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Bioefficiency of different tocopherols in chicken as assessed by haemolysis test and microsomal pentane production

Published online by Cambridge University Press:  09 March 2007

Herbert Fuhrmann ,
Sukurani T. Balthazary  and
Hans-Peter Sallmann
Herbert Fuhrmann
Affiliation:
Department of Physiological Chemistry, Hanover Veterinary School, Buenteweg 17, 30 559 Hannover 71, Germany
Sukurani T. Balthazary
Affiliation:
Department of Physiological Chemistry, Hanover Veterinary School, Buenteweg 17, 30 559 Hannover 71, Germany
Hans-Peter Sallmann
Affiliation:
Department of Physiological Chemistry, Hanover Veterinary School, Buenteweg 17, 30 559 Hannover 71, Germany
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Abstract

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Bioefficiencies of α-, γ- and δ-tocopherol in comparison with all-rac-α-tocopherol were established in broiler chickens. For this, 1-d-old male broiler chickens received a diet deficient in vitamin E and supplemented with increasing doses of the corresponding tocopheryl acetates. After 2 and 3 weeks of feeding, the animals were killed to obtain blood and liver samples. The ex vivo tests used were detergent induced haemolysis and pentane production by liver microsomes. Bioefficiencies were calculated by comparison of the dose–response curves. It is concluded that haemolysis and pentane production are appropriate indicators of the bioefficiency of tocopherols in broiler chickens. The values obtained by both tests hardly differed and agree well with the figures previously obtained from rats and other species.

Keywords

BioefficiencyVitamin EPentaneHaemolysisChicken
Type
Research Article
Information
British Journal of Nutrition , Volume 71 , Issue 4 , April 1994 , pp. 605 - 614
Copyright
Copyright © The Nutrition Society 1994

References

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