Hostname: page-component-586b7cd67f-2plfb Total loading time: 0 Render date: 2024-11-20T14:22:10.788Z Has data issue: false hasContentIssue false
  • English
  • Français

Bioavailability of selenium from raw or cured selenomethionine-enriched fillets of Atlantic salmon (Salmo salar) assessed in selenium-deficient rats

Published online by Cambridge University Press:  09 March 2007

Robin Ørnsrud  and
Mette Lorentzen
Robin Ørnsrud*
Affiliation:
Directorate of Fisheries, Institute of Nutrition, Strandgt. 229, P.O. box 185 Sentrum, N-5804 Bergen, Norway
Mette Lorentzen
Affiliation:
X-lab, Ibsensgt. 104 5052 Bergen, Norway
*
*Corresponding author: Dr R. Ørnsrud, fax +47 55 23 80 95, email [email protected]
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The bioavailability of Se from raw and cured selenomethionine-enriched (Se-enriched) salmon fillets was assessed in Se-deficient male albino rats (Mol: Wist). A low-Se Torula yeast feed was supplemented with 0, 50, 100, 150 or 200 μg Se/kg as sodium selenite or as Se from raw or cured Se-enriched salmon. The diets were fed to weanling rats for 10 and 30 d. Bioavailability of Se was assessed by metabolic balance, Se accumulation in femur, muscle, liver and plasma, and induction of Se-dependent glutathione peroxidase (EC 1·11·1.9; GSHpx) in plasma as response parameters. Except for the metabolic balance results, the slope-ratio method was used when calculating Se bioavailability from raw or cured Se-enriched fish fillets (test food) relative to sodium selenite (standard). The data for fractional apparent absorption and fractional retention showed differences (P<0·05) among all three Se sources in the order raw salmon > cured salmon > selenite. At 10 d, Se from raw and cured Se-enriched fish fillets tended to be more bioavailable than selenite. This was supported by the observations for Se accumulation in femur and muscle and induction of GSHpx activity. At 30 d, all response parameters showed a higher bioavailability of Se from raw and cured Se-enriched fish fillets compared with selenite. Differences (P<0·05) in Se accumulation in muscle at 10 and 30 d, and differences (P<0·05) in fractional apparent absorption and fractional retention suggested that curing salmon altered the utilisation of Se. The experimental results showed that enrichment of fish fillets with selenomethionine yields fillets with high Se bioavailability.

Keywords

Bioavailability of seleniumSelenomethionine-enriched salmonProcessed salmonSelenium
Type
Research Article
Information
British Journal of Nutrition , Volume 87 , Issue 1 , January 2002 , pp. 13 - 20
Copyright
Copyright © The Nutrition Society 2002

References

Alexander, AR, Whanger, PD & Miller, LT (1983) Bioavailability to rats of selenium in various tuna and wheat products. Journal of Nutrition 113, 196–204.CrossRefGoogle ScholarPubMed
Behne, D, Kyriakopoulos, S, Scheid, S & Gessner, H (1991) Effects of chemical form and dosage on the incorporation of selenium into tissue proteins of rats. Journal of Nutrition 121, 806–814.CrossRefGoogle Scholar
Behne, D, Weiss-Novak, C, Kalklösch, M, Westphal, C, Gessner, H & Kyriakopoulos, A (1995) Studies on the distribution and characteristics of new mammalian selenium-containing proteins. Analyst 120, 823–825.CrossRefGoogle Scholar
Bopp, BA, Sonders, RC & Westerton, JW (1982) Metabolic fate of selected selenium compounds in laboratory animals and man. Drug Metabolism Reviews 13, 271–318.CrossRefGoogle Scholar
Bradford, MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72, 248–254.CrossRefGoogle ScholarPubMed
Combs, GF & Combs, SB (1986) The Role of Selenium in Nutrition, Orlando, FL: Academic Press.Google Scholar
Crooke, WM & Simpson, WE (1971) Determination of ammonium in Kjeldahl digests of crops by an automated procedure. Journal of the Science of Food and Agriculture 22, 9–10.CrossRefGoogle Scholar
Douglass, JS, Morris, VC, Soares, JH Jr & Levander, OA (1981) Nutritional availability to rats of selenium in tuna, beef kidney and wheat. Journal of Nutrition 111, 2180–2187.CrossRefGoogle ScholarPubMed
Eskeland, B (1988) Mineraler. Forekomst og tap under ulike matvarefremstillingsprosesser (in Norwegian). InforMat 1, 99–101.Google Scholar
Fairweather-Tait, SJ (1992) Bioavailability of trace elements. Food Chemistry 43, 213–217.CrossRefGoogle Scholar
Finney, DJ (1978) Statistical Method in Biological Assay, 3rd ed., Oxford, London: Alden Press.Google Scholar
Flohé, L & Günzler, KA (1984) Assays of glutathione peroxidase. Methods in Enzymology 105, 114–121.CrossRefGoogle ScholarPubMed
Greger, JL & Marcus, RE (1981) Effect of dietary protein, phosphorous and sulphur amino acids on selenium metabolism of adult males. Annals of Nutrition and Metabolism 25, 97–108.CrossRefGoogle Scholar
Hassan, S, Hakkarainen, J & Lindberg, PO (1987) Bioavailability to chicks of selenium in wheat and fish meal. Journal of Veterinary Medicine 34A, 353–363.CrossRefGoogle Scholar
Hassan, S, Hakkarainen, J, Lindberg, P & Sankari, S (1993) Response of whole blood glutathione peroxidase and selenium in chicks fed with sodium selenite, wheat and fish meal. Animal Feed Science and Technology 41, 103–111.CrossRefGoogle Scholar
Higgs, DJ, Morris, VC & Levander, OA (1972) Effect of cooking on selenium content of foods. Journal of Agricultural and Food Chemistry 20, 678–680.CrossRefGoogle ScholarPubMed
House, WA & Welch, RM (1989) Bioavailability of and interactions between zinc and selenium in rats fed wheat grain intrinsically labeled with 65Zn and 75Se. Journal of Nutrition 119, 916–921.CrossRefGoogle ScholarPubMed
Knudsen, ER, Lorentzen, M & Julshamn, K (1992) Biological availability to rats of selenium from cod (Gadus morhua) and selenomethionine relative to sodium selenite. Fiskeridirektoratets Skrifter Serie Ernæring 5, 111–120.Google Scholar
Lie, Ø, Lied, E, Måge, A, Njaa, LR & Sandnes, K (1994) Nutrient content of fish and shellfish. Fiskeridirektoratets Skrifter Serie Ernæring 6, 83–105.Google Scholar
Lorentzen, M (1990) Fisk som selenkilde – en vurdering av forskjellige formers biologiske tilgjengelighet hos rotter med lav selenstatus (in Norwegian). Cand Scient Thesis, University of Bergen, Norway.Google Scholar
Lorentzen, M, Maage, A & Julshamn, K (1994) Effects of dietary selenite or selenomethionine on tissue selenium levels of Atlantic salmon (Salmon salar). Aquaculture 121, 359–367.CrossRefGoogle Scholar
Miller, D, Soares, JH, Bauersfeld, P & Cuppett, SL (1972) Comparative selenium retention by chicks fed sodium selenite, selenomethionine, fish meal and fish solubles. Poultry Science 51, 1669–1673.CrossRefGoogle ScholarPubMed
Mortensen, AB & Wallin, H (1989) Gravimetric determination of ash in foods: NMKL collaborative study. Journal of the Association of Official Analytical Chemists 72, 481–483.Google ScholarPubMed
Mutanen, ML & Mykkänen, HM (1984) Effect of dietary fat on plasma glutathione peroxidase levels and intestinal absorption of 75Se-labeled sodium selenite in chicks. Journal of Nutrition 114, 829–834.CrossRefGoogle ScholarPubMed
Nakahara, T (1995) Hydride generation techniques in atomic spectroscopy. Advanced Atomic Spectroscopy 2, 139–178.CrossRefGoogle Scholar
National Research Council (1995) Nutrient Requirements for Laboratory Animals, Washington, DC: National Academy Press.Google Scholar
Ochoa-Solano, A & Gitler, C (1968) Incorporation of 75Se-Selenomethionine and35S-Methionine into chicken egg white proteins. Journal of Nutrition 94, 243–248.CrossRefGoogle ScholarPubMed
Ringdal, O, Bjørnestad EØ, & Julshamn, K (1985) Comparative utilisation of fish selenium and inorganic selenite by rats of normal selenium status. Annals of Nutrition and Metabolism 29, 297–305.CrossRefGoogle ScholarPubMed
RIVO – The Netherlands Institute for Fisheries Research (2000) Speciation and bioavailability of selenium from processed and tailor-made fishery products, pp. 3–23EU FAIR Project CT95 0771, Wageningen, Wageningen UR.Google Scholar
Shen, LH, Hook-van Nieuwenhuizen, M & Luten, JB (1997) Speciation and in vitro bioavailability of selenium in fishery products. In Seafood from Producer to Consumer, Integrated Approach to Quality, pp. 653–663 [Luten, JB, Borreson, T and Oehlensclager, J, editors]. Amsterdam: Elsevier Science B.V.Google Scholar
Shi, B & Spallholz, JE (1994 a) Bioavailability of selenium from raw and cooked ground beef assessed in selenium-deficient Fischer rats. Journal of the American College of Nutrition 13, 95–101.CrossRefGoogle ScholarPubMed
Shi, B & Spallholz, JE (1994 b) Selenium from beef is highly bioavailable as assessed by liver glutathione peroxidase (EC 1.11.1.9.) activity and tissue selenium. British Journal of Nutrition 72, 873–881.CrossRefGoogle ScholarPubMed
Smith, AM & Picciano, MF (1987) Relative bioavailability of seleno-compounds in the lactating rat. Journal of Nutrition 117, 725–731.CrossRefGoogle ScholarPubMed
Sunde, RA, Gutzke, GE & Hoekstra, WG (1981) Effect of dietary methionine on the biopotency of selenite and selenomethionine in rat. Journal of Nutrition 111, 76–86.CrossRefGoogle Scholar
Swanson, CA, Patterson, BH, Levander, OA, Veillon, C, Taylor, PR, Helzlouer, K, McAdam, PA & Zech, LA (1991) Human [74Se]selenomethionine metabolism: a kinetic model. American Journal of Clinical Nutrition 257, R556–R567.Google Scholar
Wen, HY, Davis, RD, Shi, B, Chen, JJ, Chen, L, Boylan, M & Spallholz, JE (1997) Bioavailability of selenium from veal, chicken, beef, pork, lamb, flounder, tuna, selenomethionine, and sodium selenite assessed in selenium-deficient rats. Biological Trace Element Research 58, 43–53.CrossRefGoogle ScholarPubMed
Whanger, PD, Pedersen, ND, Hatfield, J & Westvig, PH (1976) Absorption of selenite and selenomethionine from ligated digestive tract segments in rats. Proceedings of the Society of Experimental Biological Medicine 153, 295–301.CrossRefGoogle ScholarPubMed
Windisch, W, Gabler, S & Kirchgessner, M (1998) Effect of selenite, seleno cysteine and seleno methionine on the selenium metabolism of 75Se labeled rats. Journal of Animal Physiology and Animal Nutrition 78, 67–74.CrossRefGoogle Scholar
Zar, J (1996) Biostatistical Analysis, 3rd ed., Upper Saddle River, NJ: Prentice-Hall International.Google Scholar