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Biochemical aspects of malabsorption in marasmus: effect of dietary rehabilitation

Published online by Cambridge University Press:  24 July 2007

H. C. Mehta ,
A. S. Saini ,
Harjit Singh  and
P. S. Dhatt
H. C. Mehta
Affiliation:
Department of Biochemistry and Medical College and Hospital, Rohtak-124001, Haryana, India
A. S. Saini
Affiliation:
Department of Biochemistry and Medical College and Hospital, Rohtak-124001, Haryana, India
Harjit Singh
Affiliation:
Department of Biochemistry and Medical College and Hospital, Rohtak-124001, Haryana, India
P. S. Dhatt
Affiliation:
Department of Paediatrics, Medical College and Hospital, Rohtak-124001, Haryana, India
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Abstract

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1. Sixty marasmic children were investigated for the absorption of xylose, proteins and fats. Their duodenal juice samples were also analysed for bile salts and microflora.

2. The marasmic children were then studied in three groups of twenty by allocating them to three different dietary schedules: a high-protein diet (30% of the total energy from protein), a high-fat diet (40% of the total energy from fat) and a high-carbohydrate diet (70% of the total energy from carbohydrate) for 2 weeks and the previous measurements repeated.

3. Whereas the high-fat diet resulted in improved fat absorption, along with an increase in total and conjugated bile acids, and the high-carbohydrate diet led to improved xylose absorption, the diet rich in protein resulted in an improvement in the absorption of all three dietary ingredients. It appears that a high-protein diet improves the overall absorption process by improving the intestinal environment as a whole, while high-carbohydrate and high-fat diets bring about adaptive changes related to the respective absorptive processes.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 54 , Issue 3 , November 1985 , pp. 567 - 575
Copyright
Copyright © The Nutrition Society 1985

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