohydrates are characterised by sugar type, and by the likely rate of digestion described by in vitro measurements for rapidly available glucose and slowly available glucose. The main type of non-glycaemic carbohydrates is the plant cell-wall NSP, which is a marker of the natural fibre-rich diet recognised as beneficial to health. Other non-glycaemic carbohydrates include resistant starch and the resistant short-chain carbohydrates (non-digestible oligosaccharides), which should be measured and researched in their own right. The proposed classification and measurement scheme is complementary to the dietary fibre and glycaemic index concepts in the promotion of healthy diets with low energy density required for combating obesity-related diseases.

Keywords

Carbohydrate classificationStarchNon-starch polysaccharidesGlycaemic indexDietary fibre
Type
Horizons in Nutritional Science
Information
British Journal of Nutrition , Volume 94 , Issue 1 , July 2005 , pp. 1 - 11
Copyright
Copyright © The Nutrition Society 2005

References

Birkett, A, Muir, A, Phillips, J, Jones, G & O'Dea, K (1996) Resistant starch lowers fecal concentrations of ammonia and phenols in humans. Am J Clin Nutr 63, 766–772.CrossRefGoogle ScholarPubMed
Bjorck, I & Liljeberg-Elmstahl, H (2003) The glycaemic index: importance of dietary fibre and other food properties. Proc Nutr Soc 62, 201–206.CrossRefGoogle ScholarPubMed
Brand-Miller, JC, Holt, SHA, Pawlak, DB & McMillan, J (2002) Glycemic index and obesity. Am J Clin Nutr 76, Suppl., 281S–285S.CrossRefGoogle ScholarPubMed
Burke, LM, Kiens, B & Ivy, JL (2004) Carbohydrates and fat for training and recovery. J Sports Sci 22, 15–30.CrossRefGoogle ScholarPubMed
Burn, J, Katheuser, A, Fodde, R, Coaker, J, Chapman, PD & Mathers, JC (1996) Intestinal tumours in the Apc 1638N mouse: aspirin not protective and resistant starch increases small bowel tumours. Eur J Hum Genet 4, Suppl. 1, 13.Google Scholar
Champ, M, Langkilde, AM, Brouns, F, Kettlitz, B & Bail-Collet, Y (2003) Advances in dietary fibre characterisation. 2. Consumption, chemistry, physiology and measurement of resistant starch; implications for health and food labelling. Nutr Res Rev 16, 143–161.CrossRefGoogle ScholarPubMed
Cherbut, C (1995) Role of gastrointestinal motility in the delay of absorption by dietary fibre. Eur J Clin Nutr 49, Suppl., S74–S80.Google ScholarPubMed
Collier, G, McLean, A & O'Dea, K (1984) Effect of co-ingestion of fat on the metabolic responses to rapidly absorbed carbohydrates. Diabetologia 26, 50–54.CrossRefGoogle ScholarPubMed
Colonna, P, LeLoup, V & Buleon, A (1992) Limiting factors of starch hydrolysis. Eur J Clin Nutr 46, Suppl. 2, S17–S32.Google ScholarPubMed
Cummings, JH (1993) The effect of dietary fiber on fecal weight and constipation. In CRC Handbook of Dietary Fiber in Human Nutrition, pp. 263–349[Spiller, GA, editor]. Boca Raton, FL: CRC Press.Google Scholar
Cummings, JH, Macfarlane, GT & Englyst, HN (2001) Digestion of prebiotics and fermentation by intestinal microflora. Am J Clin Nutr 73, 415–420.CrossRefGoogle Scholar
Daly, ME, Vale, C, Walker, M, Alberti, KGMM & Mathers, JC (1997) Dietary carbohydrates and insulin sensitivity: a review of the evidence and clinical implications. Am J Clin Nutr 66, 1072–1085.CrossRefGoogle ScholarPubMed
Daly, ME, Vale, C, Walker, M, Littlefield, A, Alberti, KGMM & Mathers, JC (1998) Acute effects on insulin sensitivity and diurnal metabolic profiles of high-sucrose compared with a high-starch diet. Am J Clin Nutr 67, 1186–1196.CrossRefGoogle ScholarPubMed
Daly, ME, Vale, C, Walker, M, Littlefield, A, Alberti, KGMM & Mathers, JC (2000) Acute fuel selection in response to high-sucrose and high-starch meals in healthy men. Am J Clin Nutr 71, 1516–1524.CrossRefGoogle ScholarPubMed
Englyst, HN & Cummings, JH (1985) Digestion of the polysaccharides of some cereal foods in the human small intestine. Am J Clin Nutr 42, 778–787.CrossRefGoogle ScholarPubMed
Englyst, HN & Cummings, JH (1986) Digestion of the carbohydrates of banana ( Musa paradisiaca sapientum ) in the human small intestine. Am J Clin Nutr 44, 42–50.CrossRefGoogle ScholarPubMed
Englyst, HN & Cummings, JH (1987) Digestion of the polysaccharides of potato in the small intestine of man. Am J Clin Nutr 45, 423–431.CrossRefGoogle ScholarPubMed
Englyst, HN, Bingham, SA, Runswick, SA, Collinson, E & Cummings, JH (1988) Dietary fibre (non-starch polysaccharides) in fruit, vegetables and nuts. J Hum Nutr Diet 1, 247–286.CrossRefGoogle Scholar
Englyst, HN, Bingham, SA, Runswick, SA, Collinson, E & Cummings, JH (1989) Dietary fibre (non-starch polysaccharides) in cereal products. J Hum Nutr Diet 2, 253–271.CrossRefGoogle Scholar
Englyst, HN, Kingman, SM & Cummings, JH (1992) Classification and measurement of nutritionally important starch fractions. Eur J Clin Nutr 46, Suppl., S33–S50.Google ScholarPubMed
Englyst, HN, Quigley, ME & Hudson, GJ (1994) Determination of dietary fiber as non-starch polysaccharides with gas–liquid chromatographic, high-performance liquid chromatographic or spectrophotometric measurement of constituent sugars. Analyst 119, 1497–1509.CrossRefGoogle ScholarPubMed
Englyst, HN, Quigley, ME & Hudson, GJ (2000) Dietary fibre analysis as non-starch polysaccharides. In Encyclopaedia of Analytical Chemistry, 3912–3929[Meyers, RA, editor]. Chichester: John Wiley & Sons.Google Scholar
Englyst, HN, Trowell, H, Southgate, DAT & Cummings, JH (1987) Dietary fiber and resistant starch. Am J Clin Nutr 46, 873–874.CrossRefGoogle ScholarPubMed
Englyst, HN, Veenstra, J & Hudson, GJ (1996) Measurement of rapidly available glucose (RAG) in plant foods: a potential in vitro predictor of the glycaemic response. Br J Nutr 75, 327–337.CrossRefGoogle Scholar
Englyst, HN, Wiggins, HS & Cummings, JH (1982) Determination of the non-starch polysaccharides in plant foods by gas–liquid chromatography of constituent sugars as alditol acetates. Analyst 107, 307–318.CrossRefGoogle ScholarPubMed
Englyst, KN & Englyst, HN (2004) Detecting nutritional starch fractions. In Starch in Food: Structure, Function and Applications, pp. 541–559[Eliasson, A-C, editor]. Cambridge, UK: Woodhead Publishing.CrossRefGoogle Scholar
Englyst, KN, Englyst, HN, Hudson, GJ, Cole, TJ & Cummings, JH (1999) Rapidly available glucose in foods. An in vitro measurement that reflects the glycemic response. Am J Clin Nutr 69, 448–454.CrossRefGoogle Scholar
Englyst, KN, Hudson, GJ & Englyst, HN (2000) Starch analysis in food. In Encyclopaedia of Analytical Chemistry, pp. 4246–4262[Meyers, RA, editor]. Chichester: John Wiley & Sons.Google Scholar
Englyst, KN, Vinoy, S, Englyst, HN & Lang, V (2003) Glycaemic index of cereal products explained by their content of rapidly and slowly available glucose. Br J Nutr 89, 329–339.CrossRefGoogle ScholarPubMed
Evans, RC, Fear, S, Ashby, D, Hackett, A, Williams, E, Van Der Vliet, M, Dunstan, FD & Rhodes, JM (2002) Diet and colorectal cancer: an investigation of the lectin/galactose hypothesis. Gastroenterology 122, 1784–1792.CrossRefGoogle ScholarPubMed
Flint, A, Moller, BK, Raben, A, Pedersen, D, Tetens, I, Holst, JJ & Astrup, A (2004) The use of glycaemic index tables to predict glycaemic index of composite breakfast meals. Br J Nutr 91, 979–989.CrossRefGoogle ScholarPubMed
Food and Agriculture Organization of the United Nations/World Health Organization Expert Consultation (1998) Carbohydrates in Human Nutrition. FAO Food and Nutrition Paper no. 66. Geneva: FAO/WHO.Google Scholar
Food and Drug Administration (2000) Letter regarding supplement health claim for dietary fiber with respect to colon cancer. Document no. 91N-0098. http://www.cfsan.fda.gov/~dms/ds-ltr8.htmlGoogle Scholar
Frayn, KN & Kingman, SM (1995) Dietary sugars and lipid metabolism in humans. Am J Clin Nutr 62, Suppl., 250S–261S.CrossRefGoogle ScholarPubMed
Frost, G, Leeds, A, Dore, J, Madeiros, S, Brading, S & Dornhorst, A (1999) Glycaemic index as a determinant of serum HDL-cholesterol concentration. Lancet 353, 1045–1048.CrossRefGoogle ScholarPubMed
Gallant, DJ, Bouchet, B, Buleon, A & Perez, S (1992) Physical characteristics of starch granules and susceptibility to enzymatic degradation. Eur J Clin Nutr 46, Suppl. 2, S3–S16.Google ScholarPubMed
Gannon, MC, Khan, MA & Nuttall, FQ (2001) Glucose appearance rate after the ingestion of galactose. Metabolism 50, 93–98.CrossRefGoogle ScholarPubMed
Goodlad, RA & Englyst, HN (2001) Redefining dietary fibre: potentially a recipe for disaster. Lancet 358, 1833–1834.CrossRefGoogle ScholarPubMed
Gudmand-Hoyer, E (1994) The clinical significance of disaccharide maldigestion. Am J Clin Nutr 59, Suppl., 735S–741S.CrossRefGoogle ScholarPubMed
Haber, GB, Heaton, KW, Murphy, D & Burroughs, LD (1977) Depletion and disruption of dietary fibre. Lancet ii, 679–682.CrossRefGoogle Scholar
Heaton, KW, Marcus, SN, Emmett, PM & Bolton, CH (1988) Particle size of wheat, maize, and oat test meals: effects on plasma glucose and insulin responses and on the rate of starch digestion in vitro. Am J Clin Nutr 47, 675–682.CrossRefGoogle ScholarPubMed
Jenkins, DJA, Kendall, CWC, Augustin, LSA, Franceschi, S, Hamidi, M, Marchie, A, Jenkins, DJA, Wolever, TMS & Taylor, RH (1981) Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 34, 362–366.CrossRefGoogle Scholar
Jenkins, DJA, Kendall, CWC, Augustin, LSA, Franceschi, S, Hamidi, M, Marchie, A, Jenkins, AL & Axelsen, M (2002) Glycemic index: overview of implications in health and disease. Am J Clin Nutr 76, Suppl., 266S–273S.CrossRefGoogle ScholarPubMed
Jeppesen, J, Schaaf, P, Jones, C, Zhou, MY, Chen, YDI & Reaven, GM (1997) Effects of low-fat, high-carbohydrate diets on risk factors for ischemic heart disease in postmenopausal women. Am J Clin Nutr 65, 1027–1033.CrossRefGoogle ScholarPubMed
Liu, S, Manson, JE, Stampfer, MJ, Hu, FB, Holmes, MD, Franz, M, Sampson, L, Hankinson, SE & Willett, WC (2001) Dietary glycemic load assessed by food frequency questionnaire in relation to plasma HDL-cholesterol and fasting triglycerides in postmenopausal women. Am J Clin Nutr 71, 1455–1461.CrossRefGoogle Scholar
Liu, S, Stampfer, MJ & Manson, JE (1998) A prospective study of glycemic load and risk of myocardial infarction in women. FASEB J 12, A260.Google Scholar
Livesey, G (2001) Tolerance of low digestible carbohydrates: a general review. Br J Nutr 85, Suppl., S7–S16.CrossRefGoogle Scholar
Ludwig, DS (2000) Dietary glycemic index and obesity. J Nutr 130, Suppl., 280S–283S.CrossRefGoogle ScholarPubMed
Mayes, PA (1993) Intermediary metabolism of fructose. Am J Clin Nutr 58, Suppl., 754S–765S.CrossRefGoogle ScholarPubMed
Meyers, KA, Kushi, LH, Jacobs, DR, Slavin, J, Sellers, TA & Folsom, AR (2000) Carbohydrates, dietary fiber and incidence of type 2 diabetes in older women. Am J Clin Nutr 71, 921–930.CrossRefGoogle Scholar
Nuttall, FQ, Khan, MA & Gannon, MC (2000) Peripheral glucose appearance rate following fructose ingestion in normal subjects. Metabolism 49, 1565–1571.CrossRefGoogle ScholarPubMed
Opperman, AM, Venter, CS, Oosthuizen, W, Thompson, RL & Vorster, HH (2004) Meta-analysis of the health effects of using the glycaemic index in meal planning. Br J Nutr 92, 367–381.CrossRefGoogle ScholarPubMed
Parks, EJ & Hellerstein, MK (2000) Carbohydrate-induced hypertriacylglycerolemia: historical perspective and review of biological mechanisms. Am J Clin Nutr 71, 412–433.CrossRefGoogle ScholarPubMed
Rayner, CK, Jones, KL, Samson, M & Horowitz, M (2001) Relationships of upper gastrointestinal motor and sensory function with glycemic control. Diabetes Care 24, 371–381.CrossRefGoogle ScholarPubMed
Robertson, MD, Livesey, G & Mathers, JC (2002) Quantitative kinetics of glucose appearance and disposal following a 13 C-labelled starch-rich meal: comparison of male and female subjects. Br J Nutr 87, 569–577.CrossRefGoogle Scholar
Salmeron, J, Manson, J, Stampfer, M, Colditz, G, Wing, A & Willett, W (1997) Dietary fiber, glycemic load, and risk of non insulin dependent diabetes mellitus in women. JAMA 277, 472–477.CrossRefGoogle ScholarPubMed
Seal, CJ, Daly, ME, Thomas, LC, Bal, W, Birkett, AM, Jeffcoat, R & Mathers, JC (2003) Postprandial carbohydrate metabolism in healthy subjects and those with type 2 diabetes fed starches with slow and rapid hydrolysis rates determined in vitro. Br J Nutr 90, 853–864.CrossRefGoogle ScholarPubMed
Silvester, KR, Englyst, HN & Cummings, JH (1995) Ileal recovery of starch from whole diets containing resistant starch measured in vitro and fermentation of ileal effluent. Am J Clin Nutr 62, 403–411.CrossRefGoogle ScholarPubMed
Spieth, LE, Harnish, JD, Lenders, CM, Raezer, LB, Pereira, MA, Hangen, J & Ludwig, DS (2000) A low glycemic index diet in the treatment of pediatric obesity. Arch Pediatr Adolesc Med 154, 947–951.CrossRefGoogle ScholarPubMed
Steer, T, Carpenter, H, Tuohy, K & Gibson, GR (2000) Perspectives on the role of the human gut microbiota and its modulation by pro- and prebiotics. Nutr Res Rev 13, 229–254.CrossRefGoogle ScholarPubMed
Thomsen, C, Rasmussen, OW, Chriastiansen, C, Andreasen, F, Poulsen, PL & Hermansen, K (1994) The glycaemic index of spaghetti and gastric emptying in non-insulin-dependent diabetic patients. Eur J Clin Nutr 48, 776–780.Google ScholarPubMed
Trowell, H (1972) Crude fibre, dietary fibre and atherosclerosis. Atherosclerosis 16, 138–140.CrossRefGoogle ScholarPubMed
Trowell, H (1985) Dietary fibre; a paradigm. In Dietary Fibre, Fibre-Depleted Foods and Disease, pp. 1–20[Trowell, HC, Burkitt, D and Heaton, KW, editors]. London: Academic Press.Google Scholar
Truswell, AS (1994) Food carbohydrates and plasma lipids – an update. Am J Clin Nutr 59, Suppl., S710–S718.CrossRefGoogle ScholarPubMed
UK Parliament Health Committee (2004) Health – Third Report, Session 2003–04. London: The Stationery Office, http://www.publications.parliament.uk/pa/cm200304/cmselect/cmhealth/23/2302.htmGoogle Scholar
Van Dam, RM, Visscher, AWJ, Feskens, EJM, Verhoef, P & Kromhout, D (2000) Dietary glycemic index in relation to metabolic risk factors and incidence of coronary heart disease: the Zutphen Elderly Study. Eur J Clin Nutr 54, 726–731.CrossRefGoogle ScholarPubMed
Van Loo, J, Cummings, J & Delzenne, N (1999) Functional food properties of non-digestible oligosaccharides: a consensus report from the ENDO project (DGXII AIRII-CT94-1095). Br J Nutr 81, 121–132.Google ScholarPubMed
Van Munster, IP, Tangerman, A & Nagengast, FM (1994) Effect of resistant starch on colonic fermentation, bile-acid metabolism, and mucosal proliferation. Dig Dis Sci 39, 834–842.CrossRefGoogle ScholarPubMed
Wasan, HS & Goodlad, RA (1996) Fibre-supplemented foods may damage your health. Lancet 348, 319–320.CrossRefGoogle ScholarPubMed
Westphal, SA, Gannon, MC & Nuttall, FQ (1990) Metabolic response to glucose ingested with various amounts of protein. Am J Clin Nutr 52, 267–272.CrossRefGoogle ScholarPubMed
Wolever, TMS (2003) Carbohydrate and the regulation of blood glucose and metabolism. Nutr Rev 61, Suppl., S40–S48.CrossRefGoogle ScholarPubMed
World Health Organization (2003) Diet, Nutrition and the Prevention of Chronic Disease. Technical Report Series no. 916 Geneva: WHO, http://www.who.int/hpr/NPH/docs/who_fao_expert_report.pdfGoogle Scholar
Young, GPMcIntyre, AAlbert, V, Folino, M, Muir, JG & Gibson, PR (1996) Wheat bran suppresses potato starch-potentiated colorectal tumorigenesis at the aberrant crypt stage in a rat model. Gastroenterology 110, 508–514.CrossRefGoogle ScholarPubMed