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Apparent zinc absorption by rats from foods labelled intrinsically and extrinsically with 67Zn

Published online by Cambridge University Press:  09 March 2007

Susan J. Fairweather-Tait ,
Thomas E. Fox ,
S. Gabrielle Wharf ,
John Eagles ,
Helen M. Crews  and
Robert Massey
Susan J. Fairweather-Tait
Affiliation:
AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA
Thomas E. Fox
Affiliation:
AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA
S. Gabrielle Wharf
Affiliation:
AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA
John Eagles
Affiliation:
AFRC Institute of Food Research, Colney Lane, Norwich NR4 7UA
Helen M. Crews
Affiliation:
MAFF Food Safety Directorate, Food Science Laboratory, Colney Lane, Norwich NR4 7UQ
Robert Massey
Affiliation:
MAFF Food Safety Directorate, Food Science Laboratory, Colney Lane, Norwich NR4 7UQ
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Abstract

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A variety of foods (peas (Pisum sativum), chicken meat, eggs, goat's milk, human milk) enriched with the stable isotope 67Zn were prepared by means of intrinsic- and extrinsic-labelling procedures. They were fed to rats and apparent absorption of 67Zn determined from faecal excretion measurements using thermal ionization mass spectrometry. There were significant differences in the absorption of the extrinsic and intrinsic label which differed in magnitude between the foods tested. The extrinsic 67Zn was less well absorbed in peas, chicken meat, eggs, and human milk than intrinsic 67Zn, but in goat's milk the extrinsic 67Zn was better absorbed than the intrinsic label. These results demonstrate that extrinsically-added stable Zn isotopes do not fully exchange with endogenous Zn in many foods, and illustrate the need for caution when using extrinsic labels for Zn bioavailability studies.

Keywords

Zn absorptionStable Zn isotopesIntrinsic and extrinsic labellingZn bioavailability
Type
Bioavailability and Utilization of Inorganic Nutrients
Information
British Journal of Nutrition , Volume 66 , Issue 1 , July 1991 , pp. 65 - 71
Copyright
Copyright © The Nutrition Society 1991

References

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